Games, gratitudes and an OHDSI version of Christmas Carol-oke were all part of our annual holiday-themed final call of the year! Thank you to everybody in the community for your hard work and camaraderie in 2022. Community calls will resume Jan. 10, 2023. Happy holidays!

Updates

• Congratulations to the OHDSI community in 2022, which set records with 111 publications by 2,057 cumulative authors. You can find all studies from 2022 and before in our publications dashboard, one of the new options in our new community dashboard developed by Paul Nagy and his team this year!

• Thamir AlShammary, an advisor to the President of the Saudi Food and Drug Authority (SFDA), has been an active contributor to the OHDSI community for several years. He collaborates in several workgroups, including Population-Level Estimation, Health Equity and the recently-completed Vaccine Evidence WG, and has been a contributor in several important network studies. He discusses his background, his journey into OHDSI and the impact he has seen, and why OHDSI can be a difference maker in generating trustworthy evidence, tools and best practices within the community, in the latest edition of the Collaborator Spotlight.

• Patrick Ryan introduced the OMOP Common Data Model (CDM) Entity-Relationship Diagram (ERD) Challenge on the forums in November, and announced the two winners during the community call:
Printable: Renke Los (see submission)
Interactive: Vishnu Vardhan Chandrabalan (see submission)

• The EHDEN Consortium announced Monday that 22 data partners from across 13 countries have been selected from the final open call to join the EHDEN data network. The data partners from this call represent almost 200 million patient records, originating from various care settings, adding to the approximately 630 million records with the 166 partners working with EHDEN from the prior six calls.

• The next OHDSI community call will be Jan. 10. You will receive a new call invite after the start of 2023.

OHDSI Social Showcase

• The #OHDSISocialShowcase continues this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Leveraging Location Data in OMOP to Incorporate Area Deprivation Index (Xinzhuo Jiang)
Tuesday: Developing objective metrics to diagnose PatientLevelPrediction model designs (Jenna Reps)
Wednesday: ODAP-B: A One-shot Distributed Algorithm for Modified Poisson Regression for Prospective Studies with Binary Data (Lu Li)
Thursday: Characterization of Health by OHDSI Asia-Pacific chapter to identify Temporal Effect of the Pandemic for Cardiovascular Diseases (CHAPTER-CVDs) (Seng Chan You)
Friday: A Pilot Characterization Study Assessing Health Equity in Mental Healthcare Delivery within the State of Georgia (Jacob Zelko)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

• The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Video Presentation

During the Dec. 13 community call, Patrick Ryan presented a comprehensive look back at the activities, publications, open-source developments and more from the OHDSI community throughout 2022. 

Updates

• Congratulations to the team of Seng Chan You, Seongwon Lee, Byungjin Choi, and Rae Woong Park on the publication of Establishment of an International Evidence Sharing Network Through Common Data Model for Cardiovascular Research in Korean Circulation Journal.

• Congratulations to the team of Ki-Yeol Park, Min-Ho Kim, Seong-Ho Choi, and Eun-Kyoung Pang on the publication of Association of periodontitis with menopause and hormone replacement therapy: a hospital cohort study using a common data model in the Journal of Periodontal and Implant Science.

• Congratulations to Noémie Elhadad, who was selected to serve as the next chair of the Department of Biomedical Informatics (DBMI) at Columbia University. DBMI is the coordinating center for the OHDSI community. Noémie has been a long-time collaborator within the OHDSI community; she was a panelist for the Women in Real-World Analytics Leadership Forum during the 2019 Symposium, she discussed HERA, a Large-Scale Characterization of Health Equity study, during the 2020 Symposium plenary, and recently led a breakout discussion on maternal health research during a May 2022 community call.

• Patrick Ryan introduced the OMOP Common Data Model (CDM) Entity-Relationship Diagram (ERD) Challenge on the forums recently. All members of the OHDSI community are welcome and encouraged to submit their entries of the best ERD for the OMOP CDM to this forum post (or to the CDM Workgroup MS Teams site) by Tuesday, Dec 13. One winner will be selected by a committee from the CDM workgroup, and announced on OHDSI’s last community call of the year on Dec 20.

OHDSI Social Showcase

• The #OHDSISocialShowcase continues this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Cancer Phenotyping Pitfalls in EHR: The case of Non-Small Cell Lung Cancer (Asieh Golozar)
Tuesday: Real World Challenges to Using Real World Data: Creating a Multi-Institutional Database in OMOP (Michael Cantor)
Wednesday: Development of an automated comparator ranking algorithm for the REWARD initiative (Justin Bohn)
Thursday: Healthcare utilization following SARS-CoV-2 infection in children and adolescents with chronic conditions: An EHR-based Cohort Study from the RECOVER Program (Nathan Pajor)
Friday: Standardizing Knowledge of Drug Effects: An Application of PheKnowLator for Drug Safety (Tiffany Callahan)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

• The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Year In Review | Community Updates

Videos

Year In Review (Patrick Ryan)

The Dec. 6 community call featured presentations on five recent publications that came out of our community:

• Integrating real-world data from Brazil and Pakistan into the OMOP common data model and standardized health analytics framework to characterize COVID-19 in the Global South – Sara Khalid (University Research Lecturer, Senior Research Fell in Biomedical Data Science and Health Informatics, University of Oxford)
• Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from five European countries and the US – Xintong Li (PhD student, University of Oxford)
• Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond – Václav Papež (Research Associate, UCL Institute of Health Informatics)
• Adjusting for indirectly measured confounding using large-scale propensity score – Linying Zhang (PhD student, Columbia University)
• PheValuator 2.0: Methodological improvements for the PheValuator approach to semi-automated phenotype algorithm evaluation – Joel Swerdel (Associate Director of Epidemiology Analytics, Janssen Research and Development)

Updates

• Congratulations to the team of Veronika Pav, Andrew Burns, Courtney Colahan, Brian Robison, Jacob Kean, and Scott DuVall on the publication of Illustration of Continuous Enrollment and Beneficiary Categorization in DoD and VA Infrastructure for Clinical Intelligence in Military Medicine.

• Congratulations to the team of Berta Raventós, Alicia Abellan, Andrea Pistillo, Carlen Reyes, Edward Burn, and Talita Duarte-Salles on the publication of Impact of the COVID-19 pandemic on eating disorders diagnoses among adolescents and young adults in Catalonia: A population-based cohort study in the International Journal of Eating Disorders.

• Congratulations to the team of Edward Burn, Elena Roel, Andrea Pistillo, Sergio Fernández-Bertolín, Maria Aragón, Berta Raventós, Carlen Reyes, Katia Verhamme, Peter Rijnbeek, Xintong Li, Victoria Y. Strauss, Daniel Prieto-Alhambra, and Talita Duarte-Salles on the publication of Thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in Catalonia, Spain in Nature Communications.

• Congratulations to the team of Edward Burn, Xintong Li, Antonella Delmestri, Nathan Jones, Talita Duarte-Salles, Carlen Reyes, Eugenia Martinez-Hernandez, Edelmira Marti, Katia M. C. Verhamme, Peter R. Rijnbeek, Victoria Y. Strauss, and Daniel Prieto-Alhambra on the publication of Thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in the United Kingdom in Nature Communications.

• Congratulations to Anna Ostropolets, who successfully defended her dissertation at Columbia University last week. Her dissertation title was “Generating Reliable and Responsive Observational Evidence: Reducing Pre-analysis Bias.”

• George Hripcsak announced that the OHDSI community received a grant from the Chan Zuckerberg Initiative titled, “Open source ontologies to power an open science community.” OHDSI has a vocabulary to support international research, and it is already freely available; this grant expands its development and maintenance from a commercial group to the entire community.

• If you missed the symposium plenary session on Objective Diagnostics: A pathway to provably reliable evidence, or if you wanted to engage in a discussion about the content, please join our OHDSI2022 Plenary Discussion on Friday, Dec. 9, from 10 am – 12 pm ET. We will rewatch the video in sections and take breaks to engage in Q&A with presenters and other collaborators involved in the work. Click here for the meeting link.

• The latest edition of OHDSI’s official newsletter, The Journey, is now available. It includes information on recent open-source developments, the OHDSI APAC Symposium, recent publications and presentations, and other community updates. If you don’t get the newsletter monthly in your inbox, you can subscribe here.

• Patrick Ryan introduced the OMOP Common Data Model (CDM) Entity-Relationship Diagram (ERD) Challenge on the forums recently. All members of the OHDSI community are welcome and encouraged to submit their entries of the best ERD for the OMOP CDM to this forum post (or to the CDM Workgroup MS Teams site) by Tuesday, Dec 13. One winner will be selected by a committee from the CDM workgroup, and announced on OHDSI’s last community call of the year on Dec 20.

OHDSI Social Showcase

• The #OHDSISocialShowcase continues this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: An Evaluation of the Impact of Vocabulary Evolution on Established Phenotypes (Frank DeFalco)
Tuesday: Transitioning ANANKE to OMOP2OBO for more robust NLP extraction and knowledge graph data representation leveraging the OHDSI vocabulary (Juan Banda)
Wednesday: Building organizational capacity for observational research within a health system (Mary Grace Bowring)
Thursday: Topic Modeling of Clinical Notes for Patients with Infectious Disease using Latent Dirichlet Allocation after Deidentification of Protected Health Information (Junhyuk Chang
Friday: ohdsitargets – An R package for building OHDSI study pipelines using targets (Adam Black)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

• The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Khalid | Li | Papez | Swerdel | Community Updates

Videos

Integrating real-world data from Brazil and Pakistan into the OMOP common data model and standardized health analytics framework to characterize COVID-19 in the Global South (Sara Khalid)

Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from five European countries and the US (Xintong Li)

Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond (Václav Papež)

Adjusting for indirectly measured confounding using large-scale propensity score (Linying Zhang) 

PheValuator 2.0: Methodological improvements for the PheValuator approach to semi-automated phenotype algorithm evaluation (Joel Swerdel) 

The Nov. 29 community call featured our final workgroup updates of 2022. We heard about four of our community workgroups from the following collaborators:

Medical Devices • Asiyah Lin (Data and Technology Advancement Scholar, NIH)
Clinical Trials • Tom Walpole (Chief Technology Officer, Trials.ai)
Psychiatry • Dmitry Dymshyts (Associate Director, Janssen R&D)
Patient-Level Prediction • Jenna Reps (Director, Janssen R&D) 

Updates

• Congratulations to the team of Nigel Hughes, Peter Rijnbeek, Kees van Bochove, Talita Duarte-Salles, Carl Steinbeisser, David Vizcaya, Dani Prieto-Alhambra, and Patrick Ryan on the publication of Evaluating a novel approach to stimulate open science collaborations: a case series of “study-a-thon” events within the OHDSI and European IMI communities in JAMIA.

• The EMA has selected the first 10 data partners to collaborate with DARWIN EU^®, the Data Analysis and Real-World Interrogation Network. The data available to these partners will be used for studies to generate real-world evidence that will support scientific evaluations and regulatory decision making, and all have already been mapped to the OMOP CDM. You can learn more about how OHDSI is collaborating with DARWIN EU®.

• The next OHDSI APAC Community Call will be Dec. 1 (Nov. 30 in the Western Hemisphere) and will recap the APAC Symposium. You can join these bi-weekly community calls here.

• Dmytry Dymshyts introduced a charity opportunity to provide Christmas gifts to Ukrainian children on the OHDSI forums. If you are interested to learn more, please check out this post.

• Patrick Ryan introduced the OMOP Common Data Model (CDM) Entity-Relationship Diagram (ERD) Challenge on the forums recently. All members of the OHDSI community are welcome and encouraged to submit their entries of the best ERD for the OMOP CDM to this forum post (or to the CDM Workgroup MS Teams site) by Tuesday, Dec 13. One winner will be selected by a committee from the CDM workgroup, and announced on OHDSI’s last community call of the year on Dec 20.

• Anna Ostropolets will defend her dissertation at Columbia University on Wed., Nov. 30, with an open session scheduled for 10 am ET (join that session here). Her dissertation title is “Generating Reliable and Responsive Observational Evidence: Reducing Pre-analysis Bias.”

• Rupa Makadia was the latest guest to join the Early-Stage Researchers Career Speaker Series. You can watch that discussion here. The next session will be held Monday, Dec. 12 (11 am ET), and Kristin Kostka will be the featured speaker. You can join the call at https://bit.ly/OHDSILeaders.

OHDSI Social Showcase

• The #OHDSISocialShowcase continues this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Machine Learning to Predict the Ischemic Stroke among Type 2 Diabetes Mellitus Patients using Taipei Medical University Clinical Research Database (Phan Thanh Phuc)
Tuesday: Examining Differences in Baseline Characteristics of Broad and Narrow Phenotype Algorithms (Jill Hardin)
Wednesday: OMOP and FHIR Data Comparison (Spencer SooHoo)
Thursday: Analyzing the Use of Beers Criteria Guidelines through ATLAS Operationalization (Richard Boyce)
Friday: Cohort Definition Validation in Atlas (Charity Hilton)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

• The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Clinical Trials | Psychiatry | Community Updates

Videos

Medical Devices (Asiyah Lin)

Clinical Trials (Tom Walpole)

Patient-Level Prediction (Jenna Reps)

Psychiatry (Dmytry Dymshyts)

The Nov. 22 community call featured another of our popular “10-Minute Tutorial” sessions. Five of our community leaders in open-source software development will provide quick tutorials on tools that you can use for your research:

PHOEBE 2.0 • Anna Ostropolets (PhD Student, Columbia University)
Automated Comparator Selection • Justin Bohn (Associate Director, Epidemiology at Janssen)
Strategus • Anthony Sena (Associate Director, Observational Health Data Analytics at Janssen)
Einstein-ATLAS • Selvin Soby (Director, Informatics & Data Analytics at Montefiore)
Broadsea • Lee Evans (Founder, LTS Computing LLC)

Updates

• Congratulations to the team of Yuan Peng, Elisa Henke, Ines Reinecke, Michéle Zoch, Martin Sedlmayr, and Franziska Bathelt on the publication of An ETL-process design for data harmonization to participate in international research with German real-world data based on FHIR and OMOP CDM in the International Journal of Medical Informatics.

• Congratulations to the team of Yerim Kim, Seung In Seo, Kyung Joo Lee, Jinseob Kim, Jong Jin Yoo, Won-Woo Seo, Hyung Seok Lee, Woon Geon Shin on the publication of Long-term use of proton-pump inhibitor on Alzheimer’s disease: a real-world distributed network analysis of six observational Korean databases using a Common Data Model in Therapeutic Advances in Neurological Disorders.

