2019 OHDSI Face-to-Face

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Date/Time
Date(s) - 06/03/2019 - 06/04/2019
8:00 am - 6:00 pm

Location
Case Western Reserve University

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The Cleveland Institute for Computational Biology and Case Western Reserve University is thrilled to announce that they will be hosting the upcoming F2F meeting in Cleveland, OH.

About

What happens when collaborators from across the OHDSI community come together? We run a study!

BUT this time we DOCUMENT every step along the way, so it is a “Doc-A –Thon” basically!

The Goal of this F2F is to generate documentation, produce material to share with the OHDSI community and integrate all of this in “The Book of OHDSI”.

We want to increase the accessibility to the OHDSI tools by providing some kind of “step by step” instructions on how to run a study in the OHDSI community, it’ll look like this:

Step #1: Explore the OHDSI vocabulary
Step #2: Create cohorts
Step #3: Produce negative controls, perform empirical calibration
Step #4: Make the analytic design choices
Step #5: Explore the R packages available and determine the appropriate (Prepare the R package)
Step #6: Run the Cohort characterization
Step #7: Run the Patient Level prediction
Step #8: Run the Population level estimation results
Step #9: Interpret the Cohort characterization results
Step #10: Interpret the Patient Level prediction results
Step #11: Interpret the Population level estimation results
Step #12: Set up a network study

The attendees will be divided into groups responsible for a different step. Within these groups, one part of the attendees will be responsible to execute the step and the other part, in parallel, will be responsible to document the process.

Who Should Attend

Not sure if you should attend? If one of the following statements applies to you, we’d encourage you to register:

  • You are passionate about documentation.
  • You want to contribute to the OHDSI community by creating “Step by Step” documentation material that will be widely shared.
  • You want to learn and dive into the details of how to execute one or more of these steps.
  • You want to document the process.
  • You want to use the OHDSI tools to run the study.
  • You want to be the coordinator of one or more of these steps.
  • You want to share your knowledge with others.
  • You want to visit Cleveland!

Agenda

Sunday, June 2nd 2019
The pre-meeting dinner and talk will be open to all OHDSI members attending the doc-a-thon as well as our partners in Cleveland (University Hospitals Medical Center, Cleveland Clinic Foundation, Metro Health and the Veterans Affairs Louis Stoke Hospital)

Time Description Location
4:00-4:30pm Registration/reception WRB Lobby
4:30-6:00pm OHDSI Community talk by Patrick Ryan and other leaders WRB Auditorium
6:00-7:30pm Buffet dinner and networking WRB Lobby

DAY 1 – Monday, June 3rd 2019
The doc-a-thon will be organized in two sessions: before and after lunch. Each session will be divided in three groups running the study step in parallel. At the end of each day, each of the 6 groups will present their documentation.

Time Description Location
8:30-9:00am Registration/Breakfast WRB Lobby
9:00-9:30am Introductions and Work Plan WRB Auditorium
9:30-12:30pm
  • Group #1: Explore the OHDSI vocabulary – Room WRB 1413
  • Group #2: Create Cohorts – Room WRB 1217
  • Group #3: Incidence Rates – Room WRB 1223A
Meeting Rooms
12:30-1:30pm Lunch WRB 1223A Area
1:30-4:30pm
  • Group #4: Clinical Characterization: Make the analytic design choices, run and interpret results – Room WRB 1413
  • Group #5: Population Level Estimation: Make the analytic design choices, run and interpret results – Room WRB 1217
  • Group #6: Patient Level Prediction: Make the analytic design choices, run and
    interpret results – Room WRB 1223A
Meeting Rooms
5:30-6:30pm
  • Presentation of the documentation (10 minutes each group)
  • Plan for Day 2
WRB Auditorium
6:30pm Dinner WRB 1223A Area

DAY 2 – Tuesday, June 4th 2019

Time Description Location
8:30-9:00am Registration/Breakfast WRB Lobby
9:00-12:00pm
  • Group #4: Clinical Characterization (continued) – Room WRB 1413
  • Group #5: Population Level Estimation (continued) – Room WRB 1217
  • Group #6: Patient Level Prediction(continued) – Room WRB 1223A
Meeting Rooms
12:00-1:00pm Lunch WRB 1223A Area
1:00-3:00pm
  • Group #7: Set up a network study – Room WRB 1413
  • Group #8: ATLAS Design Choice-Decision Tree – Room WRB 1217
Meeting Rooms
3:00-4:00pm Work completed, wrap up and next steps WRB Auditorium

Study Topic

Topic: Hypertension

Specific questions to address:

Phenotype Problems:

  • Find patients who initiate ACE inhibitor monotherapy as first-line treatment for hypertension
  • Find patients who initiate thiazide diuretic monotherapy as first-line treatment for hypertension
  • Find acute myocardial infarction events
  • Find angioedema events Characterization problem:  Compare baseline characteristics (demographics, prior conditions/drugs/procedures) between (a) patients who initiate ACE inhibitor monotherapy as first-line treatment for hypertension and (b) patients who initiate thiazide diuretic monotherapy as first-line treatment for hypertension.

Incidence Problem: 

  • Amongst patients who initiate (a) first-line ACE inhibitor monotherapy or (b) thiazide diuretic monotherapy
  • What proportion will develop (a) acute myocardial infarction, and (b) angioedema in next year following exposure?

Estimation problem:

  • To compare the hazards of (a) acute myocardial infarction and (b) angioedema between the target cohort of patients who initiate first-line ACE inhibitor monotherapy and the comparator cohort of patients who initiate first-line thiazide diuretic monotherapy during the time-at-risk from 1 day after exposure start until end of continuous
    exposure (e.g. ‘on treatment’).

Prediction problem:

  • Amongst patients who initiate first-line ACE inhibitor monotherapy, which go on to develop (a) acute myocardial infarction, and (b) angioedema in next year following exposure?

Directions

The 2019 F2F will take place at Case Western Reserve University, Wolstein Research Building located at 2103 Cornell Rd, Cleveland, OH 44106. Directions are available here:

Directions Directions

Nearby Accommodation

COURTYARD BY MARRIOTT
ADDRESS: 2021 Cornell Road Cleveland, Ohio 44106
PHONE: 216-791-5678
WEBSITE

GLIDDEN HOUSE HOTEL
ADDRESS: 1901 Ford Drive Cleveland, Ohio 44106
PHONE: 215-231-8900
WEBSITE

HOLIDAY INN CLEVELAND CLINIC
ADDRESS: 8650 Euclid Avenue Cleveland, Ohio 44106
PHONE: 216-707-4200
WEBSITE

INTERCONTINENTAL HOTEL & CONFERENCE CENTER
ADDRESS: 9801 Carnegie Avenue Cleveland, Ohio 44106
PHONE: 216-707-4100
WEBSITE

INTERCONTINENTAL SUITES
ADDRESS: 8800 Euclid Avenue Cleveland, Ohio 44106
PHONE: 216-707-4300
WEBSITE

TUDOR ARMS HOTEL
ADDRESS: 10660 Carnegie Avenue Cleveland, Ohio 44106
PHONE: 216-455-1260
WEBSITE

WASHINGTON PLACE BISTRO & INN
ADDRESS: 2203 Cornell Rd Cleveland, OH 44106
PHONE: (216) 791-6500
WEBSITE

Contact

If you have any questions about the hack-a-thon please contact Mark Beno, Paola Saroufim or Wanda Lattimore

Registration

Register Here! Register Here!

This is a working meeting. All in attendance are expected to participate in discussions and contribute their knowledge and skills to each session they attend.

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