documentation:next_cdm:denominator_units
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documentation:next_cdm:denominator_units [2017/03/07 03:26] cgreich |
documentation:next_cdm:denominator_units [2017/07/07 15:20] (current) clairblacketer |
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| ===== Denominator Units for liquid drugs and quantity field in DRUG_EXPOSURE ===== | ===== Denominator Units for liquid drugs and quantity field in DRUG_EXPOSURE ===== | ||
| + | === Proposals are now tracked as github issues === | ||
| + | [[https://github.com/OHDSI/CommonDataModel/issues/72|link to github issue]] | ||
| * Requester: Klaus Bonadt | * Requester: Klaus Bonadt | ||
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| ^ 2 ^ Puffs of an inhaler ^ | ^ 2 ^ Puffs of an inhaler ^ | ||
| ^ :::|Example: 150 puffs of 21174430 "Nicotine 0.5 MG/ACTUAT [Nicorette]". Note: There is no difference to use case 1 besides that the DRUG_STRENGTH table has {actuat} in the denominator_unit. In this case the strength is provided in the numerator.| | ^ :::|Example: 150 puffs of 21174430 "Nicotine 0.5 MG/ACTUAT [Nicorette]". Note: There is no difference to use case 1 besides that the DRUG_STRENGTH table has {actuat} in the denominator_unit. In this case the strength is provided in the numerator.| | ||
| - | ^ DRUG_STRENGTH | The denominator_unit is {actuat}. The numerator_value and numerator_unit contain the dose per actuation (puff) | | + | ^ DRUG_STRENGTH | The denominator_unit is {actuat}. The numerator value and numerator unit contain the dose per actuation (puff) | |
| ^ DRUG_EXPOSURE | Quantity refers to the number puffs, e.g. 150 | | ^ DRUG_EXPOSURE | Quantity refers to the number puffs, e.g. 150 | | ||
| ^ ''Total dose=''|''quantity x numerator_value [numerator_unit_concept_id]''| | ^ ''Total dose=''|''quantity x numerator_value [numerator_unit_concept_id]''| | ||
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| ^ 3 ^ Quantified Drugs^ | ^ 3 ^ Quantified Drugs^ | ||
| ^ :::|Example: 43275770 "60 ML Acetaminophen 50 MG/ML Oral Solution", meaning, there are 60 mL of Acetaminophe (Paracetamol) of a concentration of 50 mg/mL. Two such bottles are prescribed. | | ^ :::|Example: 43275770 "60 ML Acetaminophen 50 MG/ML Oral Solution", meaning, there are 60 mL of Acetaminophe (Paracetamol) of a concentration of 50 mg/mL. Two such bottles are prescribed. | | ||
| - | ^ DRUG_STRENGTH | The concentration is given in the numerator/denominator fields, with the denominator_unit either mg or mL, and the denominator_value typically not 1. E.g. 3000 mg in 60 mL. | | + | ^ DRUG_STRENGTH | The concentration is given in the numerator/denominator fields, with the denominator unit either mg or mL, and the denominator value typically not 1. E.g. 3000 mg in 60 mL. | |
| ^ DRUG_EXPOSURE | Quantity refers to a fraction or multiple of the container. E.g. 2| | ^ DRUG_EXPOSURE | Quantity refers to a fraction or multiple of the container. E.g. 2| | ||
| ^ ''Total dose=''|''quantity x numerator_value [numerator_unit_concept_id]''| | ^ ''Total dose=''|''quantity x numerator_value [numerator_unit_concept_id]''| | ||
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| ^ 4 ^Liquid drugs, or drugs where the amount can be split randomly. The total amount in given in quantity^ | ^ 4 ^Liquid drugs, or drugs where the amount can be split randomly. The total amount in given in quantity^ | ||
| ^ :::|Example: 42799258 "Benzyl Alcohol 0.1 ML/ML / Pramoxine hydrochloride 0.01 MG/MG Topical Gel" dispensed in a 1.25 oz pack.| | ^ :::|Example: 42799258 "Benzyl Alcohol 0.1 ML/ML / Pramoxine hydrochloride 0.01 MG/MG Topical Gel" dispensed in a 1.25 oz pack.| | ||
| - | ^ DRUG_STRENGTH | The concentration is given in the numerator/denominator fields, with the denominator_unit either mg or mL, and the denominator_value null. E.g. Benzyl Alcohol in mL and Pramoxine hydrochloride in mg// | | + | ^ DRUG_STRENGTH | The concentration is given in the numerator/denominator fields, with the denominator unit either mg or mL, and the denominator value as null. E.g. Benzyl Alcohol in mL and Pramoxine hydrochloride in mg | |
