research:risk_of_acute_kidney_injury_between_conventional_nsaids_and_selective_cox-2_inhibitors
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research:risk_of_acute_kidney_injury_between_conventional_nsaids_and_selective_cox-2_inhibitors [2018/01/08 04:06] scyou |
research:risk_of_acute_kidney_injury_between_conventional_nsaids_and_selective_cox-2_inhibitors [2018/01/10 01:55] scyou [Code] |
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| - | ====== < Risk of acute kidney injury between conventional NSAIDs and selective COX-2 inhibitors >====== | + | ====== Risk of acute kidney injury between conventional NSAIDs and selective COX-2 inhibitors ====== |
| <WRAP box justify round> | <WRAP box justify round> | ||
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| Early studies suggested that selective COX-2 inhibitors caused fewer renal adverse effects including reduction in glomerular filtration rate, increased serum creatinine and hypertension. However, other studies have shown no significant differences in renal risk between selective COX-2- inhibitors and conventional NSAIDs. Therefore, the aim of this study is to compare the risk of acute kidney injury between selective COX-2 inhibitor and conventional NSAIDs in the large population. | Early studies suggested that selective COX-2 inhibitors caused fewer renal adverse effects including reduction in glomerular filtration rate, increased serum creatinine and hypertension. However, other studies have shown no significant differences in renal risk between selective COX-2- inhibitors and conventional NSAIDs. Therefore, the aim of this study is to compare the risk of acute kidney injury between selective COX-2 inhibitor and conventional NSAIDs in the large population. | ||
| - | **Project Lead(s):** Ji In Park, MD, Kangwon National University Hospital, Korea | + | **Project Lead(s):** Ji In Park, MD, Kangwon National University Hospital, Korea; |
| Seng Chan You, MD, Ajou University, Korea | Seng Chan You, MD, Ajou University, Korea | ||
| - | **Coordinating Institution(s):** Ajou University | + | **Coordinating Institution(s):** Ajou University; Kangwon National University Hospital |
| ** Additional Participants:** | ** Additional Participants:** | ||
| - | Gacheon Gil hospital | ||
| - | Samsung Medical Center | ||
| **Full Protocol:** | **Full Protocol:** | ||
| - | **Initial Proposal Date:** | + | **Initial Proposal Date:** 8th Jan 2018 |
| - | **Launch Date:** 8th Jan 2018 | + | **Launch Date:** |
| **Study Closure Date: ** | **Study Closure Date: ** | ||
| Line 35: | Line 33: | ||
| **Table Accessed:** person, condition, drug, procedure, measurement | **Table Accessed:** person, condition, drug, procedure, measurement | ||
| - | **Database Dialects:** SQL Server, Postgres, Oracle | + | **Database Dialects:** Any that SqlRender provides |
| **Software:** R | **Software:** R | ||
| ===== Code ===== | ===== Code ===== | ||
| - | [[]] | + | [[https://github.com/OHDSI/StudyProtocolSandbox/tree/master/NSAIDsVsCoxib_AKI]] |
| ===== Discussion ===== | ===== Discussion ===== | ||
research/risk_of_acute_kidney_injury_between_conventional_nsaids_and_selective_cox-2_inhibitors.txt ยท Last modified: 2018/01/10 01:55 by scyou
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