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implementation_international_drug_vocabulary [2019/07/22 16:24]
ekorchmar
implementation_international_drug_vocabulary [2019/07/22 16:27]
ekorchmar
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 ==== Combined target structure ==== ==== Combined target structure ====
-To incorporate a new set of drug information,​ a structure should be achieved that contains every Concept only once and preserves the RxNorm structure, no matter which vocabulary the additional Concept is coming from. In a way, it should create a mixed RxNorm/drug vocabularies union. +Standard concepts in [[documentation:​vocabulary:​drug|Drug domain]] are placed in a single comprehensive hierarchy based on their attributes. To correctly implement a vocabulary in CDM and find or build an counterpart for each source drug concept, following attributes must be extracted:
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-Standard concepts in [[documentation:​vocabulary:​drug|Drug domain]] are placed in a single comprehensive hierarchy based on their attributes. To correctly implement a vocabulary in CDM, following attributes must be extracted:+
  
   - **Ingredients**:​ active substance(-s) in pharmacological preparation. Examples: Aspirin, Trastuzumab,​ Ibuprofen etc.;   - **Ingredients**:​ active substance(-s) in pharmacological preparation. Examples: Aspirin, Trastuzumab,​ Ibuprofen etc.;
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 Brand Names that are simple combinations of generic international name of active substance and manufacturer name (e.g. "​Aspirin Bayer"​) should not appear as attributes for Drug Products. Manufacturer information should be stored as a concept with Supplier class. Brand Names that are simple combinations of generic international name of active substance and manufacturer name (e.g. "​Aspirin Bayer"​) should not appear as attributes for Drug Products. Manufacturer information should be stored as a concept with Supplier class.
  
-Concepts that belong to the source vocabulary, but do not belong to Drug domain by OMOP rules., should be classified as '​Device'​. Typically, these belong to different substance groups:+Concepts that belong to the source vocabulary, but do not belong to Drug domain by OMOP CDM conventions, should be classified as '​Device'​. Typically, these belong to different substance groups:
   * Radiographic contrasts and dyes (barium sulfate, radiolabeled iodides)   * Radiographic contrasts and dyes (barium sulfate, radiolabeled iodides)
   * Nutritional supplements without stated mechanism of pharmaceutical action (e.g. herbal complexes, homeopathic preparations)   * Nutritional supplements without stated mechanism of pharmaceutical action (e.g. herbal complexes, homeopathic preparations)
implementation_international_drug_vocabulary.txt · Last modified: 2021/06/09 10:15 by adavydov