| ^ DRUG_EXPOSURE | Quantity refers to the unit provided in DRUG_STRENGTH. Since both mL and mg are found mg is preferred. E.g. 1.25 x 30 (conversion factor oz -> mL) x 1000 (conversion mL -> mg) = 37,000 | | ^ DRUG_EXPOSURE | Quantity refers to the unit provided in DRUG_STRENGTH. Since both mL and mg are found mg is preferred. E.g. 1.25 x 30 (conversion factor oz -> mL) x 1000 (conversion mL -> mg) = 37,000 | | ||
| - | ^ ''Ingredient dose=''|''quantity x numerator_value [numerator_unit_concept_id]''| | + | ^ ''Total dose=''|''quantity x numerator_value [numerator_unit_concept_id]''| |
| ^ :::|''Benzyl Alcohol dose = 37,000 x 0.1 mL x 0.001 = 3.7 mL''| | ^ :::|''Benzyl Alcohol dose = 37,000 x 0.1 mL x 0.001 = 3.7 mL''| | ||
| ^ :::|''Pramoxine hydrochloride dose = 37,000 x 0.01 mg = 370 mg''| | ^ :::|''Pramoxine hydrochloride dose = 37,000 x 0.01 mg = 370 mg''| | ||
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| ^ 5 ^Compounded drugs^ | ^ 5 ^Compounded drugs^ | ||
| ^ :::|Example: 30 mL Ibuprofen 20% / Piroxicam 1% Cream.| | ^ :::|Example: 30 mL Ibuprofen 20% / Piroxicam 1% Cream.| | ||
| - | ^ DRUG_STRENGTH | Two separate entries for the ingredients of Ibuprofen and Piroxicam are required, with an amount_value of null and a unit of mg. | | + | ^ DRUG_STRENGTH | Two separate entries for the ingredients of Ibuprofen and Piroxicam are required, with an amount value of null and a amount unit of mg. | |
| - | ^ DRUG_EXPOSURE | Quantity refers to the total weight amount of the compounded ingredient. Use one record in the DRUG_EXPOSURE table for each compound. Eg.g 20% Ibuprofen in 30 mL = 6 mL, 1% Piroxicam in 30 mL = 0.3 mL// | | + | ^ DRUG_EXPOSURE | Quantity refers to the total weight amount of the compounded ingredient. Use one record in the DRUG_EXPOSURE table for each compound. Eg.g 20% Ibuprofen in 30 mL = 6 mL, 1% Piroxicam in 30 mL = 0.3 mL | |
| - | ^ ''Ingredient dose=''|Depends on the drugs involved: One of the use cases above.| | + | ^ ''Total dose=''|Depends on the drugs involved: One of the use cases above.| |
| ^ :::|''Ibuprofen dose = 6 x 1000 = 6000 mg''| | ^ :::|''Ibuprofen dose = 6 x 1000 = 6000 mg''| | ||
| ^ :::|''Piroxicam dose = 0.3 x 1000 = 300 mg''| | ^ :::|''Piroxicam dose = 0.3 x 1000 = 300 mg''| | ||
| ^ :::|//Note: At analysis time, the denominator should be checked for both ingredients in the DRUG_STRENGTH table. If it is not mg a conversion factor of 1000 should be applied to convert between mL/g and mg.//| | ^ :::|//Note: At analysis time, the denominator should be checked for both ingredients in the DRUG_STRENGTH table. If it is not mg a conversion factor of 1000 should be applied to convert between mL/g and mg.//| | ||
| | | | | | | | | ||
| - | ^ 6 ^Dose release over time, e.g. Patches^ | + | ^ 6 ^Drugs with delayed release over time, e.g. Patches^ |
| - | ^ :::|//Example: Ethinyl Estradiol 0.000833 MG/HR / norelgestromin 0.00625 MG/HR Weekly Transdermal Patch//| | + | ^ :::|Example: 1518199 "Ethinyl Estradiol 0.000833 MG/HR / norelgestromin 0.00625 MG/HR Weekly Transdermal Patch| |
| - | ^ DRUG_STRENGTH | The denominator units refer to hour.| | + | ^ DRUG_STRENGTH | The release is provided as numerator/denominator pair, with the denominator value as null and the denominator unit hour. E.g. Ethinyl Estradiol 0.000833 mg/h / norelgestromin 0.00625 mg/h| |
| - | ^ :::|//Example: Ethinyl Estradiol 0.000833 mg/h / norelgestromin 0.00625 mg/h//| | + | ^ DRUG_EXPOSURE | Quantity refers to the number of pieces. E.g. 1 patch. | |
| - | ^ DRUG_EXPOSURE | Quantity refers to the number of pieces.| | + | ^ ''Release rate=''|''numerator_value [numerator_unit_concept_id]''| |
| - | ^ :::|// Example: 1 patch// | | + | ^ :::|''Ethinyl Estradiol rate = 0.000833 mg/h''| |
| - | ^ ''Ingredient rate=''|''numerator_value [numerator_unit_concept_id]''| | + | ^ :::|''norelgestromin rate 0.00625 mg/h''| |
| - | ^ :::|''// Ethinyl Estradiol rate = 0.000833 mg/h//''| | + | |
| - | ^ :::|//''norelgestromin rate 0.00625 mg/h''//| | + | |
| ^ :::|//Note: This can be converted to a daily dosage by multiplying it with 24. (Assuming 1 patch at a time for at least 24 hours)//| | ^ :::|//Note: This can be converted to a daily dosage by multiplying it with 24. (Assuming 1 patch at a time for at least 24 hours)//| | ||
documentation/next_cdm/denominator_units.1488857194.txt.gz · Last modified: 2017/03/07 03:26 by cgreich
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