research:project_proposal_template

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research:project_proposal_template [2014/12/06 21:28] – removed jdukeresearch:project_proposal_template [2015/02/16 20:45] (current) – rkboyce
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 +====== Incidence of exposure to drugs for which pre-emptive pharmacogenomic testing is available  ======
  
 +<WRAP box justify round>
 +
 +**Objective:** Derive data that large healthcare organizations can combine data on risks of adverse events  and cost data to conduct cost-effectiveness / cost-benefit analyses for pre-emptive pharmacogenomics testing
 +
 +**Rationale:** Very few studies have been conducted that report on the potential return on investment for pre-emptive pharmacogenomics testing. The studies that have been published  suggest that pre-emptive pharmacogenomics testing may produce a return on investment but much depends on if a sufficient number of drugs with pharmacogenes are covered by a single test. Since the current data are limited to relatively localized settings and might not be of generalizable use to other health organizations, it's of interest to implement a new study using the OHDSI research network. 
 +
 +**Project Lead(s):** Richard D. Boyce, Matthias Samwald, Patrick Ryan, (seeking other collaborators)
 +
 +**Coordinating Institution(s):** University of Pittsburgh, Medical University of Vienna
 +
 +** Additional Participants:**  //<usually blank initially, list will grow as individuals are added who are not project leads>//
 +
 +**Full Protocol:** //<if available, a link to protocol.  not necessary for initial planning>//
 +
 +**Initial Proposal Date:**  2/16/2015
 +
 +**Launch Date:**  //<fill out once finalized>//
 +
 +**Study Closure Date:  //<fill out once finalized>//**
 +
 +**Results Submission:** //<method of sumission, eg. [[mailto:[email protected]|Email]] or SFTP>//
 +
 +</WRAP>
 +
 +===== Requirements =====
 +**CDM:** V4 or V5
 +
 +**Table Accessed:**  DRUG_EXPOSURE, CONCEPT_ANCESTOR, CONCEPT_RELATIONSHIP, PERSON
 +
 +**Database Dialects:** SQL Server, Postgres, Oracle
 +
 +**Software:** SQL and R 
 + 
 +===== Code ===== 
 +[[https://github.com/OHDSI/StudyProtocols/tree/master/Proposed%20Study%203%20-%20Incidence%20of%20exposure%20to%20PGx%20drugs|GitHub code for Proposed Study 3 - Incidence of exposure to PGx drugs]]
 +
 +===== Discussion ===== 
 +//Post a thread letting everyone know about this new proposed study at [[http://forums.ohdsi.org/c/researchers]]// 
 +
 +===== Datasets Run ===== 
 +  * Truven CCAE in the IMEDS lab
 +  * Truven MDCD in the IMEDS lab
 +  * Truven MDCR in the IMEDS lab
 +
 +
 +~~NOTOC~~
research/project_proposal_template.1417901337.txt.gz · Last modified: by jduke

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