Observational Health Data Sciences and Informatics

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====== Early Treatment Pathways in Chronic Disease ======

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**Objective:** The objective of this study is to characterize the prevalence of different treatment pathways within the first year of drug initiation for three chronic diseases: Hypertension, Type II Diabetes, and Depression. 

**Rationale:** While numerous treatment guidelines exist for chronic conditions, there is a paucity of data on the real-world treatment pathways.  A recent OHDSI study explored treatment pathways for chronic conditions based on 3 years of drug exposure.  Additional interest exists for looking at treatment in the early phases of a disease, where switching may often occur.  Additionally, focusing the analysis on a narrower timeframe post-initiation will increase the number of eligible patients and potentially provide additional insight into these pathways.

**Project Leads:** Jon Duke, Patrick Ryan, Richard Boyce,  [others please add if interested]

**Coordinating Institution(s):** Regenstrief Institute, University of Pittsburgh, Janssen

** Additional Participants:**

**Full Protocol:** Pending

**Initial Proposal Date:**  Pending

**Launch Date:**  Pending

**Study Closure Date:**  Pending

**Results Submission:** [[mailto:jonduke@regenstrief.org|Email]] or SFTP

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===== Requirements =====
**CDM:** V4 or V5

**Database Dialect:** SQL Server, Postgres, Oracle

**Software:**  SQL as above, R (optional) 
 
===== Code ===== 
[[https://github.com/OHDSI/StudyProtocols]]

===== Discussion ===== 
[[http://forums.ohdsi.org/t/ohdsi-study-1-treatment-pathways-in-chronic-disease/112|Treatment Pathways Discussion Thread]] 

===== Datasets Run ===== 



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