This Week in OHDSI

June 9, 2026

Generative AI and Large Language Models (LLMs) have the potential to massively accelerate our research mission, and we are seeing incredible breakthroughs across our global community. Our June 9 community call held the second of a special three-part series dedicated to LLM research in OHDSI:

  • FastOMOP – multi agent cohort creation(Niko Moeller-Grell, King’s College)
  • Phenelope – tool for developing concept sets using LLM (Joel Swerdel, Johnson & Johnson)
  • LLM-Based Phenotype Refinement via CAPR (Jared Houghtaling, Johnson & Johnson)
  • Using Synthetic Data and Claude Code to Develop Transportable Analytic Code (Adam Johnson, Duke University)

Community Updates

• Thank you to everybody who submitted brief reports to take part in the 2026 Global Symposium. It was another record-breaking year, as we received more than 170 submissions. Early thanks also go to the members of our Scientific Review Committee, who will read of the submissions over the next month.

• Congratulations to the team of Hyejin Hong, Soyeon Kim, and Borim Ryu on the recent publication of Enhancing multimodal inpatient fall prediction via nursing statement integration within the OMOP common data model in Scientific Reports.

• Congratulations to the team of Cindy X Cai, Brian Toy, Benjamin Martin, Ruochong Fan, Erik Westlund, Diep Tran, Akihiko Nishimura, Haeun Lee, Theodore Leng, Paul Nagy, Nestoras Mathioudakis, Linying Zhang, Michelle Hribar, Aiyin Chen, Karen Armbrust, Kerry Goetz, Sally Baxter, Michael V Boland, Eric N Brown, Edmund Tsui, Andrew J Barkmeier, Sophia Wang, Nitish Mehta, Jacqueline C Stocking, Ghazala O’Keefe, Cecilia S Lee, Philip R O Payne, William J O’Brien, Scott DuVall, Thamir Alshammari, Thomas Falconer, David A Dorr, Izabelle Humes, David McCoy, Mohammed Adibuzzaman, Rumel Mahmood, Hannah Morgan-Cooper, Priya Desai, Shikha Yashwant Kothari, Anthony Sena, Clair Blacketer, Anna Ostropolets, Azza Shoaibi, Gowtham Rao, George Hripcsak, Patrick Ryan, and Marc A Suchard on the recent publication of Semaglutide and Neovascular Age-Related Macular Degeneration Among Adults with Type 2 Diabetes: An OHDSI Network Study in Ophthalmology.

A new call for papers is open for a Journal of Biomedical Informatics special issue focusing on agentic AI for generating trustworthy Real-World Evidence (RWE). The issue seeks contributions on multi-agent collaboration and coordinated autonomy across the RWE lifecycle—such as data harmonization and causal analysis—while excluding single-task AI agents. Submissions are accepted from June 15 through November 15, 2026, with publication slated for September 2027.

• In a recent week-long collaboration, OHDSI partnered with the Uppsala Monitoring Center (UMC)—the WHO Collaborating Centre for International Drug Monitoring—to help integrate Sweden’s national registry data into the OMOP Common Data Model. Utilizing OHDSI tools and data quality packages, the team successfully designed and executed a full study using Strategus in just five days. This achievement highlights the incredible speed and efficiency of the OMOP CDM when onboarding new data partners to advance global pharmacovigilance.

• The latest edition of The Journey newsletter is now available. It includes a look at the LLM research presentations coming this month, OHDSI’s work with the Uppsala Monitoring Center (UMC) to help integrate Sweden’s national registry data into the OMOP Common Data Model, upcoming community events, spotlights on Anthony Sena and Benjamin Martin, nearly 30 May publications and more. If you don’t receive the newsletter in your inbox, you can subscribe here.

The FALCON (Federated Alliance for Large-scale Cancer Observational Network) Research Network is dedicated to advancing real-world oncology evidence through federated health analyses. The network is hosting its 2026 Symposium and Bladder Cancer Studyathon from Sep. 28-Oct. 1 at Dunden in Antwerp, Belgium. This intensive four-day event kicks off with a general symposium followed by a three-day collaborative working session for researchers, clinicians, and data scientists to generate high-quality clinical evidence on the OMOP CDM.

• Take your OMOP CDM from implementation to impact with The OMOP Practitioner, an intensive three-day expert training hosted Sept. 7-9 by Erasmus MC in Rotterdam. Registration is now OPEN.  This hands-on program moves beyond the basics, offering a maximum of 30 participants deep-dive experience with the Data Quality Dashboard, ATLAS, and real-world study execution.

Upcoming Events

• The first OHDSI Latin America Symposium will be held July 30-31 in Salvador, Brazil. The event will include multiple workshops, including sessions focused on Introduction to OMOP, Cohort building, ETL for OMOP, and Scientific collaboration: opportunities for network studies in Latin America.

• The UK Symposium will be held September 18 at the University of Nottingham, preceded by an OMOP Training Day on September 17.

Registration and the call for participation are now open for the 2026 OHDSI Global Symposium, held Oct. 20–22 at the Hyatt Regency in New Brunswick, N.J. You can also read more about our 12 new tutorial offerings and workgroup activities which will take place during the event. The deadline to submit your brief reports for the Collaborator Showcase is June 5 at 8 pm ET.

Social Showcase

• Research from the 2026 Europe Symposium Collaborator Showcase is being shared daily on OHDSI’s LinkedIn, Twitter/X, Instagram and Bluesky social channels as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — From Tool Zoo to FAIRified Pipeline: Evaluating Terminology and Mapping Tooling for the SHINe Platform (Karen Triep)
Tuesday — Mitos: A Python implementation of OHDSI Circe cohort expressions with schema fidelity and cross-engine validation (Egill Fridgeirsson)
Wednesday — Extending OMCP to the OHDSI Application Layer: MCP Servers for Vocabulary, Cohort Definition, and Statistical Profiling (Niko Möller-Grell)
Thursday — From OHDSI Cohorts to Trustworthy, Reproducible and Reusable Dashboards for your Enterprise (Lisa Murch)
Friday — Using coding agents and a skill-based context engineering approach to map EMA authorized drugs to RxNorm (Rowan Parry)

Slides

Swerdel | Houghtaling | JohnsonCommunity Updates

Video Presentations

FastOMOP – multi agent cohort creation

https://youtu.be/TW2dpFdYHP8

Phenelope – tool for developing concept sets using LLM

https://youtu.be/nsjIC6GxlrM

LLM-Based Phenotype Refinement via CAPR

https://youtu.be/e0IoiEKfwow

Using Synthetic Data and Claude Code to Develop Transportable Analytic Code

https://youtu.be/Svzae5wq7SA