This Week in OHDSI

Nov. 4, 2025

The Nov. 4 community call featured the winners of the Best Community Contribution Honors from the 2025 Global Symposium. Four lead authors presented the work that earned top recognition from their peers across the OHDSI community.

Methods Research: Lu Li (University of Pennsylvania): LATTE: A One-shot Lossless Algorithm for Federated Target Trial Emulation with Application to Alzheimer’s Disease and Related Dementia Drug  Repurposing Using Decentralized Data

Community: Clair Blacketer (Johnson & Johnson): Building the OHDSI Evidence Network – A Global, Open, Federated Collaboration

Data Standards: Jared Houghtaling (Tufts University): OMOP Waveform Extension: A Schema for Integrating Physiological Signals and Derived Features into the OMOP CDM

Clinical Applications: Hsin Yi “Cindy” Chen (Columbia University): Heterogeneity of Treatment Effects Across Nine Glucose-Lowering Drug Classes in Type 2 Diabetes: Extension of the LEGEND-T2DM Network Study

Open-Source Development honoree Adil Ahmed will present his work the following week during the software demo session.

Community Updates

• Congratulations to the team of Sarah B. Floyd, Ashley Mills, Jason Woloff, Christian Lowson, Coleman Hilton, Donna Oeffinger, and Steven Hwang on the recent publication of Development and validation of a computable phenotype for adolescent idiopathic scoliosis in Learning Health Systems.

Congratulations to the team of Han Chang Lim, Howard Wong, Reji Philip, Anton Van Der Vegt, Kim-Kwang Raymond Choo, Jason D. Pole, and Clair Sullivan on the recent publication of Streamlining electronic medical record data extraction and validation in digital hospitals: A systematic review to identify optimal approaches and methods in Learning Health Systems.

• Congratulations to the team of Gucheol Jung, JaeHyeok Lee, Sung-Min Gho, YoungMi Han, ByungKwan Choi, Jae Wook Cho, Jiyoung Kim, and Gha-hyun Lee on the recent publication of Predicting oxcarbazepine-induced hyponatremia in adult epilepsy patients: A multicenter machine learning analysis using real-world CDM data in Seizure: European Journal of Epilepsy.

• Congratulations to the team of Nadav Rappoport, Guy Livne, Naama Perry Cohen, Nir Makover, Hadas Eshel-Geva, Hadar Kapach, Tomer Hadad, Yarin Alon, Robyn Rubin, Segev Chai, Shirell da Villa, and Ohad Hochman on the recent publication of Kineret: Israel’s Largest Hospital Network Transformed into the OMOP common data model for collaborative research in PLOS One.

• The latest edition of the OHDSI newsletter is now available. This edition includes materials from the 2025 Global Symposium (videos, slides, posters), the 2025 edition of the Our Journey booklet, a collaborator spotlight Q&A with Andrew Kanter, recent community updates, publications and presentations from October, and plenty more.

• The latest “On The Journey” annual report is now on the OHDSI homepage. This 134-page PDF provides an overview of the OHDSI community, including a look at its collaborators and collaborative activities, its research areas and tools, its work with standardized data and vocabularies, and nearly 900 publications that have come from the community.

• Registration is now open for the 2026 Summer School in Observational Health Data Science & Informatics, AI, and Real World Evidence, which will be held June 22-26 at the Columbia University Department of Biomedical Informatics. Now in its second-year, the Columbia OHDSI Summer School provides health professionals, researchers, and industry practitioners with an immersive, hands-on training to working with real-world health data and generating real-world evidence (RWE). Participants will explore the types of healthcare data captured during routine clinical care—such as electronic health records and administrative claims—and learn how to standardize these data using the OMOP Common Data Model to support collaborative, distributed research as part of a data network.

• There is a new tutorials homepage on OHDSI.org that hosts all tutorials from past Global/US Symposia, as well as tutorials from the SOS Challenge. Future tutorials will also be added here.

• A scholarship honoring the late Jamie Weaver has been created at the University of Oxford, and applications are now being accepted. This 3-year PhD funded studentship will focus on ‘Improving the quality of real world evidence by measuring and minimising outcome misclassification using the OMOP common data model and large multinational health data,’ research that Weaver was leading during his time as a PhD trainee at Oxford. More information and application details are available here.

Job Openings

• Erasmus MC recently posted job openings for both a Health Data Scientist and a PhD student in medical informatics. More details and an application link are available on the respective pages. The closing date for both positions is Nov. 17.

Save The Dates

• The first-ever 2025 OHDSI Africa Symposium will be held Nov. 10-12 in Kampala, Uganda, and registration is open. A tentative agenda has been posted on the event homepage.

• The 2025 OHDSI Asia-Pacific Symposium will be held Dec. 6-7 in Shanghai, China. Registration is open, and agenda details will be shared when available.

OHDSI Social Showcase

• Research from the 2025 Europe Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X, Instagram and Bluesky feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — The DARWIN EU® Data Network (Maxim Moinat)
Tuesday — Incidence Rates of Suicidality Related Events in Patients with Chronic Skin Conditions of Acne and Psoriasis in the European Population (Marzyeh Amini)
Wednesday — Adoption of the OMOP CDM for Cancer Research: A prostate cancer use-case (Manos Hatzakis)
Thursday — Temporal and Regional Trends in Curative and Palliative Systemic Anticancer Treatments for Aging Populations: A Transatlantic Analysis of the Ten Most Incident Cancers (Linnea Schumann)
Friday — Amyloid Cardiomyopathy Community Uptake of Recommended Assessment and Testing Efforts (ACCURATE Study): A Large-Scale Data Analysis Using an Algorithm-Goes-to-Data (Clara Teixeira)

Slides

Community Updates

Video Presentations

OMOP Waveform Extension: A Schema for Integrating Physiological Signals and Derived Features into the OMOP CDM (Houghtaling)

LATTE: A One-shot Lossless Algorithm for Federated Target Trial Emulation with Application to Alzheimer’s Disease and Related Dementia Drug Repurposing Using Decentralized Data (Li)

Heterogeneity of Treatment Effects Across Nine Glucose-Lowering Drug Classes in Type 2 Diabetes: Extension of the LEGEND-T2DM Network Study (Chen)

Building the OHDSI Evidence Network – A Global, Open, Federated Collaboration (Blacketer)