• Patrick Ryan introduced the OMOP Common Data Model (CDM) Entity-Relationship Diagram (ERD) Challenge on the forums recently. All members of the OHDSI community are welcome and encouraged to submit their entries of the best ERD for the OMOP CDM to this forum post (or to the CDM Workgroup MS Teams site) by Tuesday, Dec 13. One winner will be selected by a committee from the CDM workgroup, and announced on OHDSI’s last community call of the year on Dec 20.

• Anna Ostropolets will defend her dissertation at Columbia University on Wed., Nov. 30, with an open session scheduled for 10 am ET (join that session here). Her dissertation title is “Generating Reliable and Responsive Observational Evidence: Reducing Pre-analysis Bias.”

• Rupa Makadia was the latest guest to join the Early-Stage Researchers Career Speaker Series. You can watch that discussion here. The next session will be held Monday, Dec. 12 (11 am ET), and Kristin Kostka will be the featured speaker. You can join the call at https://bit.ly/OHDSILeaders.

OHDSI Social Showcase

• The #OHDSISocialShowcase begins this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Incidence analysis and prediction of potentially harmful drugs among asthma patients (Victor Pera)
Tuesday: Development of the Medical Imaging Extension for OMOP-CDM (Briana Malik)
Wednesday: A survey of OMOP CDM-compatible visualization tools & what the community may do to support tool development and adoption (Natthawut Adulyanukosol)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

• The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org. 

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Strategus | Community Updates

Videos

Automated Comparator Selection (Justin Bohn)

PHOEBE 2.0 (Anna Ostropolets)

Strategus (Anthony Sena)

Einstein-ATLAS (Selvin Soby)

Broadsea (Lee Evans)

The Nov. 15 community call featured some network studies happening within our community, as well as an ARES Software Demo from the OHDSI Symposium.

We heard about these studies from the following leads:

Expanding maternal and infant data from EHRs for pregnancy research
• Safety and Effectiveness of Anti-Hypertensive Medications in Pregnancy
• Project to Characterize Anti-Hypertensive, Anti-Coagulant, Anti-Diabetic and Antibiotic Medication Usage During Pregnancy and Postpartum

Alison Callahan (Instructor, Medicine • Stanford University)
Stephanie Leonard (Instructor, Obstetrics & Gynecology • Stanford University)
Louisa Smith (Assistant Professor, Health Sciences • Northeastern University)

Relative Risk of Cervical Neoplasms Associated with Copper and Levonorgestrel Secreting Intrauterine Devices: Real World Evidence from the OHDSI Network

Matthew Spotnitz (Postdoctoral Research Fellow • Columbia University)

Updates

• Congratulations to the team of Emily Jefferson, Christian Cole, Shahzad Mumtaz, Sam Cox, Tom Giles, Samuel Adejumo, Esmond Urwin, Daniel Lea, Calum Macdonald, Joseph Best, Erum Masood, Gordon Milligan, Jenny Johnston, Scott Horban, Ipek Birced, Christopher Hall, Aaron S Jackson, Clare Collins, Sam Rising, Charlotte Dodsley, Jill Hampton, Andrew Hadfield, Roberto Santos, Simon Tarr, Vasiliki Panagi, Joseph Lavagna, Tracy Jackson, Antony Chuter, Jillian Beggs, Magdalena Martinez-Queipo, Helen Ward, Julie von Ziegenweidt, Frances Burns, Joanne Martin, Neil Sebire, Carole Morris, Declan Bradley, Rob Baxter, Anni Ahonen-Bishopp, Amelia Shoemark, Ana M Valdes, Benjamin Ollivere, Charlotte Manisty, David Eyre, Stephanie Gallant, George Joy, Andrew McAuley, David W Connell, Kate Northstone, Katie Jeffery, Emanuele Di Angelantonio, Amy McMahon, Mat Walker, Malcolm Gracie Semple, Jessica Mai Sims, Emma Lawrence, Bethan Davies, John Kenneth Baillie, Ming Tang, Gary Leeming, Linda Power, Thomas Breeze, Natalie Gilson, Paul Smith, Duncan Murray, Chris Orton, Iain Pierce, Ian Hall, Shamez Ladhani, Matthew Whitaker, Laura Shallcross, David Seymour, Susheel Varma, Gerry Reilly, Andrew Morris, Susan Hopkins, Aziz Sheikh, and Philip Quinlan on the publication of CO-CONNECT: A hybrid architecture to facilitate rapid discovery and access to UK wide data in the response to the COVID-19 pandemic in the Journal of Medical Internet Research.

• The 2022 Asia-Pacific (APAC) Symposium was held Nov. 12-13 at the Taipei Medical University in Taiwan. There were both in-person and remote components to this event, including tutorials on Nov. 12 and the main conference on Nov. 13. Thank you to our APAC leadership team for putting together this event.

• Videos and slides from both the main day and the full-day tutorial at the 2022 OHDSI Symposium have now been posted.

• Do you represent a healthcare system that has adopted OMOP? The Healthcare Systems Interest Group is gathering evidence to support additional healthcare systems’ adoption decisions, and the workgroup wants to hear about the benefits your organization has realized. Please take this survey!

OHDSI Social Showcase

• The #OHDSISocialShowcase begins this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Deployment of an OMOP CDM-compatible NLP system for Rapid Development and Dissemination of a Long-COVID Extraction NLP task (Andrew Wen
Tuesday: Impact of random oversampling and random undersampling on the development and validation of prediction models using observational health data (Cynthia Yang)
Wednesday: Building Korean NER models for a manually annotated corpus from clinical notes using cross-lingual transfer learning (Jianfu Li)
Thursday: Protocol for finding supplemental oxygen data in electronic health record (EHR) flowsheets for inclusion in the OMOP ETL (Tanner Zhang)
Friday: COVID-19 Vaccine Administration Pathways in US Administrative Claims (Kevin Haynes)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

• The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Community Updates | Callahan/Smith/Leonard Slides

Videos

Expanding maternal and infant data from EHRs for pregnancy research (Alison Callahan, Stephanie Leonard, Louisa Smith)

Relative Risk of Cervical Neoplasms Associated with Copper and Levonorgestrel Secreting Intrauterine Devices: Real World Evidence from the OHDSI Network (Matthew Spotnitz)

Software Demo: ARES (Frank DeFalco)

The Nov. 8 community call featured research from the 2022 OHDSI Symposium. The four recipients of the Best Community Contribution Awards were invited to present their research during this session. The honorees were:

Data Standards: Analyzing the Effect of Hypertension on Retinal Thickness Using Radiology Common Data Model (R-CDM) (Chul Hyoung Park, Rae Woong Park, Sang Jun Park, Da Yun Lee, Seng Chan You, Ki Hwang Lee)

Methodological Research: Assessing Racial Fairness of Dialysis Allocation in End-Stage Renal Disease (Linying Zhang, Lauren R. Richter, David M. Blei, Yixin Wang, Anna Ostropolets, Noemie Elhadad, George Hripcsak)

Open-Source Analytics: Cohort Definition Validation in Atlas (Charity Hilton, Saul Crumpton, Jon Duke) * – unable to present during session

Clinical Applications: A Pilot Characterization Study Assessing Health Equity in Mental Healthcare Delivery within the State of Georgia (Jacob Zelko, Malina Hy, Varshini Chinta, Emily Liau, Morgan Knowlton, Jon Duke)

Updates

• Congratulations to the team of Wallis C.Y. Lau, Carmen Olga Torre, Kenneth K.C. Man, Henry Morgan Stewart, Sarah Seager, Mui Van Zandt, Christian Reich, Jing Li, Jack Brewster, Gregory Y.H. Lip, Aroon D. Hingorani, Li Wei, and Ian C.K. Wong on the publication of Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation in Annals of Internal Medicine.

• Congratulations to the team of Xiao Wang, Wenwang Rao, Xueyan Chen, Xinqiao Zhang, Zeng Wang, Xianglin Ma, Qinge Zhang on the publication of The sociodemographic characteristics and clinical features of the late-life depression patients: results from the Beijing Anding Hospital mental health big data platform in BMC Psychiatry.

• Congratulations to the team of Emily Jefferson, Christian Cole, Shahzad Mumtaz, Sam Cox, Tom Giles, Samuel Adejumo, Esmond Urwin, Daniel Lea, Calum Macdonald, Joseph Best, Erum Masood, Gordon Milligan, Jenny Johnston, Scott Horban, Ipek Birced, Christopher Hall, Aaron S Jackson, Clare Collins, Sam Rising, Charlotte Dodsley, Jill Hampton, Andrew Hadfield, Roberto Santos, Simon Tarr, Vasiliki Panagi, Joseph Lavagna, Tracy Jackson, Antony Chuter, Jillian Beggs, Magdalena Martinez-Queipo, Helen Ward, Julie von Ziegenweidt, Frances Burns, Joanne Martin, Neil Sebire, Carole Morris, Declan Bradley, Rob Baxter, Anni Ahonen-Bishopp, Amelia Shoemark, Ana M Valdes, Benjamin Ollivere, Charlotte Manisty, David Eyre, Stephanie Gallant, George Joy, Andrew McAuley, David W Connell, Kate Northstone, Katie Jeffery, Emanuele Di Angelantonio, Amy McMahon, Mat Walker, Malcolm Gracie Semple, Jessica Mai Sims, Emma Lawrence, Bethan Davies, John Kenneth Baillie, Ming Tang, Gary Leeming, Linda Power, Thomas Breeze, Natalie Gilson, Paul Smith, Duncan Murray, Chris Orton, Iain Pierce, Ian Hall, Shamez Ladhani, Matthew Whitaker, Laura Shallcross, David Seymour, Susheel Varma, Gerry Reilly, Andrew Morris, Susan Hopkins, Aziz Sheikh, and Philip Quinlan on the publication of CO-CONNECT: A hybrid architecture to facilitate rapid discovery and access to UK wide data in the response to the COVID-19 pandemic in the Journal of Medical Internet Research.

• Congratulations to the team of Tianchu Lyu, Chen Liang, Jihong Liu, Berry Campbell, Peiyin Hung, Yi-Wen Shih, Nadia Ghumman, Xiaoming Li, and members of the National COVID Cohort Collaborative Consortium on the publication of Temporal Events Detector for Pregnancy Care (TED-PC): A rule-based algorithm to infer gestational age and delivery date from electronic health records of pregnant women with and without COVID-19 in PLOS ONE.

• The 2022 Asia-Pacific (APAC) Symposium will be held Nov. 12-13 at the Taipei Medical University in Taiwan. There will be both in-person and remote components to this event, which will include tutorials on Nov. 12 and the main conference on Nov. 13. More information and registration links are available here.

• The next edition of the Early-Stage Researcher workgroup Career Speaker Series will be held Monday, Nov. 14 from 11 am – 12 pm, and will feature a conversation with Rupa Makadia, Director, Observational Health Data Analytics, Johnson and Johnson. You can join this meeting here.

The latest edition of The Journey newsletter is now available, and includes all links from the OHDSI Symposium, as well as the monthly video podcast, October publications and presentations, community updates, and plenty more.

• Videos and slides from both the main day and the full-day tutorial at the 2022 OHDSI Symposium have now been posted.

• Do you represent a healthcare system that has adopted OMOP? The Healthcare Systems Interest Group is gathering evidence to support additional healthcare systems’ adoption decisions, and the workgroup wants to hear about the benefits your organization has realized. Please take this survey!

• Volume 2 of Our Journey: Where the OHDSI Community Has Been, And Where We Are Going was announced and presented at the OHDSI Symposium. A PDF of the updated book is now available on OHDSI.org. If you are interested in ordering a set of books for your own institution, please send an email to Manny Khemai (manny@abgprint.com), who represents the printing company.

OHDSI Social Showcase

• The #OHDSISocialShowcase begins this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: PHAROS, Platform for Harmonizing and Accessing Data in Real-time on Infectious Disease Surveillance Based on OMOP-CDM in Korea (Chungsoo Kim)

Tuesday: Understanding circe-be logic through Capr for generating complex cohort definitions (Martin Lavallee)

Wednesday: Characterization of first-line treatment for Breast Cancer and Multiple Myeloma using Electronic Health Record and Claims Databases (Maura Beaton)

Thursday: The Seasonality Score: A Quantitative Complement to Qualitative Seasonality Assessment (Anthony Molinaro)

Friday: Development of Lung Cancer Survival Prediction Models Based on Real-world Data and Machine Learning (Jason Hsu)

Openings

• Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (https://impactengines.northeastern.edu/ie/rwhn/). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

 • The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Community Updates | Zhang Slides | Zelko Slides

Videos

Analyzing the Effect of Hypertension on Retinal Thickness Using Radiology CDM (Chul Hyoung Park)

Assessing Racial Fairness of Dialysis Allocation in End-Stage Renal Disease (Linying Zhang)

A Pilot Characterization Study Assessing Health Equity in Mental Healthcare Delivery within the State of Georgia (Jacob Zelko)

The Nov. 1 community call focused on “Meeting the Titans.” The recipients of the 2022 Titan Awards discussed their journey to OHDSI, work they did over the past year, and more. The 2022 Titan Award honorees were:

Data Standards: Melanie Philofsky, Odysseus Date Services
Methodological Research: Fan Bu, UCLA 
Open-Source Development: Egill Fridgeirsson, Erasmus MC and James Gilbert, Janssen Research and Development
Clinical Applications: Xintong Li, University of Oxford
Community Collaboration: Ajit Londhe, Boehringer Ingelheim
Community Leadership: Paul Nagy, Johns Hopkins University
Community Support: Craig Sachson, Columbia University

Community Updates

• Congratulations to the team of Philipp Wegner, Geena Mariya Jose, Vanessa Lage-Rupprecht, Sepehr Golriz Khatami, Bide Zhang, Stephan Springstubbe, Marc Jacobs, Thomas Linden, Cindy Ku, Bruce Schultz, Martin Hofmann-Apitius, Alpha Tom Kodamullil for the COPERIMOplus Consortium on the publication of Common data model for COVID-19 datasets in BioInformatics.

• Congratulations to the team of Hao Liu, Simona Carini, Zhehuan Chen, Spencer Phillips Hey, Ida Sim, and Chunhua Weng on the publication of Ontology-based categorization of clinical studies by their conditions in the Journal of Biomedical Informatics.

• Videos and slides from both the main day and the full-day tutorial at the 2022 OHDSI Symposium have now been posted.

• The latest edition of The Journey, OHDSI’s official monthly newsletter, is now available. It includes all details from the symposium, other community updates, a video podcast, publications from October, and plenty more.

