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research:pgx_drug_exposure

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research:pgx_drug_exposure [2015/02/17 17:52] – rkboyceresearch:pgx_drug_exposure [2017/01/15 00:04] (current) – rkboyce
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 <WRAP box justify round> <WRAP box justify round>
  
-**Objective:** Derive data that large healthcare organizations can combine data on risks of adverse events  and cost data to conduct cost-effectiveness / cost-benefit analyses for pre-emptive pharmacogenomics testing+**Objective:** Derive data that large healthcare organizations can combine with data on risks of adverse events  and cost data to conduct cost-effectiveness / cost-benefit analyses for pre-emptive pharmacogenomics testing
  
 **Rationale:** Very few studies have been conducted that report on the potential return on investment for pre-emptive pharmacogenomics testing. The studies that have been published  suggest that pre-emptive pharmacogenomics testing may produce a return on investment but much depends on if a sufficient number of drugs with pharmacogenes are covered by a single test. Since the current data are limited to relatively localized settings and might not be of generalizable use to other health organizations, it's of interest to implement a new study using the OHDSI research network.  **Rationale:** Very few studies have been conducted that report on the potential return on investment for pre-emptive pharmacogenomics testing. The studies that have been published  suggest that pre-emptive pharmacogenomics testing may produce a return on investment but much depends on if a sufficient number of drugs with pharmacogenes are covered by a single test. Since the current data are limited to relatively localized settings and might not be of generalizable use to other health organizations, it's of interest to implement a new study using the OHDSI research network. 
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 **Coordinating Institution(s):** University of Pittsburgh, Medical University of Vienna, Columbia University, Regenstrief Institute, Janssen R&D, AstraZeneca **Coordinating Institution(s):** University of Pittsburgh, Medical University of Vienna, Columbia University, Regenstrief Institute, Janssen R&D, AstraZeneca
  
-** Additional Participants:**  Patrick Ryan, Jon Duke, George Hripcsak, Abraham G. Hartzema, Christian Reich (seeking other collaborators)+** Additional Participants (currently seeking other collaborators):**  Patrick Ryan, Jon Duke, George Hripcsak, Abraham G. Hartzema, Christian Reich, Dan Malone 
  
-**Full Protocol:** //<if available, a link to protocol.  not necessary for initial planning>//+**Full Protocol:** [[https://docs.google.com/document/d/1u3AE5DtkEp3m8OcbwkGHtXBVefYGGJ_1RMO3OnqpXiY/edit|Google doc for the protocol]]
  
 **Initial Proposal Date:**  2/16/2015 **Initial Proposal Date:**  2/16/2015
  
-**Launch Date:**  //<fill out once finalized>//+**Launch Date:**  This was a test research network study and has met its objectives as of 12/1/2016.
  
 **Study Closure Date:  //<fill out once finalized>//** **Study Closure Date:  //<fill out once finalized>//**
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 ===== Code =====  ===== Code ===== 
-[[https://github.com/OHDSI/StudyProtocols/tree/master/Proposed%20Study%203%20-%20Incidence%20of%20exposure%20to%20PGx%20drugs|GitHub code for Proposed Study 3 - Incidence of exposure to PGx drugs]]+[[https://github.com/OHDSI/StudyProtocols/tree/master/PGxDrugStudy|GitHub code for Proposed Study 3 - Incidence of exposure to PGx drugs]]
  
 ===== Discussion =====  ===== Discussion ===== 
-//Post a thread letting everyone know about this new proposed study at [[http://forums.ohdsi.org/c/researchers]]// +[[http://forums.ohdsi.org/t/ohdsi-study-3-incidence-of-exposure-to-drugs-for-which-pre-emptive-pharmacogenomic-testing-is-available/387]] 
 + 
  
 ===== Datasets Run =====  ===== Datasets Run ===== 
research/pgx_drug_exposure.1424195554.txt.gz · Last modified: by rkboyce
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