April 22, 2025
Two core pillars of OHDSI research—estimation and prediction—took center stage during our April 22 community call. As part of our Analysis April theme, this session highlighted the progress we’re making in real-world evidence generation and showcases the tools and methods driving this work forward.
We were excited to welcome leading voices from both research areas to share updates on current practices and discuss cutting-edge tools developed within the OHDSI community:
- George Hripcsak, Vivian Beaumont Allen Professor of Biomedical Informatics, Columbia University
- Marc Suchard, Professor of Biostatistics, Biomathematics, & Human Genetics, UCLA
- Ross Williams, Assistant Professor, Erasmus University Medical Centre
- Egill Fridgeirsson, Scientific Researcher/Postdoc, Erasmus University Medical Centre
- Jenna Reps, Associate Director, Observational Health Data Analytics, Johnson & Johnson
Community Updates
• Congratulations to the team of Daniel Kapitan, Femke Heddema, André Dekker, Melle Sieswerda, Bart-Jan Verhoeff, and Matt Berg on the recent publication of Data Interoperability in Context: The Importance of Open-Source Implementations When Choosing Open Standards in the Journal of Medical Internet Research.
• Congratulations to the team of Young Hwa Lee, Young June Choe, Yoon Sun Yoon, Ji Young Park, Yun-Kyung Kim, Hyung Joon Joo, Sujin Choi, Hyun Jung Kim and Lorenzo Bertizzolo on the recent publication of Predicting ICU Admission Risk in Children with Respiratory Syncytial Virus in Infectious Diseases and Therapy.
• Congratulations to the team of Jenna Reps, Peter Rijnbeek and Patrick Ryan on the recent publication of Can we develop real-world prognostic models using observational healthcare data? Large-scale experiment to investigate model sensitivity to database and phenotypes in Diagnostic and Prognostic Research.
• The submission deadline for the 2025 Collaborator Showcase is July 1. The showcase will be accepting both posters and software demos, as well as interest in hosting lightning talks. More information on the symposium, including abstract submission and registration links, will be available soon.
• Our fourth annual DevCon will be held Friday, April 25, from 9 am – 2 pm ET. This virtual session continues to connect our global open-source community so that we can learn about recent updates and discuss ways to continue enhancing the future of OHDSI open-source software.
• The Columbia Summer School on OHDSI, which will be held July 14-18 at Columbia University, provides health professionals, researchers, and industry practitioners with an immersive, hands-on training to working with real-world health data and generating real-world evidence (RWE). Participants will explore the types of healthcare data captured during routine clinical care—such as electronic health records and administrative claims—and learn how to standardize these data using the OMOP Common Data Model to support collaborative, distributed research as part of a data network. Registration is now open and will be capped at 30 people.
• Christian Reich and Sarah Seager are leading an effort to publish a second edition of the Book of OHDSI, which will include updates to previous text and new paragraphs/chapters. This work is taking place within the Education workgroup; if you would like to join this effort, please sign up here.
Save The Dates
• The OHDSI Global Symposium will be held Oct. 7-9 at the Hyatt Regency Hotel in New Brunswick, NJ, USA. Agenda and registration information will be shared when available.
• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium.
OHDSI Social Showcase
• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:
Monday — PHederation – the federated network of Pulmonary Hypertension registries (Eva-Maria Didden)
Tuesday — Gap Analysis of Static Automated Perimetry Concept Representation in OMOP CDM (Shahin Hallaj)
Wednesday — Enhancing Cardiovascular Adverse Event Detection in ICI-Treated Cancer Patients: Lessons Learned from Natural Language Processing Integration with OMOP CDM (Clara L. Oeste)
Thursday — Electrocardiogram-Based Identification of Acute Heart Failure in Chronic Heart Failure: A MIMIC-IV and OMOP-CDM Standardized Approach (Seung Wook Lee)
Friday — OHDSI AI: Generative AI-powered Knowledge Translation of OHDSI Research Literature and Singapore’s Cardiovascular Research (Maisie Ng)
Slides
Estimation | Prediction | Community Updates
Videos
Recent Advances in Estimation (Hripcsak, Suchard)
Recent Advances in Prediction (Williams, Fridgeirsson)