• Are you running a network study that you would like to announce, discuss or call for collaboration about? The Nov. 15 community call will focus on network studies, and there is room for presenters to lead this session. Please reach out to Craig Sachson (sachson@ohdsi.org) if you are interested.

• Do you represent a healthcare system that has adopted OMOP? The Healthcare Systems Interest Group is gathering evidence to support additional healthcare systems’ adoption decisions, and the workgroup wants to hear about the benefits your organization has realized. Please take this survey!

• Volume 2 of Our Journey: Where the OHDSI Community Has Been, And Where We Are Going was announced and presented at the OHDSI Symposium. A PDF of the updated book is now available on OHDSI.org. If you are interested in ordering a set of books for your own institution, please send an email to Manny Khemai (manny@abgprint.com), who represents the printing company.

• The 2022 Asia-Pacific (APAC) Symposium will be held Nov. 12-13 at the Taipei Medical University in Taiwan. There will be both in-person and remote components to this event, which will include tutorials on Nov. 12 and the main conference on Nov. 13. More information and registration links are available here.

OHDSI Social Showcase

• The #OHDSISocialShowcase continues this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Representing and Utilizing Clinical Textual Data for Real World Studies: An OHDSI Approach (Vipina Keloth)
Tuesday: Explaining patient-level prediction models using permutation feature importance and SHAP (Aniek Markus)
Wednesday: Jackalope: A software tool for meaningful post-coordination for ETL purposes (Eduard Korchmar)
Thursday: Clinical Sequelae of COVID-19 & Associated Healthcare Utilization: A Study Protocol (Ivan Chun Hang Lam)
Friday: Accurate Oncology Regimen Annotation and analysis of real-world oncology treatment patterns across five academic institutions (Travis Zack)

Openings

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Community Updates

Videos

Melanie Philofsky
Fan Bu
Egill Fridgeirsson
James Gilbert
Xintong Li
Ajit Londhe
Paul Nagy
Craig Sachson

George Hripcsak and Patrick Ryan led a session that included over 200 community members about what potential future directions the OHDSI community can consider. There were discussions around work in characterization, estimation and prediction, as well as how to strengthen a trio of OHDSI pillars: standardized vocabularies, standardized data network, and standardized open-source tools. This was just the start of an ongoing conversation, so be on the lookout for future community calls that address this topic.

After the call, community members were asked to suggest and vote on future directions that OHDSI should consider. Voting will remain open for a day or two following the call, so you can add you input here.

Community Updates

• Congratulations to the recipients of the Best Community Contribution Award from the 2022 Symposium. 

Data Standards: Analyzing the Effect of Hypertension on Retinal Thickness Using Radiology Common Data Model (R-CDM) (Chul Hyoung Park, Rae Woong Park, Sang Jun Park, Da Yun Lee, Seng Chan You, Ki Hwang Lee)
Methodological Research: Assessing Racial Fairness of Dialysis Allocation in End-Stage Renal Disease (Linying Zhang, Lauren R. Richter, David M. Blei, Yixin Wang, Anna Ostropolets, Noemie Elhadad, George Hripcsak)
Open-Source Analytics: Cohort Definition Validation in Atlas (Charity Hilton, Saul Crumpton, Jon Duke)
Clinical Applications: A Pilot Characterization Study Assessing Health Equity in Mental Healthcare Delivery within the State of Georgia (Jacob Zelko, Malina Hy, Varshini Chinta, Emily Liau, Morgan Knowlton, Jon Duke)

• Congratulations to the team of Elzo Pereira Pinto Junior, Priscilla Normando, Renzo Flores-Ortiz, Muhammad Usman Afzal, Muhammad Asaad Jamil, Sergio Fernandez Bertolin, Vinícius de Araújo Oliveira, Valentina Martufi, Fernanda de Sousa, Amir Bashir, Edward Burn, Maria Yury Ichihara, Maurício L Barreto, Talita Duarte Salles, Daniel Prieto-Alhambra, Haroon Hafeez, and Sara Khalid on the publication of Integrating real-world data from Brazil and Pakistan into the OMOP common data model and standardized health analytics framework to characterize COVID-19 in the Global South in JAMIA.

• Congratulations to the team of Antoine Lamer, Mathilde Fruchart, Nicolas Paris, Benjamin Popoff, Anaïs Payen, Thibaut Balcaen, William Gacquer, Guillaume Bouzillé, Marc Cuggia, Matthieu Doutreligne, and Emmanuel Chazard on the publication of Standardized Description of the Feature Extraction Process to Transform Raw Data Into Meaningful Information for Enhancing Data Reuse: Consensus Study in JMIR Medical Informatics.

• Are you running a network study that you would like to announce, discuss or call for collaboration about? The Nov. 15 community call will focus on network studies, and there is room for presenters to lead this session. Please reach out to Craig Sachson (sachson@ohdsi.org) if you are interested.

• Do you represent a healthcare system that has adopted OMOP? The Healthcare Systems Interest Group is gathering evidence to support additional healthcare systems’ adoption decisions, and the workgroup wants to hear about the benefits your organization has realized. Please take this survey!

• PIONEER is IMI’S “Big Data for Better Outcomes” program. The research objective of the upcoming  study-a-thon is to ‘Identify amongst patients with metastatic hormone-sensitive prostate cancer treated with one of the approved treatment plans, which will experience progression and death during an established follow-up period.’ The study-a-thon is scheduled for the week of Oct 31 in Leiden, Netherland with an option to join remotely. There will be three main workgroups focusing on phenotype development, analytical package development and study execution by data owners. We welcome anyone who is interested to contribute your data, join one of the workgroups or simply come and observe.

• Volume 2 of Our Journey: Where the OHDSI Community Has Been, And Where We Are Going was announced and presented at the OHDSI Symposium. A PDF of the updated book is now available on OHDSI.org. If you are interested in ordering a set of books for your own institution, please send an email to Manny Khemai (manny@abgprint.com), who represents the printing company.

• The 2022 Asia-Pacific (APAC) Symposium will be held Nov. 12-13 at the Taipei Medical University in Taiwan. There will be both in-person and remote components to this event, which will include tutorials on Nov. 12 and the main conference on Nov. 13. More information and registration links are available here.

OHDSI Social Showcase

• The #OHDSISocialShowcase begins this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: Comparing broad and narrow phenotype algorithms: differences in performance characteristics and immortal time incurred (Joel Swerdel)
Tuesday: Mapping variants of known significance to the OMOP Genomic Vocabulary (Michael Gurley)
Wednesday: Mortality prediction after PCI/CABG using ECG and comorbidities (Stijn Dupulthys)
Thursday: Introduction of a standardized framework to develop deep-learning models using the OMOP-CDM (Chungsoo Kim)
Friday: Phenotyping of a Large Primary Spinal Cord Tumor Cohort Identified through an Observational Healthcare Database (Hart P. Fogel)

Openings

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Future Directions of OHDSI | Community Updates

Video

Patrick Ryan and Craig Sachson provided an overview of the OHDSI community, and all of the resources available on the OHDSI website, during the Oct. 18 community call. The video is posted below. 

Community Updates

• Congratulations to the team of Woo Kyung Bae, Jihoon Cho, Seok Kim, Borham Kim, Hyunyoung Baek, Wongeun Song, and Sooyoung Yoo on the publication of Coronary Artery Computed Tomography Angiography for Preventing Cardio-Cerebrovascular Disease: Observational Cohort Study Using the Observational Health Data Sciences and Informatics’ Common Data Model in JMIR Medical Informatics.

• Congratulations to the team of Vaclav Papez, Maxim Moinat, Erica A Voss, Sofia Bazakou, Anne Van Winzum, Alessia Peviani, Stefan Payralbe, Michael Kallfelz, Folkert W Asselbergs, Daniel Prieto-Alhambra, Richard J B Dobson, and Spiros Denaxas on the publication of Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond in JAMIA.

• Congratulations to the team of Lara J Kanbar, Judith W Dexheimer, Janet Zahner, Evanette K Burrows, Robert Chatburn, Amanda Messinger, Christopher D Baker, Christine L Schuler, Dan Benscoter, Raouf Amin, and Nathan Pajor on the publication of Standardizing Electronic Health Record Ventilation Data in the Pediatric Long-Term Mechanical Ventilator Dependent Population in Pediatric Pulmonology.

• Congratulations to the team of Najia Ahmadi, Yuan Peng, Markus Wolfien, Michéle Zoch, and Martin Sedlmayr on the publication of OMOP CDM Can Facilitate Data-Driven Studies for Cancer Prediction: A Systematic Review in the International Journal of Molecular Studies.

• Thank you to everybody who came out for the OHDSI 2022 Symposium this past weekend. All materials (videos, slides, Collaborator Showcase research) will be posted when available. Please check out our symposium homepage to find everything when it is posted.

• The 2022 Titan Award winners were announced during the closing of the 2022 OHDSI Symposium. Congratulations to all of our winners, and to the 50+ individuals or groups who were nominated! Visit our Titan Awards homepage to learn more about the awards and to see all past recipients.

Data Standards: Melanie Philofsky, Odysseus Date Services
Methodological Research: Fan Bu, UCLA
Open-Source Development: Egill Fridgeirsson, Erasmus MC and James Gilbert, Janssen Research and Development
Clinical Applications: Xintong Li, University of Oxford
Community Collaboration: Ajit Londhe, Boehringer Ingelheim
Community Leadership: Paul Nagy, Johns Hopkins University
Community Support: Craig Sachson, Columbia University

• Volume 2 of Our Journey: Where the OHDSI Community Has Been, And Where We Are Going was announced and presented at the OHDSI Symposium. A PDF of the updated book is now available on OHDSI.org.

• EHDEN is hosting its seventh and final open call for European data partners who are interested in mapping their patient data to OMOP. Through six open calls, EHDEN was welcoming 166 data partners across 26 countries to its federated network, and this is the final opportunity to join this effort. The deadline to apply is Friday, Nov. 11.

• The 2022 Asia-Pacific (APAC) Symposium will be held Nov. 12-13 at the Taipei Medical University in Taiwan. There will be both in-person and remote components to this event, which will include tutorials on Nov. 12 and the main conference on Nov. 13. More information and registration links are available here.

Openings

• FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

Slides

Community Updates

Video

Members of the 2022 Collaborator Showcase had 60 seconds to explain why people should visit their poster or software demo at the 2022 OHDSI Symposium. Check out the video at the bottom of this session. 

If you have not registered for the main conference or any of the other weekend events, or you want to learn more about #OHDSI2022, please visit our Symposium Homepage.

Community Updates

• Congratulations to the team of Stephen Fortin, Jenna Reps, and Patrick Ryan on the publication of Adaptation and validation of a coding algorithm for the Charlson Comorbidity Index in administrative claims data using the SNOMED CT standardized vocabulary in BMC Medical Informatics and Decision Making.

• The updated version of the 2022 Symposium agenda is now available, and it includes all the posters and software demos that will be included in the collaborator showcase. If you haven’t registered yet, you can still do on our OHDSI2022 homepage.

• EHDEN is hosting its seventh and final open call for European data partners who are interested in mapping their patient data to OMOP. Through six open calls, EHDEN was welcoming 166 data partners across 26 countries to its federated network, and this is the final opportunity to join this effort. The deadline to apply is Friday, Nov. 11.

• The 2022 Asia-Pacific (APAC) Symposium will be held Nov. 12-13 at the Taipei Medical University in Taiwan. There will be both in-person and remote components to this event, which will include tutorials on Nov. 12 and the main conference on Nov. 13. More information and registration links are available here.

Openings

• The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

Mad Minutes

The Oct. 4 community call featured another session of OHDSI Debates. Four members of the OHDSI community joined to take part in two debates, and the community judged the winners!

Debate 1: Where should we focus OHDSI’s open-source development activities: Web-based front-ends to enable broader adoption vs. R package back-end development for advanced large-scale analytics

Debaters: Adam Black (Data Scientist, Odysseus Data Services, Inc.) vs. James Gilbert (Manager in Epidemiology Analytics, Janssen Research & Development)

Debate 2: Strategy for OHDSI network studies: Get as many databases as possible vs. Get enough to answer the question quickly

Debaters: Erica Voss (Senior Director, Janssen Research & Development) vs. Ed Burn (Senior Researcher in Epidemiology and Health Economics, University of Oxford)

If you have not registered for the main conference or any of the other weekend events, or you want to learn more about #OHDSI2022, please visit our Symposium Homepage.

Community Updates

• Congratulations to the team of Yerim Kim, Seung In Seo, Kyung Joo Lee, Jinseob Kim, Jong Jin Yoo, Won-Woo Seo, and Woon Geon Shin on the publication of Risks of Long-term use of Proton Pump Inhibitor on Ischemic Vascular Events: A distributed network analysis of 5 real-world observational Korean databases using a Common Data Model in International Journal of Stroke.

• Congratulations to the team of Akihiko Nishimura, Junqing Xie, Kristin Kostka, Talita Duarte-Salles, Sergio Fernández Bertolín, María Aragón, Clair Blacketer, Azza Shoaibi, Scott DuVall, Kristine Lynch, Michael Matheny, Thomas Falconer, Daniel Morales, Mitchell Conover, Seng Chan You, Nicole Pratt, James Weaver, Anthony Sena, Martijn Schuemie, Jenna Reps, Christian Reich, Peter Rijnbeek, Patrick Ryan, George Hripcsak, Daniel Prieto-Alhambra, and Marc Suchard on the publication of International cohort study indicates no association between alpha-1 blockers and susceptibility to COVID-19 in benign prostatic hyperplasia patients in Frontiers of Pharmacology.

• The updates version of the 2022 Symposium agenda is now available, and it includes all the posters and software demos that will be included in the collaborator showcase. If you haven’t registered yet, you can still do on our OHDSI2022 homepage.

• There will be a “Meet The Mentors” session at the OHDSI Symposium. The purpose of this event is to give members an opportunity to network with OHDSI ‘veterans’ through a speed-dating activity. If you’re interested in having a 10 minute in-person conversation with a leading OHDSI researcher and veteran, please fill out this form, and the organizers will work to set you up with one of your top choices. You are welcome to chat with Mentors on any topics, including professional experience, career advice, finding a job in a field that interests you, and more.

• Do you want to promote your OHDSI poster or software demo during the”Mad Minutes” Oct. 11 community call, the final one before the symposium? Sign up now, and we will give as many collaborators as possible 60 seconds to tell the community why they should visit you during the Collaborator Showcase.

• The latest edition of The Journey Newsletter is now available. It includes information on the symposium, the Clinical Registries and HTA Challenge sessions, a collaborator spotlight on Jing Li, publications from September, and plenty more. If you don’t receive our monthly newsletter, you can sign up here.

