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documentation:vocabulary:drug [2016/06/13 05:38]
cgreich
documentation:vocabulary:drug [2021/10/23 08:00] (current)
adavydov
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 The drug exposure domain concepts capture records about the utilization of a Drug when ingested or otherwise introduced into the body. A Drug is a biochemical substance formulated in such a way that when administered to a Person it will exert a certain physiological or biochemical effect. The following products are **not** considered Drugs, but Devices: The drug exposure domain concepts capture records about the utilization of a Drug when ingested or otherwise introduced into the body. A Drug is a biochemical substance formulated in such a way that when administered to a Person it will exert a certain physiological or biochemical effect. The following products are **not** considered Drugs, but Devices:
  
-  * Radiopharmaceuticals +  * Diagnostic radiopharmaceuticals. 
-  * Contrast material for imaging +  * Contrast material for imaging ​(barium sulfate, gadolinium, etc.). 
-  * Nutritional products and supplements,​ including ​baby formula. In reality that results in the slightly arbitrary and in some cases difficult to ascertain situation that solutions of salts for parental use are Drugs (hydrating patients and maintaining ionic balance), while the addition of nutrients such as glucose or vitamins makes them devices (feeding patients). +  * Nutritional products and supplements,​ including ​infant feeding. In reality that results in the slightly arbitrary and in some cases difficult to ascertain situation that solutions of salts are Drugs (hydrating patients and maintaining ionic balance), while the addition of nutrients such as glucose or vitamins makes them devices (feeding patients)
-  * Products directly derived from blood (e.g. erythocytes or plasma)+  * Parenteral nutrition (aminoacids and/or lipid mixes). 
 +  * Solution for dialysis, catheter maintenance etc
 +  * Products directly derived from blood (erythrocytes,​ plasma, serum, thrombocytes),​ while immune globin or albumin preparations,​ monoclonal antibodies, coagulation factors and homeopathy derived from blood are Drugs. 
 +  * Transplants of any kind. 
 +  * Artificial saliva, artificial tears, and lubricants. 
 +  * Non-medicated cosmetics (creams, ointments, soaps, deodorants, shampoos), including SPF sunscreens. 
 +  * Glucometric strips, needles, tubes with anticoagulants,​ etc. 
 +  * Surgical materials like bone cement. 
 +  * Hemostatics materials (cellulose, flour, collagen, etc.). 
 +  * Disinfectants for inert surfaces. 
 + 
 +**Devices that contain drug substances ​(e.g. bone cement with antibioticsare considered Devices, but should obtain additional mapping to the Drug Domain concepts.**
  
 Drug domain Concepts should be used in the drug_concept_id of the DRUG_EXPOSURE the DRUG_ERA and the DOSE_ERA (both only at the Ingredient level) tables, or in the value_as_concept_id field of the OBSERVATION or MEASUREMENT table (e.g. for Measurements like "​Plasma level"​). Drug domain Concepts should be used in the drug_concept_id of the DRUG_EXPOSURE the DRUG_ERA and the DOSE_ERA (both only at the Ingredient level) tables, or in the value_as_concept_id field of the OBSERVATION or MEASUREMENT table (e.g. for Measurements like "​Plasma level"​).
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 ^Vocab^Name^Ingre dient^Drug strength^Dose form^Brand name^Quantity factor^Box size^Pack content ^Supplier^ ^Vocab^Name^Ingre dient^Drug strength^Dose form^Brand name^Quantity factor^Box size^Pack content ^Supplier^
 ^RxNorm|Ingredient| ​  ​x ​  | | | | | | | | ^RxNorm|Ingredient| ​  ​x ​  | | | | | | | |
-^:::|Brand Name| | | |  x  | | | | | 
 ^:::​|Clinical Drug Component| ​ x  |  x  | | | | | | | ^:::​|Clinical Drug Component| ​ x  |  x  | | | | | | |
 ^:::​|Clinical Drug Form|  x  | |  x  | | | | | | ^:::​|Clinical Drug Form|  x  | |  x  | | | | | |
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   * One-to-one mappings to all other Concept Classes   * One-to-one mappings to all other Concept Classes
  
-The internal relationships between Drug Concepts are derived from RxNorm relatinships and extended to cover the additional Concept Classes of the RxNorm Extension vocabulary:+The internal relationships between Drug Concepts are derived from RxNorm relatinships and extended to cover the additional Concept Classes of the RxNorm Extension vocabulary ​("​Drug"​ without any attribute means either "​Clinical"​ or "​Branded"​):
  
 ^Source^Original name^relatinship_id^Connecting Concept Classes^ ^Source^Original name^relatinship_id^Connecting Concept Classes^
-|RxNorm|consists_of|Consists of|Drug ​and Quantified Drug and Drug Component|+|RxNorm|consists_of|Consists of|Drug ​or Quantified Drug and Drug Component|
 |:::​|constitutes|Constitutes|Drug Component and Drug or Quantified Drug| |:::​|constitutes|Constitutes|Drug Component and Drug or Quantified Drug|
 |:::​|contained_in|Contained in|Drug or Quantified Drug and Pack| |:::​|contained_in|Contained in|Drug or Quantified Drug and Pack|
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 |:::​|tradename_of|Tradename of|Branded and Clinical Concept Class equivalents| |:::​|tradename_of|Tradename of|Branded and Clinical Concept Class equivalents|
 |:::​|tradename_of|Brand name of|Brand Name and Ingredient| |:::​|tradename_of|Brand name of|Brand Name and Ingredient|
-|:::| -  |Concept replaced by|Records ​in RXNATOMARCHIVE with merged_to_rxcui information| +|:::|  -  |Concept replaced by|Concepts ​in RXNATOMARCHIVE with merged_to_rxcui information| 
-|:::| -  |Concept replaces|Records ​in RXNATOMARCHIVE with merged_to_rxcui information|+|:::|  -  |Concept replaces|Concepts ​in RXNATOMARCHIVE with merged_to_rxcui information|
 |RxNorm Extension| ​ -  |Available as box|Drug and Drug Box| |RxNorm Extension| ​ -  |Available as box|Drug and Drug Box|
 |:::|  -  |Box of|Drug Box and Drug| |:::|  -  |Box of|Drug Box and Drug|
 |:::|  -  |Has marketed form|Drug and Marketed Product| |:::|  -  |Has marketed form|Drug and Marketed Product|
 |:::|  -  |Marketed form of|Marketed Product and Drug| |:::|  -  |Marketed form of|Marketed Product and Drug|
 +|:::|  -  |Has supplier|Drug and Supplier|
 +|:::|  -  |Supplier of|Supplier and Drug|
  
 For a discussion of the relationships between Drugs and Classifications and within Classifications please see the individual vocabulary sections. For a discussion of the relationships between Drugs and Classifications and within Classifications please see the individual vocabulary sections.
  
 ==== Drug Strength ==== ==== Drug Strength ====
-The Drug Domain has an additional DRUG_STRENGTH table defining the strength of each ingredient. This is defined for all Drug Concept Classes except Ingredient, Clinical Drug Form and Branded Drug Form, Dose Form and Brand Name. +The Drug Domain has an additional DRUG_STRENGTH table defining the strength of each ingredient. This is defined for all Drug Concept Classes except Ingredient, Clinical Drug Form and Branded Drug Form, Dose FormBrand Name and Supplier
documentation/vocabulary/drug.1465796304.txt.gz · Last modified: 2016/06/13 05:38 by cgreich