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projects:workgroups:causal_inference [2019/11/24 02:29]
abbas
projects:workgroups:causal_inference [2024/07/28 12:34] (current)
abbas
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-**Coordinator:**+** Project Leads:**
  
 * [[https://​www.linkedin.com/​in/​ashojaee/​|Abbas Shojaee]] * [[https://​www.linkedin.com/​in/​ashojaee/​|Abbas Shojaee]]
 + * [[https://​www.linkedin.com/​in/​yalda-aryan/?​original_referer=https%3A%2F%2Fwww%2Egoogle%2Ecom%2F&​originalSubdomain=ir|Yalda Aryan]]
   ​   ​
  
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 ==== Causal Inference Using Composition of Transactions (CICT) ​ ==== ==== Causal Inference Using Composition of Transactions (CICT) ​ ====
  
-**Project Lead:** [[https://​www.linkedin.com/​in/​ashojaee/​|Abbas Shojaee]] 
  
-CICT is a novel computational method that uses large-scale health data to predict potential causal relationships ​ between clinical conditions, genes, proteins and other interacting factors. A pipeline for epidemiological etiological inference is also developed to validate the results of CICT. CICT and the validation pipeline have been used by different teams to identify latent risk factor ​and unknown effects of clinical conditions or procedures, which resulted in reporting of multiple novel findings during 2018-2019. Two large-scale population-level claims datasets from HCUP California and Florida have been used for discovery and validation. OHDSI will be used to empower the engine for the new phase. ​+CICT is a novel computational method that uses large-scale health data to predict potential causal relationships between clinical conditions. A pipeline for epidemiological etiological inference is also developed to validate the results of CICT. CICT and the validation pipeline have been used by different teams to identify latent risk factors ​and unknown effects of clinical conditions or procedures, which resulted in reporting of multiple novel findings during 2018-2019. Two large-scale population-level claims datasets from HCUP California and Florida have been used for discovery and validation. OHDSI will be used to empower the engine for the new phase. ​ 
 + 
 +**CICT pipeline can produce highly accurate novel hypotheses and analyses results at a fast pace. ** Accordingly,​ we are now open to collaboration requests from clinical researchers who are seeking novel hypotheses from data and/or epidemiological evidence from population-level data. We are also eager to start ** collaborations ** with individuals or organizations that can provide us access to large-scale claims/EMR datasets in OHDSI, based on their existing access.  
 + 
 +*** Publications and conference papers: *** 
 + 
 +[[https://​www.medrxiv.org/​content/​10.1101/​2021.03.08.21252412v1|Viral Pneumonia is Associated with Increased Risk and Earlier Development of Post-Inflammatory Pulmonary Fibrosis]] 
 + 
 +[[https://​academic.oup.com/​bib/​article/​24/​6/​bbad370/​7330999|Robust discovery of gene regulatory networks from single-cell gene expression data by Causal Inference Using Composition of Transactions]] 
 + 
 +[[https://​www.biorxiv.org/​content/​10.1101/​439117v1|Asthma-Neoplasms Relationships:​ New Insights Using Machine Inference, Epidemiological Reasoning, And Big Data]] 
 + 
 +[[https://​www.atsjournals.org/​doi/​pdf/​10.1164/​ajrccm-conference.2018.197.1_MeetingAbstracts.A5081|The Associations of Invasive Procedures and Subsequent Psychiatric Diagnoses]] 
 + 
 +[[https://​www.atsjournals.org/​doi/​abs/​10.1164/​ajrccm-conference.2018.197.1_MeetingAbstracts.A7694 |Obstructive Sleep Apnea Increases the Risk of Diastolic Heart Failure: Results of a Large Population Study ]] 
 + 
 +[[https://​www.abstractsonline.com/​pp8/#​!/​5789/​presentation/​11491|Viral Pneumonia Is an Independent Risk Factor for Pulmonary Fibrosis: Results of Large-Scale Longitudinal Population-Level Data|]] 
 + 
 +[[https://​www.abstractsonline.com/​pp8/#​!/​5789/​presentation/​22530|Platelet Transfusion Is an Independent Risk Factor for Idiopathic Pulmonary Fibrosis: Results of Large-Scale Longitudinal Population-Level Data]]
  
-*** Participants:​ *** 
  
-  * Alireza Aani 
-  * Yalda Aryan 
-  * Menelaos Konstantinidis 
  
 **Repository:​** ​ **Repository:​** ​
projects/workgroups/causal_inference.1574562562.txt.gz · Last modified: 2019/11/24 02:29 by abbas