• The new India Regional Chapter was announced recently. Learn more about the chapter, its goals, and how to collaborate with this chapter in this flyer. 

• The 2022 Asia-Pacific (APAC) Symposium will be held Nov. 12-13 at the Taipei Medical University in Taiwan. There will be both in-person and remote components to this event, which will include tutorials on Nov. 12 and the main conference on Nov. 13. More information and registration links are available here.

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

Debate: Where should we focus OHDSI’s open-source development activities: Web-based front-ends to enable broader adoption vs. R package back-end development for advanced large-scale analytics (Adam Black vs. James Gilbert)

Debate: Strategy for OHDSI network studies: Get as many databases as possible vs. Get enough to answer the question quickly (Erica Voss vs. Ed Burn)

During the Sept. 27 ‘HTA Challenge’ community call, international leaders in health technology assessment led a session to figure out ways that the OHDSI community can enhance the tools and standards for HTA around the world. This session was led by Dalia Dawoud and Jamie Elvidge of the National Institute for Health and Care Excellence, and Marie Osterberg and Lena Wallgren from the Swedish Agency for Health Technology Assessment and Assessment of Social Services.

If you have not registered for the main conference or any of the other weekend events, or you want to learn more about #OHDSI2022, please visit our Symposium Homepage.

Community Updates

• Congratulations to the team of Rory J. McCrimmon, Alice Y.Y. Cheng, Gagik Galstyan, Khier Djaballah, Xuan Li, Mathieu Coudert, and Juan P. Frias on the publication of iGlarLixi versus basal plus Rapid-Acting insulin in adults with type 2 diabetes advancing from basal insulin therapy: The SoliSimplify Real-World study in Diabetes, Obesity and Metabolism.

• Congratulations to George Hripcsak, chair of the OHDSI Coordinating Center at Columbia University, on being announced as the 2022 recipient of the Morris F. Collen Award of Excellence, the top honor in the field of informatics. He will receive this honor at the 2022 AMIA Symposium.

• The latest OHDSI Collaborator Spotlight features Jing Li, an Associate Director of Data Science at IQVIA. In this edition, Jing discusses her career and how she moved into healthcare, her excitement about the growing APAC community, and plenty more.

• The full agenda for the OHDSI 2022 Symposium is now available. Check out the main conference schedule, which includes a plenary on objective diagnostics, presentations around OHDSI support for regulatory authorities, the collaborator showcase and plenty more.

• The new India Regional Chapter was announced last week. Learn more about the chapter, its goals, and how to collaborate with this chapter in this flyer.

• Jon Duke recently announced an opening for a Branch Head – Health Interoperability and Security-ICL in the Georgia Tech Research Institute (GTRI). The application deadline is Nov. 13, 2022. More information and an application link is available here.

• Tim Burdick posted an opening for a Senior Database Developer at Dartmouth Health (DH). This position would be the lead developer for DH research database management systems, including OMOP, as well as i2b2, TriNetX, tiCrypt, and research use of REDCap. More information on this remote position, as well as an application link, is available here.

• Talita Duarte-Salles, a 2020 OHDSI Titan Award honoree, recently announced an opening for a post-doc to join her Real World Epidemiology group at the The Institut d’Investigació en Atenció Primària Jordi Gol (IDIAPJGol); more information is available here.

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

HTA Challenge: NICE | HTA Challenge: SBU | Community Updates

Video Presentation

HTA Challenge

The Sept. 20 community call focused on the 2022 Symposium. Patrick Ryan went through the full weekend, including the main conference and the full-day tutorial, to highlight all of the activities that will be happening Oct. 14-16.

If you have not registered for the main conference or any of the other weekend events, or you want to learn more about #OHDSI2022, please visit our Symposium Homepage.

Community Updates

• Congratulations to the team of Linying Zhang, Yixin Wang, Martijn Schuemie, David Blei, and George Hripcsak on the publication of Adjusting for indirectly measured confounding using large-scale propensity score in the Journal of Biomedical Informatics.

• Congratulations to the team of Victor G. Castano, Matthew Spotnitz, Genna J. Waldman, Evan F. Joiner, Hyunmi Choi, Anna Ostropolets, Karthik Natarajan, Guy M. McKhann, Ruth Ottman, Alfred I. Neugut, George Hripcsak, and Brett E. Youngerman on the publication of Identification of patients with drug resistant epilepsy in electronic medical record data using the Observational Medical Outcomes Partnership Common Data Model in Epilepsia.

• The agenda for #OHDSI2022 is now available. It includes a full schedule for the main conference on Oct. 14, as well as a listing of the software demos planned for the collaborator showcase (posters will be shared in a later version). The agenda also includes details about the full-day tutorial on Saturday and the workgroup activities planned throughout the weekend.

• The new India Regional Chapter was announced this week. Learn more about the chapter, its goals, and some of its leaders, in this flyer.

• Jon Duke recently announced an opening for a Branch Head – Health Interoperability and Security-ICL in the Georgia Tech Research Institute (GTRI). The application deadline is Nov. 13, 2022. More information and an application link is available here.

• Talita Duarte-Salles, a 2020 OHDSI Titan Award honoree, recently announced an opening for a post-doc to join her Real World Epidemiology group at the The Institut d’Investigació en Atenció Primària Jordi Gol (IDIAPJGol); more information is available here.

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Current Status of OMOP-CDM in Asia-Pacific regions and Lessons for Data Quality Assessment: Collaborative CDM Inspection Study (Chungsoo Kim)
Tuesday – Pregnancy extension table in the OMOP CDM (Alicia Abellan)
Wednesday – The EHDEN Portal – an entry web platform for OMOP CDM resources (José Oliveira)

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentations

OHDSI2022 Symposium Preview

.

The Sept. 13 community call was focused on Clinical Registry Efforts in OHDSI. We heard four presentations during this session:

• How clinical registries and OHDSI can benefit from each other (Paul Nagy • Program Director for Graduate Training in Biomedical Informatics and Data Science, Deputy Director of the Johns Hopkins Medicine Technology Innovation Center)
• How to adapt a manual clinical registry to OMOP (Matt Robinson • Assistant Professor, The Johns Hopkins University School of Medicine)
• How to lower the ETL barrier going to OMOP with Perseus (Demonstration) (Zachary Wang • Graduate Student, Johns Hopkins and 2022 Kheiron Cohort member)
• Lowering the deployment burden with the cloud (Lee Evans • Owner, LTS Computing LLC)

The following presentation was planned, but it will be rescheduled due to time constraints.

• Distributed Machine Learning Using OMOP (Emily Pfaff • Research Assistant Professor, University of North Carolina at Chapel Hill)

Videos and slides from these presentations are available at the bottom of this section.

Community Updates

• Congratulations to the team of Joao Rafael Almeida, Joao Paulo Barraca, and José Luís Oliveira on the publication of Preserving Privacy when Querying OMOP CDM Databases in Volume 298 of Studies in Health Technology and Informatics.

• Congratulations to the team of Guohui Xiao, Emily Pfaff, Eric Prud’hommeaux, David Booth, Deepak K Sharma, Nan Huo, Yue Yu, Nansu Zong, Kathryn J Ruddy, Christopher Chute, and Guoqian Jiang on the publication of FHIR-Ontop-OMOP: Building Clinical Knowledge Graphs in FHIR RDF with the OMOP Common Data Model in the Journal of Biomedical Informatics.

• Congratulations to the team of Benoit L Marteau, Yuanda Zhu, Felipe Giuste, Wenqi Shi, Ashley Carpenter, Coleman Hilton, and May D Wang on the publication of Accelerating Multi-site Health Informatics with Streamlined Data Infrastructure using OMOP-on-FHIR in the Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

• Congratulations to the 53 individuals or teams who were nominated for a 2022 Titan Award. The Titan Award recipients will be announced during the closing talk at the 2022 OHDSI Symposium. The 2022 recipients are:

Thamir Alshammary • Juan Banda • Adam Black • Fan Bu • Montse Camprubi • Yong Chen • Marcel de Wilde • Frank DeFalco • Egill Fridgeirsson • Jamie Gilbert • Jake Gillberg • Jason Hsu • Nigel Hughes • Yu-Chuan Jack Li • Mik Kallfelz • Andy Kanter • Elisse Katzman • Chungsoo Kim • Greg Klebanov • Chris Knoll • Kristin Kostka • Manlik Kwong • Christophe Lambert • Martin Lavallee • Jing Li • Xintong Li • Star Liu • Ajit Londhe • Aniek Markus • Evan Minty • Paul Nagy • Karthik Natarajan • Aki Nishimura • Anna Ostropolets • Melanie Philofsky • Gowtham Rao • Berta Raventos • Craig Sachson • Martijn Schuemie • Azza Shoaibi • Marc Suchard • Cynthia Sung • Joel Swerdel • May Terry • Don Torok • Cynthia Yang • Jacob Zelko • Center for Surgical Science Prediction study team • LEGEND-T2DM • N3C • Thrombosis w Thrombocytopenia phenotype project team • Vaccine Evidence Workgroup

• The agenda for #OHDSI2022 is now available. It includes a full schedule for the main conference on Oct. 14, as well as a listing of the software demos planned for the collaborator showcase (posters will be shared in a later version). The agenda also includes details about the full-day tutorial on Saturday and the workgroup activities planned throughout the weekend.

• The latest edition of The Journey newsletter is now available. This newsletter includes community updates, links to 13 August publications, the symposium agenda, a video update podcast, and plenty more. If you don’t subscribe to the newsletter, you can do so here.

• Talita Duarte-Salles, a 2020 OHDSI Titan Award honoree, recently announced an opening for a post-doc to join her Real World Epidemiology group at the The Institut d’Investigació en Atenció Primària Jordi Gol (IDIAPJGol); more information is available here.

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Common data environment for source vocabularies mapping (Irina Zherko)
Tuesday – From ATLAS to predictive modeling CDM data extracting & Study preparations (Guy Livne)
Wednesday – Utilising real-world evidence for health technology assessment: development of a cancer survival use case (Ravinder Claire)
Thursday – Applying k-anonymity and l-diversity in OMOP CDM databases (João Almeida)
Friday – Trial feasibility assessments in federated hospital EHR networks, based on OMOP CDM: An objective of the IMI EU-PEARL Consortium (Eva-Maria Didden)

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Clinical Registry Presentation | Community Updates

Video Presentations

Clinical Registry Efforts Within OHDSI

During the Sept. 6 community call, we learned about five published studies that have come from our community over the last few months:

• A database of pediatric drug effects to evaluate ontogenic mechanisms from child growth and development (Nick Giangreco)
• Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis (Cynthia Yang)
• Empirical assessment of alternative methods for identifying seasonality in observational healthcare data (Anthony Molinaro)
• Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thrombocytopenia in Real World Data: A Multinational Network Cohort Study (Azza Shoaibi)
• TreatmentPatterns: An R package to facilitate the standardized development and analysis of treatment patterns across disease domains (Aniek Markus)

Videos and slides from these presentations are available at the bottom of this section.

Community Updates

• Congratulations to the 53 individuals or teams who were nominated for a 2022 Titan Award. The Titan Award recipients will be announced during the closing talk at the 2022 OHDSI Symposium. The 2022 recipients are:

Thamir Alshammary • Juan Banda • Adam Black • Fan Bu • Montse Camprubi • Yong Chen • Marcel de Wilde • Frank DeFalco • Egill Fridgeirsson • Jamie Gilbert • Jake Gillberg • Jason Hsu • Nigel Hughes • Yu-Chuan Jack Li • Mik Kallfelz • Andy Kanter • Elisse Katzman • Chungsoo Kim • Greg Klebanov • Chris Knoll • Kristin Kostka • Manlik Kwong • Christophe Lambert • Martin Lavallee • Jing Li • Xintong Li • Star Liu • Ajit Londhe • Aniek Markus • Evan Minty • Paul Nagy • Karthik Natarajan • Aki Nishimura • Anna Ostropolets • Melanie Philofsky • Gowtham Rao • Berta Raventos • Craig Sachson • Martijn Schuemie • Azza Shoaibi • Marc Suchard • Cynthia Sung • Joel Swerdel • May Terry • Don Torok • Cynthia Yang • Jacob Zelko • Center for Surgical Science Prediction study team • LEGEND-T2DM • N3C • Thrombosis w Thrombocytopenia phenotype project team • Vaccine Evidence Workgroup

• The agenda for #OHDSI2022 is now available. It includes a full schedule for the main conference on Oct. 14, as well as a listing of the software demos planned for the collaborator showcase (posters will be shared in a later version). The agenda also includes details about the full-day tutorial on Saturday and the workgroup activities planned throughout the weekend.

• Please take our 2022 data survey so that we can update our data network information before the 2022 symposium. This survey (see image) should take less than 2 minutes; it asks for the name of the data partner, country, type of data, number of patients, and a contact person. The deadline for the survey is Sept. 9, but please do this at your earliest convenience.

• The latest edition of The Journey newsletter is now available. This newsletter includes community updates, links to 13 August publications, the symposium agenda, a video update podcast, and plenty more. If you don’t subscribe to the newsletter, you can do so here.

• The next edition of the CBER Best Seminar will be held Wednesday, Sept. 7, at 11 am, with a presentation from Dr. Matthew Fox of Boston University on Quantitative Bias Analysis Methods to Improve Inferences. You can register for this session here.

• The next edition of the Early-Stage Researcher Speaker Series will be held Monday, Sept. 12 (11 am – 12 pm ET), when Jenna Reps discusses her career path, her work with the PatientLevelPrediction workgroup and more. You can join the meeting here.

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – External validation of existing dementia prediction models on observational data (Henrik John)
Tuesday – Characteristics and outcomes of inflammatory bowel disease patients: an open, multinational OHDSI network study (Chen Yanover)
Wednesday – Mapping PROMs data from the Dutch PROFILES registry to the OMOP CDM – experiences and challenges (Peter Prinsen)
Thursday – OHDSI Germany: A recap after one year (Michele Zoch)
Friday – A dashboard for visual comparison of OMOP CDM databases (João Almeida, José Oliveira)

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Giangreco | Yang | Molinaro | Shoaibi | Markus | Community Updates

Video Presentations

A database of pediatric drug effects to evaluate ontogenic mechanisms from child growth and development (Nick Giangreco)

Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis (Cynthia Yang)

Empirical assessment of alternative methods for identifying seasonality in observational healthcare data (Anthony Molinaro)

Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thrombocytopenia in Real World Data: A Multinational Network Cohort Study (Azza Shaoibi)

TreatmentPatterns: An R package to facilitate the standardized development and analysis of treatment patterns across disease domains (Aniek Markus)

https://youtu.be/lu4fcOXdlJs

During the Aug. 30 community call, we heard about two exciting initiatives coming from our colleagues at the European Health Data & Evidence Network (EHDEN), the EHDEN Portal and the EHDEN Academy. We were excited to have the following community leaders lead this session:

• Julia Kurps (Team Lead, Real World Data • The Hyve)
• Nigel Hughes (Scientific Director, Observational Health Data Analytics/Epidemiology • Janssen Research and Development)

Videos and slides from these presentations are available at the bottom of this section.

