Objective: The objective of this study is to characterize the prevalence of different treatment pathways within the first year of drug initiation for three chronic diseases: Hypertension, Type II Diabetes, and Depression.
Rationale: While numerous treatment guidelines exist for chronic conditions, there is a paucity of data on the real-world treatment pathways. A recent OHDSI study explored treatment pathways for chronic conditions based on 3 years of drug exposure. Additional interest exists for looking at treatment in the early phases of a disease, where switching may often occur. Additionally, focusing the analysis on a narrower timeframe post-initiation will increase the number of eligible patients and potentially provide additional insight into these pathways.
Project Leads: Jon Duke, Patrick Ryan, Richard Boyce, [others please add if interested]
Coordinating Institution(s): Regenstrief Institute, University of Pittsburgh, Janssen
Full Protocol: Pending
Initial Proposal Date: Pending
Launch Date: Pending
Study Closure Date: Pending
Results Submission: Email or SFTP
CDM: V4 or V5
Database Dialect: SQL Server, Postgres, Oracle
Software: SQL as above, R (optional)