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research:treatment_pathways_in_chronic_disease [2014/12/06 21:04] (current)
jduke created
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 +====== Treatment Pathways in Chronic Disease ======
 +
 +<WRAP box justify round>
 +
 +**Objective:​** The objective of this study is to characterize the prevalence of different treatment pathways for three chronic diseases: Hypertension,​ Type II Diabetes, and Depression. ​ We will systematically summarize the treatment pathways observed among patients who have at least 3 years of continuous observation and persistent treatment following initiation. ​ We will stratify the results by year to evaluate temporal trends, and will further stratify by data source to determine if treatment pathways vary by population, geography, and data capture process.
 +
 +**Rationale:​** While numerous treatment guidelines exist for chronic conditions, there is a paucity of data on the real-world treatment pathways that patients experience in practice. Understanding these pathways is essential for establishing context around questions of drug utilization,​ effectiveness,​ and adherence. ​
 +
 +**Project Leads:** Patrick Ryan, Jon Duke, George Hripcsak, Martijn Schuemie, Nigam Shah
 +
 +**Coordinating Institution(s):​** Janssen R&D, Columbia University, Regenstrief Institute, Stanford University
 +
 +** Additional Participants:​**
 +
 +**Full Protocol:** [[https://​dl.dropboxusercontent.com/​u/​505070/​OHDSI%20treatment%20patterns%2030nov2014.docx|Hypertension Treatment Pathways 12-4-2014]]
 +
 +**Initial Proposal Date:​** ​ 12/3/2014
 +
 +**Launch Date:​** ​ 12/5/2014
 +
 +**Study Closure Date:  12/​31/​2014**
 +
 +**Results Submission:​** [[mailto:​contact@ohdsi.org|Email]] or SFTP
 +
 +</​WRAP>​
 +
 +===== Requirements =====
 +**CDM:** V4 or V5
 +
 +**Database Dialect:** SQL Server, Postgres, Oracle
 +
 +**Software:​** ​ SQL as above, R (optional) ​
 + 
 +===== Code ===== 
 +[[https://​github.com/​OHDSI/​StudyProtocols]]
 +
 +===== Discussion ===== 
 +[[http://​forums.ohdsi.org/​t/​ohdsi-study-1-treatment-pathways-in-chronic-disease/​112|Treatment Pathways Discussion Thread]] ​
 +
 +===== Datasets Run ===== 
 +  * Truven
 +  * Optum
 +  * CPRD
 +  * Indiana Network for Patient Care
 +
 +
 +~~NOTOC~~
  
research/treatment_pathways_in_chronic_disease.txt ยท Last modified: 2014/12/06 21:04 by jduke