Community Updates

• Congratulations to the team of Rashmie Abeysinghe, Adam Black, Denys Kaduk, Yupeng Li, Christian Reich, Alexander Davydov, Lixia Yao, and Licong Cui on the publication of Towards quality improvement of vaccine concept mappings in the OMOP vocabulary with a semi-automated method in the Journal of Biomedical Informatics.

• Congratulations to Dani Prieto-Alhambra on receiving a Special ISPE Award for Contributions to Public Health Associated with the COVID-19 Pandemic during ICPE2022.

• The agenda for #OHDSI2022 is now available. It includes a full schedule for the main conference on Oct. 14, as well as a listing of the software demos planned for the collaborator showcase (posters will be shared in a later version). The agenda also includes details about the full-day tutorial on Saturday and the workgroup activities planned throughout the weekend.

• Please take our 2022 data survey so that we can update our data network information before the 2022 symposium. This survey (see image) should take less than 2 minutes; it asks for the name of the data partner, country, type of data, number of patients, and a contact person. The deadline for the survey is Sept. 9, but please do this at your earliest convenience.

• Nominations are open for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Characterization of Health by OHDSI Asia-Pacific chapter to identify Temporal Effect of the Pandemic for Cardiovascular Diseases (CHAPTER-CVDs) (Seng Chan You)
Tuesday – The Finnish OMOP data network (FinOMOP) (Javier Gracia-Tabuenca)
Wednesday – Impact of the COVID-19 pandemic on eating disorders among adolescents and young adults in Catalonia: a population-based cohort study (Berta Raventós)
Thursday – Challenges and possible solutions for the maintenance of the OMOP CDM Standardized Vocabularies (Eduard Korchmar
Friday – An EHDEN Data Partner Experience: Transforming the Hospital i2b2 data repository into OMOP common data model (M Teresa Garcia Morales)

2022 OHDSI Symposium

• Registration is for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Agenda | FAQs

Oct. 14 – Main Conference: Information | Registration | Agenda | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

EHDEN Portal | Community Updates

Video Presentations

EHDEN Portal (Julia Kurps)

EHDEN Academy (Nigel Hughes)

The Aug. 23 OHDSI community call featured the latest session of workgroup updates. We received annual updates from the following workgroup leads. 

• Registry – Tina Parciak (PhD Student • UHasselt/BIOMED)
• Latin America — Jose Posada (Assistant Professor • Universidad del Norte)
• Health Equity – Jake Gillberg (Software Developer • Tufts Clinical and Translational Science Institute)
• Geographic Information System (GIS) – Robert Miller (Software Development Analyst • Tufts Clinical and Translational Science Institute)

Videos and slides from these presentations are available at the bottom of this section.

Community Updates

• Congratulations to the team of Shailja C. Shah, Andrew Canakis, Alese E. Halvorson, Chad Dorn, Otis Wilson, Jason Denton, in memoriam, Richard Hauger, Christine Hunt, Ayako Suzuki, Michael E. Matheny, Edward Siew, Adriana Hung, Robert A. Greevy, Jr., Christianne L. Roumie on the publication of Associations Between Gastrointestinal Symptoms and COVID-19 Severity Outcomes, Based on a Propensity Score-Weighted Analysis of a Nationwide Cohort in Gastro Hep Advances.

• Congratulations to the team of Joel Swerdel, Martijn Schuemie, Gayle Murray and Patrick Ryan on the publication of PheValuator 2.0: Methodological improvements for the PheValuator approach to semi-automated phenotype algorithm evaluation in the Journal of Biomedical Informatics.

• Please take our 2022 data survey so that we can update our data network information before the 2022 symposium. This survey (see image) should take less than 2 minutes; it asks for the name of the data partner, country, type of data, number of patients, and a contact person. The deadline for the survey is Sept. 9, but please do this at your earliest convenience.

• The latest edition of the Collaborator Spotlight features Paul Nagy, an assistant professor at Johns Hopkins and a leader in the OHDSI community, especially within our developer network. He shares thoughts on the new open-source community, how Johns Hopkins is joining the journey, and what hobby has him ‘covered’ moments before many OHDSI calls!

• All prior collaborator spotlights are now available here.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – The european health data &evidence network (ehden)–sharing the ohdsi journey and a vision of evidence today, not in several tomorrows (Nigel Hughes)
Tuesday – Mapping UK Biobank to the OMOP CDM: development of USAGI
(Maxim Moinat)
Wednesday – OMOP CDM for European rare disease registries (Rowdy de Groot)
Thursday – Impact of random oversampling and random undersampling on the development and validation of prediction models using observational health data (Cynthia Yang)
Friday – RCTrep: A package for the validation of methods for treatment effect estimation using real world data (Lingjie Shen)

Job Openings

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Registry WG | Latin America WG | Health Equity WG | Geographic Information System (GIS) WG |  Community Updates

Video Presentations

Registry WG (Tina Parciak)

Latin America WG (Jose Posada)

Health Equity WG (Jake Gillberg)

GIS WG (Robert Miller)

The Aug. 16 OHDSI community call featured a session entitled “Speed Dating,” which saw the full attendance get broken into small groups of 4-6 people over four sessions to introduce themselves, meet new members of the community and share thoughts on some fun questions presented to them. The introductions were held in breakout rooms, so there isn’t video of those, but the community updates video is posted below.

Community Updates

• Congratulations to the team of Antoine Lamer, Mouhamed Djahoum Moussa, Romaric Marcilly, Régis Logier, Benoit Vallet and Benoît Tavernier on the publication of Development and usage of an anesthesia data warehouse: lessons learnt from a 10-year project in the Journal of Clinical Monitoring and Computing.

• Congratulations to the team of Aurore Nishimwe, Charles Ruranga, Clarisse Musanabaganwa, Regine Mugeni, Muhammed Semakula, Joseph Nzabanita, Ignace Kabano, Annie Uwimana, Jean N. Utumatwishima, Jean Damascene Kabakambira, Annette Uwineza, Lars Halvorsen, Freija Descamps, Jared Houghtaling, Benjamin Burke, Odile Bahati, Clement Bizimana, Stefan Jansen, Celestin Twizere, Kizito Nkurikiyeyezu, Francine Birungi, Sabin Nsanzimana and Marc Twagirumukiza on the publication of Leveraging artificial intelligence and data science techniques in harmonizing, sharing, accessing and analyzing SARS-COV-2/COVID-19 data in Rwanda (LAISDAR Project): study design and rationale in BMC Medical Informatics and Decision Making.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Conversion of Estonian health data into the OMOP CDM: insurance claims, prescription data and electronic health records (Marek Oja)
Tuesday – Developing a frailty concept in the OMOP CDM among sexual minority older adults (age 50+) in the All of Us database (Brianne Olivieri Mui)
Wednesday – CohortsExport: A Shiny app to explore and export data from the OMOP Common Data Model (Vittoria Ramella)
Thursday – Analyzing the impact of COVID-19 on the healthcare system: an OMOP-CDM framework applied to Northern Italy (Sara Conti)
Friday – Mapping UKB to the OMOP CDM: Challenges and Solutions (Sofia Bazakou)

Job Openings

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

Community Updates

During the Aug. 9 OHDSI Community Call, leads of the six Asia-Pacific (APAC) regional chapters provided mid-year updates. Thanks to all of our presenters on this call, who shared the exciting work, activities, ongoing studies and more:

• Jason Hsu (Taiwan)
• Mengling Feng (Singapore)
• Nicole Pratt (Australia)
• Tatsuo Hiramatsu (Japan)
• Seng Chan You (Korea)
• Lei Liu (China)

Community Updates

• Congratulations to the team of Maryam Khodaverdi, Bradley Price, Zachary Porterfield, Timothy Bunnell, Michael Vest, Alfred Jerrod Anzalone, Jeremy Harper, Wes Kimble, Hamidreza Moradi, Brian Hendricks, Susan Santangelo, Sally Hodder, and the N3C Consortium Collaborators on the publication of An ordinal severity scale for COVID-19 retrospective studies using Electronic Health Record data in JAMIA Open.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The latest edition of the OHDSI newsletter is now available, and it includes details about the CDM Update Process presentation, publications from July, community updates, presentations and more. If you don’t subscribe to the newsletter, you can do so here.

• The most recent Asia-Pacific (APAC) community call focused on two of the ongoing APAC network studies: Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19, and Real world safety of treatments for multiple sclerosis. Recording from that and all previous meetings, as well as the schedule and link for future meetings, are available on our APAC Community page.

• The OHDSI Social Showcase continues. Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Two Hurdles in delivery of productised analytics (Jack Brewster) 
Tuesday – Macrolides use among patients with asthma and chronic obstructive pulmonary disease – A drug utilization and prediction study (Victor Pera)
Wednesday – Challenges and solutions in using OMOP CDM to FAIRify a Dutch ICU quality registry (Daniel Puttmann)
Thursday – Defining the valid analytic space for quantitative bias analysis in pharmacoepidemiology (Jamie Weaver)
Friday – Transforming Danish Registries to the OMOP Common Data Model: use case on the Danish Colorectal Cancer Group (DCCG) Database (Adamantia Tsouchnika)

Job Openings

• Peter Rijnbeek and his team at Erasmus University is hiring a Secretary for the Darwin EU Coordination Center and Department of Medical Informatics. This position will be responsible for the day-to-day administrative tasks as the personal assistant for Peter Rijnbeek, and will also work as senior secretary for the Department of Medical Informatics, where you will support the staff together with a very experienced colleague. You will play a key role in enabling the research and education delivered by the department. Your work will include the usual responsibilities of a senior secretary such as managing agendas, handing the communication lines, managing changes in personnel, organizing (international meetings and conferences), etc. More information and an application link are available here, and the deadline is Aug. 14, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Building Organizational Support | PORPOISE Study | Community Updates

Video Presentation

Asia-Pacific Regional Updates

The focus of the Aug. 2 OHDS community call was a panel discussion on what it takes to build organizational support for adopting the OMOP CDM and OHDSI tools, as well as building organizational capacity for conducting observational research. Our panelists for this session included: 

• Greg Klebanov (CTO/SVP • Odysseus Data Services, Inc.)
• Ajit Londhe (Senior Manager, Center for Observational Research • AMGEN)
• Keran Moll (Director, HEOR Real World Data & Analytics Research • Regeneron)
• Paul Nagy (Program Director for Graduate Training in Biomedical Informatics and Data Science • Johns Hopkins University)

Video of this call was posted below. Also, Behzad Naderalvojoud presented a new network study coming out of Stanford University: Development and External Validation of ML Models for Identifying Patients at Risk of Postoperative Prolonged Opioid Use (PORPOISE)A Network Study on OMOP Databases.

Videos of both are available at the bottom of this section.

Community Updates

• Congratulations to the team of Karoline Bräuner, Andreas W. Rosen, Adamantia Tsouchnika, Julie S. Walbech, Mikail Gögenur, Viviane A. Lin, Johan Clausen, and Ismail Gögenur on the publication of Developing prediction models for short-term mortality after surgery for colorectal cancer using a Danish national quality assurance database in the International Journal of Colorectal Disease.

• Congratulations to the team of Carina Nina Vorisek, Moritz Lehne, Sophie Anne Ines Klopfenstein, Paula Josephine Mayer, Alexander Bartschke, Thomas Haese, and Sylvia Thun on the publication of Fast Healthcare Interoperability Resources (FHIR) for Interoperability in Health Research: Systematic Review in JMIR Medical Informatics.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The latest edition of the OHDSI newsletter is now available, and it includes details about the CDM Update Process presentation, publications from July, community updates, presentations and more. If you don’t subscribe to the newsletter, you can do so here.

• The most recent Asia-Pacific (APAC) community call focused on two of the ongoing APAC network studies: Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19, and Real world safety of treatments for multiple sclerosis. Recording from that and all previous meetings, as well as the schedule and link for future meetings, are available on our APAC Community page.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Comparing Data Quality Dashboard results from consecutive ETL iterations: two new visualizations and one utility script (Anne van Winzum)
Tuesday – OHDSI-On-A-Pi: Containerization of OHDSI Software Tools for Use on a Raspberry Pi (Jared Houghtaling)
Wednesday – Integration prospects of the Ukrainian healthcare system with OMOP CDM (Mariia Kolesnyk)
Thursday – Patient treatment trajectory modeling with Markov chains (Markus Haug)
Friday – Assessing treatment effect heterogeneity using the RiskStratifiedEstimation R-package (Alexandros Rekkas)

Job Openings

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Peter Rijnbeek and his team at Erasmus University is hiring a Secretary for the Darwin EU Coordination Center and Department of Medical Informatics. This position will be responsible for the day-to-day administrative tasks as the personal assistant for Peter Rijnbeek, and will also work as senior secretary for the Department of Medical Informatics, where you will support the staff together with a very experienced colleague. You will play a key role in enabling the research and education delivered by the department. Your work will include the usual responsibilities of a senior secretary such as managing agendas, handing the communication lines, managing changes in personnel, organizing (international meetings and conferences), etc. More information and an application link are available here, and the deadline is Aug. 14, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Building Organizational Support | PORPOISE Study | Community Updates

Video Presentation

Building Organizational Support Panel (Paul Nagy, Keran Moll, Greg Klebanov, Ajit Londhe)

PORPOISE Study Introduction and Call for Collaboration (Behzad Naderalvojoud)

The July 26 community call featured a session led by Clair Blacketer, Paul Nagy and Davera Gabriel on what to do when your data does not fit into the OMOP CDM. Our community continues to expand globally, and both individuals and organizations often look for new enhancements to the CDM. There will be a new decision tree and process implemented to try and streamline this procedure and to clarify how data model requests are made and codified, and these were presented and discussed during this meeting. Video of this call is posted below.

