====== Patient-Level Prediction Workgroup ====== **Objective:** The overall objective of this workgroup (WG) is to establish a standardized process for developing accurate and well-calibrated patient-centered predictive models that can be utilized for multiple outcomes of interest and can be applied to observational healthcare data from any patient subpopulation of interest. Effective exploitation of the massive dataset available in the OMOP CDM demands novel methodology and an interdisciplinary approaches to deal with the by nature sparse and irregular-spaced longitudinal EHR data. Dimensionality reduction methods will be assessed and developed to deal with the massive amount of data. Furthermore, the WG will develop methods to leverage temporal information and will study how to incorporate expert knowledge, e.g. automatically extracted prior knowledge from LAERTES, to improve the performance of the prediction models. The WG aims to develop the open source Person-Level Assessment of Treatment Outcomes (PLATO) tool integrated in the OHDSI framework. This would allow all OHDSI members to produce individualized risk for all medical interventions and all health outcomes of interest, based on personal demographics, medical history, and health behaviors. **Starting 2020, the Patient-Level Predictions meetings will be combined with the Population-Level Effect Estimation meetings. The team still has its own research agenda.** Links: [[https://academic.oup.com/jamia/advance-article/doi/10.1093/jamia/ocy032/4989437|Jamia Paper 2018 Describing our Framework for PLP]]\\ **Project Lead:** [[http://www.ohdsi.org/who-we-are/collaborators/peter-rijnbeek/|Peter Rijnbeek, PhD]] **Project Co-Lead:** Jenna Reps, PhD **Members:** Alexandros Rekkas, MSc, Erasmus University Medical Center, The Netherlands\\ Adler Perotte, MD, Columbia University New York\\ Andrew Williams, PhD, Maine Medical Center Research Institute\\ Anthony Sena, Janssen Research & Development\\ Ban Tawfik, PhD, IQVIA\\ Daniel Prieto, MD PhD, NDORMS, University of Oxford\\ David Dorr, MD, MS, Oregon Health & Science University\\ David Kent, PhD, Tufts Medical Center\\ David Madigan, PhD, Columbia University New York\\ David Sontag, PhD, NYU, New York\\ Ewout Steyerberg, PhD, Erasmus Medical Center, Rotterdam, The Netherlands\\ Feifan Liu, PhD, University of Massachusetts Medical School\\ George Hripcsak, MD, MS, Columbia University, New York\\ Gwyn Jones, PhD, IMS Health\\ Hamed Abedtash, PharmD, Indiana University School of Informatics and Computing\\ Harietta Eleftherochorinou, PhD, IQVA\\ Henrik John, MSc, Erasmus Medical Center, Rotterdam, The Netherlands\\ Jack LI, PhD, Taipei Medical University\\ James Weaver, MPH, MS, Janssen Research & Development\\ Jenna Reps (co-lead), PhD, Janssen Research & Development\\ Johan van der Lei, MD, PhD, Erasmus Medical Center, Rotterdam, The Netherlands\\ Joydeep Ghosh, PhD, Unversity of Texas at Austin\\ Ken Jung, Stanford University\\ Kenney Ng, IBM Research\\ Klara Berensci, MSc, AARHUS University, Denmark\\ Li Xiaochun, PhD, Indiana University School of Medicine\\ Lisa Schilling, MD, MSPH, University of Colorado\\ Marc Suchard, MD, PhD, University of California\\ Martijn Schuemie, PhD, Janssen Research & Development\\ Mihaela van der Schaar, PhD, UCLA Electrical Engineering Department\\ Narges Razavian, PhD, NYU, New York\\ Nick Tatonetti, PhD, Columbia University, New York\\ Nicole Pratt, PhD, University of South Australia\\ Niklas Noren, PhD, Uppsala Monitoring Centre, Uppsala Sweden\\ Patrick Ryan, PhD, Janssen Research & Development\\ Peter Rijnbeek (lead), PhD, Erasmus Medical Center, Rotterdam, The Netherlands\\ Philippe Ravaud, PhD, Centre de Recherche Inserm Epidémiologie et Statistique Paris Sorbonne Cité\\ Rae Woong Park, PhD, MS Ajou university School of Medicine\\ Raphaël Porcher, PhD, Centre de Recherche Inserm Epidémiologie et Statistique Paris Sorbonne Cité\\ Rebecca L Barter, UC Berkeley\\ Richard Boyce, PhD, University of Pittsburgh School of Medicine\\ Robert Zusterzeel, PhD, Center for Drug Evaluation and Research of the FDA\\ Ross Williams, MSc, Erasmus Medical Center, Rotterdam, The Netherlands\\ Sarah Poole, Stanford University\\ Seng Chan You, MD, MS Ajou university School of Medicine \\ Suchi Saria, PhD, Johns Hopkins University\\ Shelby Martin, MS, RD, Oregon Health & Science University\\ Sheena Miller, BA, Oregon Health & Science University\\ Uri Shalit, PhD, New York University\\ Usman Iqball, PhD, Taipei Medical University\\ Tomas Bergvall, PhD, Uppsala monitoring Centre, Uppsala Sweden\\ Zixiao Shen, School of Computer Science, University Nottingham, UK\\ **Start Date:** January 2016 **WG Recordings:**\\ 2020 The recordings of the meetings can be found on the Population-Level Effect Estimation [[https://www.ohdsi.org/web/wiki/doku.php?id=projects:workgroups:est-methods|Wiki page]]. 2019 Western Hemisphere Meetings\\ 2019-07-11: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EaRVgRsEpCZHrByQvYX47R8BeXQqUu6E-4gvYU9exKF_0g?e=n0uaRG|Recording]][[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/EZ_xTMmz75xDtY0ynVZDyicBJixR4nw9wz4yRiksGSmM4Q?e=e8cdcF|Slides]]\\ 2019-06-19: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EbcvSJThtPNOr8dzUQzPBDoBlZ6HUOeablvkGmR2IXB5Ow?e=FbW8B2|Recording]][[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/EeX7wQe2xA9FrzYGPCnLt_wBT3_B_GkyxhQVRQE5PvMvKg?e=JZAMbo|Slides]]\\ 2019-05-15: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EYBN6Z73Q65Fm627QXueLloBVCU5RH5R_sM2rrUs2YYDiQ?e=BVKD9E|Recording]] \\ 2019-04-10: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EbzgmDhpJ3NHrgJh4IUaNeABWvEPjtOH0CkvIE2c9Mhm8w?e=70NRgz|Recording]] [[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/EXhE2d600bBCojdRzA0H3jIBZIrsdVghQ9289fKorozkmA?e=9JIQB2|Slides]]\\ 2019-03-13: [[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/EXhE2d600bBCojdRzA0H3jIBZIrsdVghQ9289fKorozkmA?e=9JIQB2|Recording]]\\ 2018 Western Hemisphere Meetings\\ 2018-02-21: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EeB24993JoZGpuGYB5BkUKYBC1G1cQf1DLp_slhe1Zj7-Q?e=CxD1Cz|Recording]] 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Eastern Hemisphere Meetings\\ 2018-02-28: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EaXXhOBpncRPsXuzNyCGQSYB-6H7ni8f5LGXRkdYpr3BDQ?e=iHGwYn|Recording]] [[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/Ed996F-nTitFig-aBJv_f7sB0b2JCnkGUZJI5gpMZcHgxw?e=DNdi9k|Slides]]\\ 2018-03-28: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/EQHbsDXCTBdNgpEuEaNqgdEBRrNxEp3c_N6Hy3T1KESG-Q?e=HaqrXD|Recording]] [[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/EeOOg3sbJFFCsvyyDe_wjkcB3yTClgiB_VJoBErSa7myqw?e=YvD2tM|Slides]]\\ 2018-04-25: [[https://mieur.sharepoint.com/:v:/g/IPCI/PREDICT/Eb6nNoAS-slMn1LWU4dsr2MB5REkaKJ69TyAOx9iZZzaMQ?e=tkYxzS|Recording]] [[https://mieur.sharepoint.com/:p:/g/IPCI/PREDICT/EYoI8OCSGP9FoJ25o0as1zIBoiCpJuTw78jLW163TGtIyQ?e=BfPoHy|Slides]]\\ 2017 Western Hemisphere Meetings\\ 2017-01-11: [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?docid=090454f71b61c424784ec7e86282b8923&authkey=Af_hbs-TM3flKn5mFn40NCs|Recording]] 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[[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=WBhk98t%2f7993KUB2H8QAWEhWCIZZvs1i5lDU%2b0al8oY%3d&docid=00ef73c4c20e54e69842f70843b665606&rev=1|Slides]]\\ 2016-09-07: [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=jmQtIthOv0jvZHBPjDKdThiy0JnVaqEnSEjdvxDKIhQ%3d&docid=06d0199bf5ce246f58f21216f4ba643bd&rev=1|Recording]] \\ 2016-10-19: [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=%2fpwt9Z5Lr5LoACJaEN5MMVG6Ernm8cCmOenqEqeYYB8%3d&docid=0abda8cda658443808946731f1f1a0bb1&rev=1|Recording]] [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=nwWU7d1ZZvYRe3mWe9Y5Vgkr8ZtRYdOwwydrRcncJfw%3d&docid=0105948756ff1402eb6b70afc1faabb2a&rev=1|Slides]]\\ 2016-11-02: [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=N4vO5Xtlt%2fpuRVo09bggNbCmEB74vqtXQRqwsLMghnU%3d&docid=0383ec29497fe486db239cb18dbff60f7&rev=1|Recording]] [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=IE8l7iQSYqXEESjKA9A4FP4%2fBDVjip5OQnXdqn7EfQI%3d&docid=0b944c8363caf488b9f7a08389195afce&rev=1|Slides]]\\ 2016-11-30: [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=wSSBU2PXowERnppCauLvJVdn9nWlXj6njehUmS9q8%2fw%3d&docid=0e0b66fe549c242b6ac0e11da0ee11851&rev=1|Recording]] [[https://mieur.sharepoint.com/IPCI/PREDICT/_layouts/15/guestaccess.aspx?guestaccesstoken=NfskPuQC6euthcVjrUpbUoE24esiWNHB3sBN3wDGKCs%3d&docid=08eb6d12fcc7f4eb0830fe8d7af92ebbf&rev=1|Slides]]\\ **Github:** **Repository:** [[https://github.com/OHDSI/PatientLevelPrediction]] ==== Meetings (Telecon Info) ==== ------------------------------------------------------- Meeting information There is a monthly Eastern and Western Hemisphere meeting of the PLP group on Wednesdays: Eastern Hemisphere (Monthly as of 2018-02-28): 3 pm Hong Kong / Taiwan \\ 4 pm South Korea \\ 5.30 pm Adelaide \\ 8 am UK time \\ 9 am Central European time \\           Western Hemisphere (Monthly as of 2018-2-21): 6 pm Central European time \\ 5 pm Uk time \\ 12 pm New York \\ 9 am Los Angeles / Stanford \\ The gotomeeting details are identical for both meetings: 1. Please join my meeting. https://global.gotomeeting.com/join/972917661 2. Use your microphone and speakers (VoIP) - a headset is recommended. Or, call in using your telephone. Netherlands: +31 (0) 208 084 055\\ Australia: +61 2 8355 1034\\ Austria: +43 7 2088 1036\\ Belgium: +32 (0) 28 93 7002\\ Canada: +1 (647) 497-9372\\ Denmark: +45 89 88 03 61\\ Finland: +358 (0) 942 45 0382\\ France: +33 (0) 170 950 586\\ Germany: +49 (0) 692 5736 7206\\ Ireland: +353 (0) 19 030 053\\ Italy: +39 0 693 38 75 53\\ New Zealand: +64 4 974 7243\\ Norway: +47 23 96 01 18\\ Spain: +34 932 20 0506\\ Sweden: +46 (0) 853 527 818\\ Switzerland: +41 (0) 225 3311 20\\ United Kingdom: +44 (0) 330 221 0098\\ United States: +1 (571) 317-3116\\ Access Code: 972-917-661 Audio PIN: Shown after joining the meeting Meeting ID: 972-917-661 **Github Issues:** [[https://github.com/OHDSI/PatientLevelPrediction/issues]]