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Objective: Questions of causality are fundamental inspirations behind innovations in philosophy, business, and science, including biomedicine. Answering causal questions leads to better predictive and prescriptive modeling. It is also the key to the correct identification of unknown effects as well as the latent factors that influence outcomes, and to produce hypotheses, validation, and proof.
Large-scale observational data offers a new window for verifying our existing causal understandings and for inferring new causal relationships at a fast pace. We are working to rethink the existing frameworks of causal inference in health sciences by introducing ideas from other scientific disciplines and by inventing new concepts and analytical methods.