Community Updates

• Congratulations to the team of Martijn Schuemie, Faaizah Arshad, Nicole Pratt, Fredrik Nyberg, Thamir Alshammari, George Hripcsak, Patrick Ryan, Daniel Prieto-Alhambra, Lana Lai, Xintong Li, Stephen Fortin, Evan Minty and Marc Suchard on the publication of Vaccine Safety Surveillance Using Routinely Collected Healthcare Data—An Empirical Evaluation of Epidemiological Designs in Frontiers in Pharmacology.

• Congratulations to the team of Jimmy Phuong, Stephanie Hong, Matvey B. Palchuk, Juan Espinoza, Daniella Meeker, David A. Dorr, Galina Lozinski, Charisse Madlock-Brown, and William G. Adams on the publication of Advancing Interoperability of Patient-level Social Determinants of Health Data to Support COVID-19 Research in the AMIA Annual Symposium Proceedings Archive.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The next Asia-Pacific (APAC) community call takes place Thursday, July 28 (July 27 in the Western Hemisphere) and will focus on two of the ongoing APAC network studies: Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19, and Real world safety of treatments for multiple sclerosis. Links to the meeting and previous recordings are available on our APAC Community homepage.

• Videos from all presentations during the main day of the OHDSI European Symposium are now available.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Mapping of complex constructs in OMOP CDM (Alexander Davydov)
Tuesday – Implementing the OHDSI Community Approach to Phenotype a Complex Medical Condition in European Primary Care Data (Kristin Kostka)
Wednesday – The use of data-driven vs. clinical based propensity score in covid-19 vaccine safety research (Xintong Li)
Thursday – Norwegian registries onto OMOP Common Data Model: mapping challenges and opportunities for pregnancy studies (Elmir Hurley)
Friday – PHAROS, Platform for Harmonizing and Accessing Data in Real-time on Infectious Disease Surveillance Based on OMOP-CDM in Korea (Chungsoo Kim) 

Job Openings

• Peter Rijnbeek and his team at Erasmus University is hiring a Secretary for the Darwin EU Coordination Center and Department of Medical Informatics. This position will be responsible for the day-to-day administrative tasks as the personal assistant for Peter Rijnbeek, and will also work as senior secretary for the Department of Medical Informatics, where you will support the staff together with a very experienced colleague. You will play a key role in enabling the research and education delivered by the department. Your work will include the usual responsibilities of a senior secretary such as managing agendas, handing the communication lines, managing changes in personnel, organizing (international meetings and conferences), etc. More information and an application link are available here, and the deadline is Aug. 14, 2022.

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

CDM Update Process (Clair Blacketer, Paul Nagy, Davera Gabriel)

The July 19 OHDSI Community Call featured a new set of workgroup updates:

• Early-Stage Researchers (Faaizah Arshad)
• NLP (Hua Xu)
• Phenotype Development & Evaluation (Gowtham Rao)
• HADES (Martijn Schuemie)

Each of the updates are available at the bottom of this section

Community Updates

• Congratulations to the team of Nicholas Tatonetti and Nick Giangreco on the publication of A database of pediatric drug effects to evaluate ontogenic mechanisms from child growth and development in Med. 

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• EHDEN recently announced that 32 applicants from its most recent data partner call have been selected to join the federated data network, which already includes 134 data partners from 26 countries.

• The most recent Asia-Pacific (APAC) community call focused on two of the ongoing APAC network studies: Characterization of Health by OHDSI AP chapter to identify Temporal Effect of the Pandemic (Seng Chan You), and Data quality of OHDSI APAC: CDM Inspection study (Chungsoo Kim). A recording of the presentation is available here: https://youtu.be/h7dCyzjOWoQ. The next APAC call will focus on the other two studies and will be held July 28.

• Videos from all presentations during the main day of the OHDSI European Symposium are now available.

• The latest edition of The Journey Newsletter, which includes updates on the European Symposium, the SNOMED agreement, the 10-minute tutorials, as well as community updates, publications and presentations, is now available here.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Miniaturizing Data Harmonization; Methods to Facilitate Training in the OMOP Data Ecosystem (Emma Gesquiere)
Tuesday – TrajectoryViz: Interactive visualization of treatment trajectories (Maarja Pajusalu)
Wednesday – OMOP project evolvement at Technische Universität Dresden over the past years (Ines Reinecke)
Thursday – Pharmacological treatment pathways of chronic cough in adults in primary care in the Netherlands: A population-based study (Johnmary Arinze, Solomon Ioannou)
Friday – De-identification of Clinical Notes for Patients with Infectious Disease and Topic Modeling using Latent Dirichlet Allocation (Junhyuk Chang)

Job Openings

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Early-Stage Researchers | NLP | Phenotype Development & Evaluation | HADES | Community Updates

Video Presentation

Early-Stage Researchers (Faaizah Arshad)

NLP (Hua Xu)

Phenotype Development & Evaluation (Gowtham Rao)

HADES (Martijn Schuemie)

The July 12 OHDSI Community Call focused on new adopters and/or new community members. We were excited to hear from 22 people from around the world who are beginning their OHDSI journey. 

You can hear their backgrounds, research interests and ways they hope to enhance the community in the video presentation below.

Community Updates

• Congratulations to the team of Ines Reinecke, Mirko Gruhl, Martin Pinnau, Fatma Betül Altun, Michael Folz, Michéle Zoch, Franziska Bathelt, and Martin Sedlmayr on the recent publication of An OHDSI ATLAS Extension to Support Feasibility Requests in a Research Network in Volume 295 of Studies in Health Technology and Informatics.

• Congratulations to the team of Anthony Molinaro and Frank DeFalco on the publication of Empirical assessment of alternative methods for identifying seasonality in observational healthcare data in BMC Medical Research Methodology.

• Congratulations to the team of Gayathri Delanerolle, Robert Williams, Ana Stipancic, Rachel Byford, Anna Forbes, Sneha Anand, Declan Bradley, Ruby Tsang, Siobhán Murphy, Ashley Akbari, Stuart Bedston, Ronan Lyons, Rhiannon Owen, Jillian Beggs, Antony Chuter, Domnique Balharry, Mark Joy, Aziz Sheikh, F.D. Richard Hobbs, and Simon de Lusignan on the publication of Methodological issues for using a common data model (CDM) of COVID-19 vaccine uptake and important adverse events of interest (AEIs): the Data and Connectivity COVID-19 Vaccines Pharmacovigilance (DaC-VaP) United Kingdom feasibility study in JMIR Formative Research.

• Congratulations to the team of Yae Won Tak, Seng Chan You, Jeong Hyun Han, Soon-Seok Kim, Gi-Tae Kim and Yura Lee on the publication of Perceived Risk of Re-Identification in OMOP-CDM Database: A Cross-Sectional Survey in the Journal of Korean Medical Science.

• Congratulations to the team of Erica Voss, Saberi Rana Ali, Arun Singh, Peter Rijnbeek, Martijn Schuemie, and Daniel Fife on the publication of Hip Fracture Risk After Treatment with Tramadol or Codeine: An Observational Study in Drug Safety.

• Congratulations to the team of Emily Pfaff, Andrew Girvin, Tellen Bennett, Abhishek Bhatia, Ian Brooks, Rachel Deer, Jonathan Dekermanjian, Sarah Elizabeth Jolley, Michael Kahn, Kristin Kostka, Julie McMurry, Richard Moffitt, Anita Walden, Christopher Chute, Melissa A Haendel, and the N3C Consortium on the recent publication of Identifying who has long COVID in the USA: a machine learning approach using N3C data in The Lancet Digital Health.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• Videos from all presentations during the main day of the OHDSI European Symposium are now available.

• The latest edition of The Journey Newsletter, which includes updates on the European Symposium, the SNOMED agreement, the 10-minute tutorials, as well as community updates, publications and presentations, is now available here.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Mapping concepts from the Netherlands Cancer Registry to the OMOP-CDM – experiences and challenges (Chiara Attanasio)
Tuesday – The journey from central operational data-lake to Medica Centers CDM network (Guy Livne)
Wednesday – Informativeness of clinical lymph node metastasis staging for patients undergoing curative intended surgery for colorectal cancer: A national multi-register study (Andreas Weinberger Rosen)
Thursday – Concept extraction from Dutch clinical text (Tom Seinen)
Friday – OHDSI Italia: the Italian national node of OHDSI Europe (Lucia Sacchi)

Job Openings

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

New Community Member Introductions

The June 28 OHDSI Community Call, featured a full review of the 2022 OHDSI European Symposium! 

Nigel Hughes, Director, Observational Health Data Analytics at Janssen Research & Development, provided a review of the 2022 OHDSI European Symposium, held June 24-26 in Rotterdam. This presentation highlights the panels, talks and collaborator showcase from Day 1, and it also includes details on the Day 2 and Day 3 workshops.

Keep following OHDSI.org for more information on the European Symposium, including recordings from all events when they are available.

There will be no community call on July 5.

Community Updates

• Thank you to everybody who submitted brief reports to join our #OHDSI2022 Collaborator Showcase. We had a record amount (more than 130!) of submissions for poster presentations, software demos and oral presentations for the 2022 OHDSI Symposium, which will be held Oct. 14-16 in Bethesda, Md. The scientific committee meets this week to begin the process of reviewing all submissions, and selected presenters will be notified by August 1, 2022.

• Our July 12 Community Call will be focused on new adopters of the OMOP CDM or new members of the OHDSI community. We are welcoming people to introduce themselves, share why they have joined the community and what impact they hope to make, and also ask a question to the broader community. If you would like to take part in this event, please fill out this form to help us plan the session.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Why predicting risk can’t identify ‘risk factors’: empirical assessment of model stability in machine learning across observational health databases (Aniek Markus)
Tuesday – OMOP Genomic mapping capacities in conversion of comprehensive genomic profiling results (Maria Rogozhkina)
Wednesday – Perseus Design and run your own ETL to CDM (Anton Ivanov)
Thursday – Using geospatial approaches and machine learning for asthma and COPD outcomes: a systematic review (Daniel Jeannetot)
Friday – A pilot study to evaluate the feasibility of using Observational Health Data Sciences and Informatics analytics tools for supporting the validation of safety signals (Ceyda Pekmez)

• On behalf of the Health Systems Special Interest Group, lead Melanie Philofsky shared this recent forum post requesting assistance in a creating central repository of different OMOP sites, their underlying EHR system, and attributes. If you can add to this repository and enhance community knowledge, please fill out this form.

• As mentioned during the video presentation below, the launch of the EHDEN Portal was announced during the European Symposium. The Portal includes a Data Partner Catalogue and Feasibility Dashboards that support data discoverability (findable under Findable, Accessible, Interoperable and Reusable (FAIR) principles). The Portal represents the start of an open platform to facilitate identifying data that is likely to be used for a research topic, through the study workflow to analytical results. It gives researchers more granular insights into EHDEN’s 140-strong Data Partner network with currently more than 500 million anonymous patient records being mapped to the OMOP common data model local to the data.

Job Openings

• Odysseus Data Services posted two new openings recently. There are currently openings for an epidemiologist and a data scientist. Please check out the links for more information and/or to apply for these jobs.

• Professor Peter Rijnbeek announced an opening for an epidemiologist to work with his team at Erasmus MC. This position will be responsible for all aspects of observational research including protocol writing, input in the statistical analysis plan, study execution, interpretation of results and report/manuscript writing. The application deadline is July 8, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

European Symposium Review | Community Updates

Video Presentation

European Symposium Review (Nigel Hughes)

The June 21 OHDSI Community Call featured four 10-minute tutorials on open-source tools developed within our community for use in global research initiatives: 

PheValuator
Presenter: Joel Swerdel • Associate Director, Johnson & Johnson

PheKnowLater
Presenter: Tiffany Callahan • Postdoctoral Research Fellow, Columbia University

Patient-Level Prediction
Presenter: Jenna Reps • Associate Director, Johnson & Johnson

CAPR (Cohort definition Application Programming in R)
Presenter: Martin Lavallee • Data Scientist, Odysseus Data Services

Community Updates

• Showcase submission week has arrived! All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

Congratulations to the team of Jiayi Tong, Chongliang Luo, Md Nazmul Islam, Natalie E. Sheils, John Buresh, Mackenzie Edmondson, Peter A. Merkel, Ebbing Lautenbach, Rui Duan and Yong Chen on the publication of Distributed learning for heterogeneous clinical data with application to integrating COVID-19 data across 230 sites in Digital Medicine.

• Congratulations to the team of Emmanuel Uchenna Agu, Arman Mosenia, Jacob A Lifton, Lawrence Chan, Katherine G Ligtenberg, Drew Saylor, Reza Vagefi, Seanna R Grob, Robert Kersten, Melena Ahmad, and Bryan Winnon on the publication of The Impact of COVID-19 on Periocular Non-Melanoma Skin Cancer in the Veteran Population in Investigative Ophthalmology & Visual Science.

• Congratulations to the team of Yongseok Mun, ChulHyoung Park, Da Yun Lee, Tong Min Kim, Ki Won Jin, Seok Kim, Yoo-Ri Chung, Kihwang Lee, Ji Hun Song, Young-Jung Roh, Donghyun Jee, Jin-Woo Kwon, Se Joon Woo, Kyu Hyung Park, Rae Woong Park, Sooyoung Yoo, Dong-Jin Chang & Sang Jun Park on the publication of Real-world treatment intensities and pathways of macular edema following retinal vein occlusion in Korea from Common Data Model in ophthalmology in Scientific Reports.

• Congratulations to the team of Sooyoung Yoo, Eunsil Yoon, Dachung Boo, Borham Kim, Seok Kim, Jin Chul Paeng, Ie Ryung Yoo, In Young Choi, Kwangsoo Kim, Hyun Gee Ryoo, Sun Jung Lee, Eunhye Song, Young-Hwan Joo, Junmo Kim, and Ho-Young Lee on the publication of Transforming Thyroid Cancer Diagnosis and Staging Information from Unstructured Reports to the Observational Medical Outcome Partnership Common Data Model in Applied Clinical Informatics.

• Congratulations to the team of Cynthia Yang, Ross Williams, Joel Swerdel, João Rafael Almeida, Emily S. Brouwer, Edward Burn, Loreto Carmona, Katerina Chatzidionysiou, Talita Duarte-Salles, Walid Fakhouri, Antje Hottgenroth, Meghna Jani, Raivo Kolde, Jan A. Kors, Lembe Kullamaa, Jennifer Lane, Karine Marinier, Alexander Michel, Henry Morgan Stewart, Albert Prats-Uribe, Sulev Reisberg, Anthony Sena, Carmen Torre, Katia Verhamme, David Vizcaya, James Weaver, Patrick Ryan, Daniel Prieto-Alhambra, and Peter Rijnbeek on the publication of Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis in Seminars in Arthritis and Rheumatism.

