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research:project_proposal_template

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research:project_proposal_template [2014/12/02 18:13] – [Discussion] jdukeresearch:project_proposal_template [2015/02/16 20:45] (current) – rkboyce
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-====== Treatment Pathways in Hypertension ======+====== Incidence of exposure to drugs for which pre-emptive pharmacogenomic testing is available  ======
  
 <WRAP box justify round> <WRAP box justify round>
  
-**Objective:** //<summarize study objective>//+**Objective:** Derive data that large healthcare organizations can combine data on risks of adverse events  and cost data to conduct cost-effectiveness / cost-benefit analyses for pre-emptive pharmacogenomics testing
  
-**Rationale:** //<summarize study rationale>//+**Rationale:** Very few studies have been conducted that report on the potential return on investment for pre-emptive pharmacogenomics testing. The studies that have been published  suggest that pre-emptive pharmacogenomics testing may produce a return on investment but much depends on if a sufficient number of drugs with pharmacogenes are covered by a single test. Since the current data are limited to relatively localized settings and might not be of generalizable use to other health organizations, it's of interest to implement a new study using the OHDSI research network. 
  
-**Project Lead(s):** //<initial proposers, list may grow>//+**Project Lead(s):** Richard D. Boyce, Matthias Samwald, Patrick Ryan, (seeking other collaborators)
  
-**Coordinating Institution(s):** //<your institution>//+**Coordinating Institution(s):** University of Pittsburgh, Medical University of Vienna
  
 ** Additional Participants:**  //<usually blank initially, list will grow as individuals are added who are not project leads>// ** Additional Participants:**  //<usually blank initially, list will grow as individuals are added who are not project leads>//
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 **Full Protocol:** //<if available, a link to protocol.  not necessary for initial planning>// **Full Protocol:** //<if available, a link to protocol.  not necessary for initial planning>//
  
-**Initial Proposal Date:**  +**Initial Proposal Date:**  2/16/2015
  
 **Launch Date:**  //<fill out once finalized>// **Launch Date:**  //<fill out once finalized>//
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 ===== Requirements ===== ===== Requirements =====
-**CDM:** //<V4 or V5 or both>//+**CDM:** V4 or V5
  
-**Table Accessed:**  //<e.g., person, drug_exposure, observations>//+**Table Accessed:**  DRUG_EXPOSURE, CONCEPT_ANCESTOR, CONCEPT_RELATIONSHIP, PERSON
  
 **Database Dialects:** SQL Server, Postgres, Oracle **Database Dialects:** SQL Server, Postgres, Oracle
  
-**Software:**  //<<e.g., R>// +**Software:** SQL and R 
    
 ===== Code =====  ===== Code ===== 
-[[https://github.com/OHDSI/StudyProtocols]]+[[https://github.com/OHDSI/StudyProtocols/tree/master/Proposed%20Study%203%20-%20Incidence%20of%20exposure%20to%20PGx%20drugs|GitHub code for Proposed Study 3 - Incidence of exposure to PGx drugs]]
  
 ===== Discussion =====  ===== Discussion ===== 
-//<Post a thread letting everyone know about this new proposed study at [[http://forums.ohdsi.org/c/researchers]]>// +//Post a thread letting everyone know about this new proposed study at [[http://forums.ohdsi.org/c/researchers]]// 
  
 ===== Datasets Run =====  ===== Datasets Run ===== 
-  * Truven +  * Truven CCAE in the IMEDS lab 
-  * Optum +  * Truven MDCD in the IMEDS lab 
-  * CPRD +  * Truven MDCR in the IMEDS lab
-  * Indiana Network for Patient Care+
  
  
 ~~NOTOC~~ ~~NOTOC~~
research/project_proposal_template.1417544008.txt.gz · Last modified: by jduke
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