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Early Treatment Pathways in Chronic Disease

Objective: The objective of this study is to characterize the prevalence of different treatment pathways within the first year of drug initiation for three chronic diseases: Hypertension, Type II Diabetes, and Depression.

Rationale: While numerous treatment guidelines exist for chronic conditions, there is a paucity of data on the real-world treatment pathways. A recent OHDSI study explored treatment pathways for chronic conditions based on 3 years of drug exposure. Additional interest exists for looking at treatment in the early phases of a disease, where switching may often occur. Additionally, focusing the analysis on a narrower timeframe post-initiation will increase the number of eligible patients and potentially provide additional insight into these pathways.

Project Leads: Jon Duke, Patrick Ryan, Richard Boyce, [others please add if interested]

Coordinating Institution(s): Regenstrief Institute, University of Pittsburgh, Janssen

Additional Participants:

Full Protocol: Pending

Initial Proposal Date: Pending

Launch Date: Pending

Study Closure Date: Pending

Results Submission: Email or SFTP


CDM: V4 or V5

Database Dialect: SQL Server, Postgres, Oracle

Software: SQL as above, R (optional)



Datasets Run

research/early_treatment_pathways_for_chronic_conditions.txt · Last modified: 2014/12/10 19:46 by jduke