• Congratulations to the team of Anna Ostropolets, Patrick Ryan, Martijn Schuemie, and George Hripcsak on the publication of Characterizing Anchoring Bias in Vaccine Comparator Selection Due to Health Care Utilization With COVID-19 and Influenza: Observational Cohort Study in JMIR Public Health and Surveillance.

• Congratulations to OHDSI veteran and Australia Chapter lead Nicole Pratt, who was recent named one of eight new ISPE Fellows for 2022. Nicole, whose interest in the effectiveness and safety of medicine use has led her to collaborate on network initiatives like LEGEND and EUMAEUS, was featured in the latest edition of the OHDSI Collaborator Spotlight.

• On behalf of the Health Systems Special Interest Group, lead Melanie Philofsky shared this recent forum post requesting assistance in a creating central repository of different OMOP sites, their underlying EHR system, and attributes. If you can add to this repository and enhance community knowledge, please fill out this form.

• Our July 12 community call will focus on new adopters of OMOP and/or new members of the community. We are looking for people to introduce themselves, and offering an opportunity to ask questions to the community. If you would like to be part of this call, please let us know!

Job Openings

• Odysseus Data Services posted two new openings recently. There are currently openings for an epidemiologist and a data scientist. Please check out the links for more information and/or to apply for these jobs.

• Professor Peter Rijnbeek announced an opening for an epidemiologist to work with his team at Erasmus MC. This position will be responsible for all aspects of observational research including protocol writing, input in the statistical analysis plan, study execution, interpretation of results and report/manuscript writing. The application deadline is July 8, 2022.

• Professor Dani Prieto-Alhambra announced an opening for a postdoctoral data scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. The application deadline is June 27, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

PheValuator | PheKnowLator | CAPR | Community Updates

Video Presentations

PheValuator (Joel Swerdel)

PheKnowLator (Tiffany Callahan)

Patient-Level Prediction (Jenna Reps)

Cohort definition Application Programming in R (Martin Lavallee)

Our OHDSI community produced nearly 40 peer-reviewed and published studies over the first five months of 2022, and five of the study leads were presented during our June 14 community call.

Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort
Presenter: Yuan Lu • Assistant Professor, Yale University

Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases
Presenter: Anna Ostropolets • PhD Student, Columbia University

Logistic regression models for patient-level prediction based on massive observational data: Do we need all data?
Presenter: Henrik John • PhD Student, Erasmus University

Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability
Presenter: Jenna Reps • Associate Director, Johnson & Johnson

Prior-Preconditioned Conjugate Gradient Method for Accelerated Gibbs Sampling in “Large n, Large p” Bayesian Sparse Regression
Presenter: Aki Nishimura • Assistant Professor, Johns Hopkins University

Community Updates

• Congrats to the team of Rohan Khera, Martijn Schuemie , Yuan Lu , Anna Ostropolets, RuiJun Chen, George Hripcsak, Patrick Ryan, Harlan Krumholz, and Marc Suchard on the recent publication of Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studies in BMJ Open.

• Congratulations to the team of Paul Heidera, Ronak Pipaliyab, and Stéphane Meystre on the publication of A Natural Language Processing Tool Offering Data Extraction for COVID-19 Related Information (DECOVRI) in Volume 290 of Studies in Health Technology and Informatics.

• Congratulations to the team of Lamy Jean-Baptistea, Abdelmalek Mouazera, Karima Sedkia, and Rosy Tsopra on the publication of Translating the Observational Medical Outcomes Partnership – Common Data Model (OMOP-CDM) Electronic Health Records to an OWL Ontology in Volume 290 of Studies in Health Technology and Informatics.

• Congratulations to the team of Mélanie Buy, William Digan, Xiaoyi Chen, Julien Husson, Mickael Ménager, Frédéric Rieux Laucat, Nicolas Garcelon, and ATRACTion members on the publication of A Multi-Omics Common Data Model for Primary Immunodeficiencies in Volume 290 of Studies in Health Technology and Informatics.

• The latest edition of the OHDSI Collaborator Spotlight focuses on community veteran and Australia chapter lead Nicole Pratt, whose interest in the effectiveness and safety of medicine use has led her to collaborate on network initiatives like LEGEND and EUMAEUS. She has also played an important role in the continued growth of the APAC community. She shares about her journey to OHDSI, her roles in the community and more in this spotlight.

• The OHDSI community and SNOMED International have formalized their long-time relationship with a five-year collaborative agreement that will benefit both of their user communities. The SNOMED collaboration provides OHDSI and its user community with comprehensive ontologies on specific healthcare domains and content such as devices, social determinants of health, disease severity scores and modifiers of cancers, as well as better concept definitions and resolutions of composite concepts in large-scale observational research. In return, OHDSI and its user community can provide SNOMED International with information and feedback on clinical validation, frequency of use data, and validation of SNOMED CT content modeling. Learn more in the full media release.

• The CBER Best Seminar Series is being rescheduled moving forward. Please be on the lookout for more information on when it will resume and who will be added to the schedule.

• We are less than two weeks away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage. 

Job Openings

• Professor Peter Rijnbeek announced an opening for an epidemiologist to work with his team at Erasmus MC. This position will be responsible for all aspects of observational research including protocol writing, input in the statistical analysis plan, study execution, interpretation of results and report/manuscript writing. The application deadline is July 8, 2022.

• Professor Dani Prieto-Alhambra announced an opening for a postdoctoral data scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. The application deadline is June 27, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Lu | Ostropolets | John | Reps | Nishimura | Community Updates

Video Presentations

Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort (Lu)

Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases (Ostropolets)

Logistic regression models for patient-level prediction based on massive observational data: Do we need all data? (John)

Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability (Reps)

Prior-Preconditioned Conjugate Gradient Method for Accelerated Gibbs Sampling in “Large n, Large p” Bayesian Sparse Regression (Nishimura)

Patrick Ryan and Craig Sachson provided an overview of the OHDSI community, a tour of the OHDSI website and Teams environment, and a preview of the OHDSI Symposium collaborator showcase. Paul Nagy shared his journey to the community, and there was a brief Q&A session.

For all newcomers to the community, we will have a community call on July 12 focused on meeting new adopters of OMOP and answering any questions you might have.

Community Updates

• Congratulations to the team of Azza Shoaibi, Gowtham Rao, Erica Voss, Anna Ostropolets, Miguel Angel Mayer, Juan Manuel Ramírez-Anguita, Filip Maljković, Biljana Carević, Scott Horban, Daniel R. Morales, Talita Duarte-Salles, Clement Fraboulet, Tanguy Le Carrour, Spiros Denaxas, Vaclav Papez, Luis H. John, Peter R. Rijneek, Evan Minty, Thamir M. Alshammari, Rupa Makadia, Clair Blacketer, Frank DeFalco, Anthony Sena, Marc Suchard, Daniel Prieto-Alhambra and Patrick Ryan on the publication of Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thromlbocytopenia in Real World Data: A Multinational Network Cohort Study in Drug Safety.

• The OHDSI community and SNOMED International have formalized their long-time relationship with a five-year collaborative agreement that will benefit both of their user communities. The SNOMED collaboration provides OHDSI and its user community with comprehensive ontologies on specific healthcare domains and content such as devices, social determinants of health, disease severity scores and modifiers of cancers, as well as better concept definitions and resolutions of composite concepts in large-scale observational research. In return, OHDSI and its user community can provide SNOMED International with information and feedback on clinical validation, frequency of use data, and validation of SNOMED CT content modeling. Learn more in the full media release.

• The June edition of the OHDSI newsletter is now available. This edition includes the DARWIN EU presentation and corresponding slides, a collaborator spotlight on Asieh Golozar, the latest on open studies in the global community, the monthly update podcast and other community updates, all publications and presentation from May, and plenty more. If you aren’t already a subscriber, you can do so here.

• The CBER Best Seminar Series is being rescheduled moving forward. Please be on the lookout for more information on when it will resume and who will be added to the schedule.

• We are less one month away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

Job Openings

• Professor Dani Prieto-Alhambra announced an opening for a Postdoctoral Data Scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. It will carry out collaborative research projects with colleagues in partner institutions and report research findings in the form of conference abstracts at national and international conferences. You can learn more and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Welcome To OHDSI | Community Updates

Video Presentation

Leads from the OHDSI workgroups joined the May 31 Community Call to go around and present what is happening within their respective teams in relation to 2022 objectives and key results. This was an opportunity for the community to learn about all the current work happening around our community and to see how you can collaborate with our workgroups to achieve these goals.

Community Updates

• Congratulations to the team of Jenna Reps, Ross Williams, Martijn Schuemie, Patrick Ryan & Peter Rijnbeek on the publication of Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability in BMC Medical Informatics and Decision Making. 

• Congratulations to the team of Elisa Henke, Ines Reinecke, Michele Zoch, Martin Sedlmayr, and Franziska Bathelt on the publication of Towards the Improvement of Clinical Guidelines Based on Real World Data in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Jose Manuel Saborit-Torres, Silvia Nadal-Almela, Joaquim Angel Montell-Serrano, Elena Oliver-Garcia, Hector Carceller, Jon Ander Gómez-Ádrian, Marisa Caparrós-Redondo, Francisco García-García, Julio Domenech-Fernández and Maria De La Iglesia-Vayá on the publication of Beyond the Brain: MIDS Extends BIDS to Multiple Modalities and Anatomical Regions in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Ines Reinecke, Michael Kallfelz, Martin Sedlmayr, Joscha Siebel and Franziska Bathelt on the publication of Evaluation and Challenges of Medical Procedure Data Harmonization to SNOMED-CT for Observational Research in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Daniel Puttmann, Nicolette De Keizer, Ronald Cornet, Eric Van Der Zwan, Ferishta Bakhshi-Raiez on the publication of FAIRifying a Quality Registry Using OMOP CDM: Challenges and Solutions in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Emmanuelle Theron, Jean-François Gorse, and Xavier Gansel on the publication of Usability of OMOP Common Data Model for Detailed Lab Microbiology Results in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Franziska Bathelt, Ines Reinecke, Yuan Peng, Elisa Henke, Jens Weidner, Martin Bartos, Robert Gött, Dagmar Waltemath, Katrin Engelmann, Peter Schwarz, and Martin Sedlmayr on the publication of Opportunities of Digital Infrastructures for Disease Management—Exemplified on COVID-19-Related Change in Diagnosis Counts for Diabetes-Related Eye Diseases in Nutrients.

• We are less one month away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

Job Openings

• Professor Dani Prieto-Alhambra announced an opening for a Postdoctoral Data Scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. It will carry out collaborative research projects with colleagues in partner institutions and report research findings in the form of conference abstracts at national and international conferences. You can learn more and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates & OKRs

Video Presentations

Around The Workgroups

The May 24 OHDSI Community Call shared six open studies that are ongoing in our global network:

IBD characterization
Presenter: Chen Yanover

Characterization of Health by OHDSI Asia-Pacific chapter to identify Temporal Effect of the Pandemic (CHAPTER) Study
Presenter: Seng Chan You

Applying the Decentralized Generalized Linear Mixed Effects Model (dGEM) for Hospital Profiling of COVID-19 Mortality Data across OHDSI Network
Presenter: Jessie Tong

Real world safety of treatments for multiple sclerosis
Presenter: Nicole Pratt

Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19
Presenter: Ivan Lam

Quality assessment of CDM databases across the OHDSI-AP network
Presenter: Chungsoo Kim

Community Updates

• Congratulations to the team of Emily Pfaff, Andrew Girvin, Tellen Bennett, Abhishek Bhatia, Ian Brooks, Rachel Deer, Jonathan Dekermanjian, Sarah Elizabeth Jolley, Michael Kahn, Kristin Kostka, Julie McMurry, Richard Moffitt, Anita Walden, Christopher Chute, Melissa Haendel, and the N3C Consortium on the publication of Identifying who has long COVID in the USA: a machine learning approach using N3C data in The Lancet Digital Health.

• Congratulations to the team of Jin Ge, W. Ray Kim, Jennifer Lai, and Allison Kwong on the publication of “Beyond MELD” – Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation in the Journal of Hepatology.

• Congratulations to the team of Justin T. Reese, Ben Coleman, Lauren Chan, Hannah Blau, Tiffany J. Callahan, Luca Cappelletti, Tommaso Fontana, Katie R. Bradwell, Nomi L. Harris, Elena Casiraghi, Giorgio Valentini, Guy Karlebach, Rachel Deer, Julie A. McMurry, Melissa A. Haendel, Christopher G. Chute, Emily Pfaff, Richard Moffitt, Heidi Spratt, Jasvinder A. Singh, Christopher J. Mungall, Andrew E. Williams & Peter N. Robinson for the publication of NSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study in Virology Journey.

• We are approximately one month away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

• The CDM Workshop that was supposed to be held last Thursday, May 19, has been moved to this Thursday, May 26 (1 pm ET). It will focus on ETL Vocabulary Mapping. If you are interested in taking part, please fill out this form.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

• EHDEN is now hosting its sixth open call for data partners looking to map their patient data to the OMOP CDM. Through its first five open calls, EHDEN has created a federated data network of 140 partners across 26 countries, and it has also trained and certified 47 SMEs to assist with mapping this data. Data Partners can benefit from up to a maximum of €100 000 funding. The deadline to apply is June 14, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase

Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 – Workgroup Activities: Information | Registration

Slides 

Yanover | You | Tong | Pratt | Lam | Kim | Community Updates

Video Presentations

IBD characterization (Yanover)

Characterization of Health by OHDSI Asia-Pacific chapter to identify Temporal Effect of the Pandemic (CHAPTER) Study (You)

https://https://youtu.be/swSC-IQdXms

Applying the Decentralized Generalized Linear Mixed Effects Model (dGEM) for Hospital Profiling of COVID-19 Mortality Data across OHDSI Network (Tong)

Real world safety of treatments for multiple sclerosis (Pratt)

Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19 (Lam)

Applying the DecentraQuality assessment of CDM databases across the OHDSI-AP network (Kim)

The May 17 OHDSI Community Call brought back a popular format, the OHDSI Debates. We hosted two debates and had the community vote on the winner!

Debate 1: Phenotype Development: One-size-fits-all vs. Tailored-per-databases

Debaters: Azza Shoaibi (Associate Director, Janssen Research & Development) and Asieh Golozar (VP, Global Head of Data Science, Odysseus Data Services, Inc.)

