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research:ldl_vs_statin_intensity

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research:ldl_vs_statin_intensity [2014/12/06 21:30] (current)
jduke created
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 +====== LDL Levels vs Statin Intensity as a Predictor of Adverse Cardiac Events======
  
 +<WRAP box justify round>
 +
 +**Objective:​** The goal of our study is to evaluate practice-based evidence from to determine whether achieved LDL or statin intensity status is most important in predicting adverse health outcomes. ​
 +
 +**Rationale:​** Recommendations from the 2013 American College of Cardiology/​American Heart Association Guidelines on the Assessment of Cardiovascular Risk have had a controversial reception. ​ Questions remain as to whether statins possess an intrinsic beneficial quality above and beyond their reduction of LDL levels, and thus should be maximized regardless of LDL level. ​ Studies are also conflicting as to whether LDL reduction using drugs other than a statin will achieve equivalent results in terms of cardiovascular protection.
 +
 +**Project Lead(s):** Nigam Shah, Jon Duke [others pending]
 +
 +**Coordinating Institution(s):​** Stanford University
 +
 +** Additional Participants:​** ​ //<​usually blank initially, list will grow as individuals are added who are not project leads>//
 +
 +**Full Protocol:** //<if available, a link to protocol. ​ not necessary for initial planning>//​
 +
 +**Initial Proposal Date:​**  ​
 +
 +**Launch Date:​** ​ //<fill out once finalized>//​
 +
 +**Study Closure Date:  //<fill out once finalized>//​**
 +
 +**Results Submission:​** //<​method of sumission, eg. [[mailto:​contact@ohdsi.org|Email]] or SFTP>//
 +
 +</​WRAP>​
 +
 +===== Requirements =====
 +**CDM:** //<V4 or V5 or both>//
 +
 +**Table Accessed:​** ​ //<e.g., person, drug_exposure,​ observations>//​
 +
 +**Database Dialects:** SQL Server, Postgres, Oracle
 +
 +**Software:​** ​ //<<​e.g.,​ R>// ​
 + 
 +===== Code ===== 
 +[[https://​github.com/​OHDSI/​StudyProtocols]]
 +
 +===== Discussion ===== 
 +//Post a thread letting everyone know about this new proposed study at [[http://​forums.ohdsi.org/​c/​researchers]]// ​
 +
 +===== Datasets Run ===== 
 +  * <list your own datasets or leave blank>
 +
 +
 +~~NOTOC~~
research/ldl_vs_statin_intensity.txt ยท Last modified: 2014/12/06 21:30 by jduke