Debate 2: Study Diagnostics: Nice-to-have vs. Essential requirements

Debaters: Dani Prieto-Alhambra (Professor, Univ. of Oxford and Erasmus Univ.) and Martijn Schuemie (Research Fellow, Epidemiology Analytics, Janssen Research & Development

Community Updates

• Congratulations to the team of Justin Reese, Ben Coleman, Lauren Chan, Hannah Blau, Tiffany J. Callahan, Luca Cappelletti, Tommaso Fontana, Katie R. Bradwell, Nomi L. Harris, Elena Casiraghi, Giorgio Valentini, Guy Karlebach, Rachel Deer, Julie A. McMurry, Melissa A. Haendel, Christopher G. Chute, Emily Pfaff, Richard Moffitt, Heidi Spratt, Jasvinder A. Singh, Christopher J. Mungall, Andrew E. Williams & Peter N. Robinson on the publication of NSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study in Virology Journal.

• Congratulations to the team of Edward Burn, Talita Duarte-Salles, Sergio Fernandez-Bertolin, Carlen Reyes, Kristin Kostka, Antonella Delmestri, Peter Rijnbeek, Katia Verhamme, and Daniel Prieto-Alhambra on the publication of Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study in The Lancet Infectious Diseases.

• The next CDM Workshop will be held inside MS Teams this Thursday, May 19 (1 pm ET), and it will focus on ETL Vocabulary Mapping. If you are interested in taking part, please fill out this form.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

• EHDEN is now hosting its sixth open call for data partners looking to map their patient data to the OMOP CDM. Through its first five open calls, EHDEN has created a federated data network of 140 partners across 26 countries, and it has also trained and certified 47 SMEs to assist with mapping this data. Data Partners can benefit from up to a maximum of €100 000 funding. The deadline to apply is June 14, 2022.

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase

Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 – Workgroup Activities: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Video Presentations

Debate 1: Phenotype Development: One-size-fits-all vs. Tailored-per-databases (Shoaibi vs. Golozar)

Debate 2: Study Diagnostics: Nice-to-have vs. Essential requirements (Schuemie vs. Prieto-Alhambra)

The May 10 Community Call featured three Mother’s Day-themed conversations, facilitated by members of our community. There were discussions around clinical research opportunities, community building and data standards, and they were meant to be open conversations to address challenges within our community and/or the healthcare field.

The three discussions (all of which are posted below) and facilitators were:

Clinical Research Opportunities: Brainstorm on maternal health
– Alison Callahan, Research Scientist, Stanford Center for Biomedical Informatics
 – Ru-fong Cheng, Senior Medical Director, Women’s Health, Office of the Chief Medical Officer, Johnson & Johnson
 – Noémie Elhadad, Associate Professor of Biomedical Informatics; Vice Chair, Research, Columbia Department of Biomedical Informatics

How can OHDSI support collaborator mothers to advance their personal and professional development?
– Rupa Makadia, Associate Director, Epidemiology Analytics, Janssen Research and Development
 – Sarah Seager, Director of Data Science, OMOP at IQVIA

Recommended best practices for modeling pregnancy episodes and mother-child linkage
– Jill Hardin, Associate Director, Epidemiology Analytics, Janssen Research and Development
 – Mui Van Zandt, VP & GM Real World Data & Tech, IQVIA 

Community Updates

• Congratulations to the team of Fatemeh Amrollahi, Supreeth P Shashikumar, Angela Meier, Lucila Ohno-Machado, Shamim Nemati, and Gabriel Wardi on the publication of Inclusion of social determinants of health improves sepsis readmission prediction models in JAMIA.

• Registration is now open for workgroup activities and meetings during the weekend of the 2022 OHDSI Global Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. Check out this page for descriptions and times of all meetings, and then register for any meetings you would like to join (these meetings are free, but registration is important because this will be first-come, first-served due to room capacity).

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org.

• Last week’s APAC Community Call included a presentation from Gowtham Rao on how to take advantage of the cohort diagnostics tool using one of the ongoing APAC studies as an example. You can find the recording on the APAC Community page.

• It was also announced on the last APAC call that the 2022 OHDSI APAC Symposium will be held Nov. 12-13 in Taipei, Taiwan. There will be both an on-site and virtual component to this event. Please follow the APAC Community page for more information.

• The latest OHDSI newsletter is now available, and it includes all the key information from DevCon, links to 10 community publications from April, details on the Sponsorship Program and other updates. If you don’t receive the monthly newsletter, you can subscribe to it here.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

Openings

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here.

• As mentioned by Sally Baxter and Kerry Goetz during a recent community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

• Cynthia Sung shared a recent summer internship opportunity in the Bill & Melinda Gates Medical Research Institute. One internship of potential interest to the community is seeking a candidate in the areas of computational biology, computer science or bioengineering major who is proficient in coding in SQL and R or Python to transform Tuberculosis clinical trial data into the OMOP CDM. More information and an application link are available here.

• Daniel Smith shared a recent opening at Emory University in Atlanta for an Informatics Analyst; this position will provide OMOP support for Winship Data and Winship Discovery projects. You can learn more about this project and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 — Workshop Activities: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Community Updates

Video Presentations

Clinical Research Opportunities: Brainstorm on maternal health (Alison Callahan, Ru-fong Cheng, Noémie Elhadad)

How can OHDSI support collaborator mothers to advance their personal/professional development? (Rupa Makadia, Sarah Seager)

Recommended best practices for modeling pregnancy episodes and mother-child linkage (Jill Hardin, Mui Van Zandt)

The May 3 Community Call focused on the DARWIN EU Initiative, as well as how the OHDSI community can impact this new push towards using real-world evidence to impact healthcare.

The vision of DARWIN EU is to give the European Medicines Agency and national competent authorities in EU Member States access to valid and trustworthy real-world evidence, for example on diseases, patient populations, and the use, safety and effectiveness of medicines, including vaccines, throughout the lifecycle of a medicinal product.

The Erasmus Medical Center has earned the contract as the coordinating center for DARWIN EU. Peter Rijnbeek, Head of the Department of Medical Informatics at Erasmus Medical Center, led this presentation about the DARWIN EU mission and five-year plan, the role of the coordinating center, and how OHDSI tools and standards can and will impact this initiative.

Community Updates

• Congratulations to the team of Anna Ostropolets, Xintong Li, Rupa Makadia, Gowtham Rao, Peter Rijnbeek, Talita Duarte-Salles, Anthony Sena, Azza Shaoibi, Marc Suchard, Patrick Ryan, Daniel Prieto-Alhambra and George Hripcsak on the publication of Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases in Frontiers of Pharmacology.

• Congratulations to the team of Juan Quiroz, Tim Chard, Zhisheng Sa, Angus Ritchie, Louisa Jorm and Blanca Gallego on the publication of Extract, transform, load framework for the conversion of health databases to OMOP in PLOS One.

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org. A big announcement from DevCon was the formation of the Khieron Contributor Cohort, which will help onboard and mentor open-source developers in the community. If you are interested in joining the effort, please fill out this application; the deadline is THIS FRIDAY, May 6.

• This week’s APAC Community Call (May 5 in the Eastern Hemisphere, May 4 in the Western Hemisphere) will include a presentation from Gowtham Rao, who will present how to take advantage of the cohort diagnostics tool using one of the ongoing APAC studies as an example. You can get the call invitation by joining the APAC Workgroup, or you can find the link or access the recording afterwards on the APAC Community page.

• The latest OHDSI newsletter is now available, and it includes all the key information from DevCon, links to 10 community publications from April, details on the Sponsorship Program and other updates. If you don’t receive the monthly newsletter, you can subscribe to it here.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

Openings

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here.

• As mentioned by Sally Baxter and Kerry Goetz during a recent community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

• Cynthia Sung shared a recent summer internship opportunity in the Bill & Melinda Gates Medical Research Institute. One internship of potential interest to the community is seeking a candidate in the areas of computational biology, computer science or bioengineering major who is proficient in coding in SQL and R or Python to transform Tuberculosis clinical trial data into the OMOP CDM. More information and an application link are available here.

• Daniel Smith shared a recent opening at Emory University in Atlanta for an Informatics Analyst; this position will provide OMOP support for Winship Data and Winship Discovery projects. You can learn more about this project and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

DARWIN EU | Community Updates

Video Presentation

The April 26 Community Call, focused on the state of the OHDSI open-source community, and it included a recap on the first OHDSI DevCon, held April 22. We also heard about a new opportunity in open-source development that was announced during the State of the Community presentation (more on this below).

We heard from the following leaders in our open-source community:

• Lee Evans (Owner • LTS Computing LLC) 
• Martijn Schuemie (Research Fellow, Epidemiology Analytics • Janssen Research and Development)
• Paul Nagy (Associate Professor • Johns Hopkins School of Medicine)
• Adam Black (Data Sciences • Odysseus Data Services)

Community Updates

• Congratulations to the team of Yilu Fang, Betina Idnay, Yingcheng Sun, Hao Liu, Zhehuan Chen, Karen Marder, Hua Xu, Rebecca Schnall, and Chunhua Weng on the publication of Combining human and machine intelligence for clinical trial eligibility querying in JAMIA.

• Congratulations to the team of Katie Bradwell, Jacob Wooldridge, Benjamin Amor, Tellen Bennett, Adit Anand, Carolyn Bremer, Yun Jae Yoo, Zhenglong Qian, Steven Johnson, Emily Pfaff, Andrew Girvin, Amin Manna, Emily Niehaus, Stephanie Hong, Xiaohan Tanner Zhang, Richard Zhu, Mark Bissell, Nabeel Qureshi, Joel Saltz, Melissa Haendel, Christopher Chute, Harold Lehmann, and Richard Moffitt (on behalf of the N3C Consortium) on the publication of Harmonizing units and values of quantitative data elements in a very large nationally pooled electronic health record (EHR) dataset in JAMIA.

• Congratulations to the team of Kristina Bardenheuer, Michel Van Speybroeck, Clare Hague, Enkeleida Nikai, and Martin Price on the publication of Haematology Outcomes Network in Europe (HONEUR) – a collaborative, interdisciplinary platform to harness the potential of Real-World Data in hematology in the European Journal of Haematology.

• OHDSI DevCon 2022 was a success last Friday, with more than 100 people joining for a series of workshops, talks and an impressive final panel discussion. All the talks will be loaded to the DevCon homepage on OHDSI.org, but both the State of the Community presentation by Adam Black and Paul Nagy, as well as the Keynote Address by Martijn Schuemie, are currently on the page. A big announcement from DevCon was the formation of the Khieron Contributor Cohort, which will help onboard and mentor open-source developers in the community. If you are interested in joining the effort, please fill out this application.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

• The most recent APAC Community Call featured APAC Studies quarterly updates. You can access the recording afterwards, on the APAC Community page.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Openings

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here. The application deadline is this Wednesday, April 27.

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• As mentioned by Sally Baxter and Kerry Goetz on last week’s community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

Slides

Community Updates

Video Presentation

The April 19 OHDSI Community Call featured a new set of workgroup updates, including an introduction of a brand new workgroup (Eye Care and Vision Research):

• Eye Care and Vision Research (Sally Baxter, Assistant Professor, Division Chief for Ophthalmology Informatics and Data Science, UC San Diego)
• FHIR and OMOP (Christian Reich, Vice President, RWE Systems • IQVIA)
• Oncology (Asieh Golozar, VP, Global Head of Data Science • Odysseus Data Services)
• Steering Group (Jody-Ann McLeggon • Program Manager, Columbia University)

Community Updates

• Congratulations to the team of Henrik John, Jan Kors, Jenna Reps, Patrick Ryan, and Peter Rijnbeek on the publication of Logistic regression models for patient-level prediction based on massive observational data: Do we need all data? in the International Journal of Medical Informatics.

• Congratulations to the team of Yilu Fang, Betina Idnay, Yingcheng Sun, Hao Liu, Zhehuan Chen, Karen Marder, Hua Xu, Rebecca Schnall, and Chunhua Weng on the publication of Combining human and machine intelligence for clinical trial eligibility querying in JAMIA.

• Curious about the new OHDSI Sponsorship program that was announced last week, and how you can help support the community’s global research journey? Check out the OHDSI Sponshorship homepage, which includes the community call presentation from George Hripcsak.

• The next APAC Community Call will be held Thursday, April 21 (Wednesday night in the Western Hemisphere) and will provide APAC Studies quarterly updates. You can get the link for the call, or access the recording afterwards, on the APAC Community page.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now. 

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Eye Care & Vision Research | FHIR & OMOP | Oncology | Steering Group | Community Updates

Videos

Eye Care & Vision Research (Sally Baxter and Kerry Goetz)

FHIR & OMOP (Christian Reich)

Oncology (Asieh Golozar)

Steering Group (Jody-Ann McLeggon)

George Hripcsak, Chair and Vivian Beaumont Allen Professor of Biomedical Informatics at Columbia University, discussed the many ways Columbia DBMI supports OHDSI, and he shares why it will be important to support the coordinating center in the future, as well as what benefits can come from your support. 

Community Updates

• Congratulations to the team of Berta Raventós, Andrea Pistillo, Carlen Reyes, Sergio Fernández-Bertolín, Maria Aragón, Anna Berenguera, Constanza Jacques-Aviñó, Laura Medina-Perucha, Edward Burn, and Talita Duarte-Salles on the publication of Impact of the COVID-19 pandemic on diagnoses of common mental health disorders in adults in Catalonia, Spain: a population-based cohort study in BMJ Open.

• Congratulations to the team of Tae-Hoon Kim, SiHyeong Noh, Youe Ree Kim, ChungSub Lee, Ji Eon Kim, Chang-Won Jeong, and Kwon-Ha Yoon on the publication of Development and validation of a management system and dataset quality assessment tool for the Radiology Common Data Model (R_CDM): A case study in liver disease in the International Journal of Medical Informatics.

• Based on George Hripcsak’s presentation, OHDSI has created both Sponsorship Program and Sponsors pages on the website. Please check them out and see how you can support OHDSI’s growth while receiving several benefits for your organization.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

OHDSI Coordinating Center | Community Updates

Video

Patrick Ryan led the OHDSI community in a game of “Name That Result” (a distant relative of the old Name That Tune game show) where eight contestants were able to showcase all the ways they could get from data to evidence using the OMOP CDM and OHDSI tools. This one was decided on the final question!

Thank you to Michael Cook, Stephanie Hong, Kristin Kostka, Martin Lavallee, Filip Malkovic, Maxim Moinat, Jose Posada, and Katherine Simon for their insights and spirited competition in this game!

Community Updates

• Congratulations to the team of Chongliang Luo, Md Nazmul Islam, Natalie Sheils, John Buresh, Jenna Reps, Martijn Schuemie, Patrick Ryan, Mackenzie Edmondson, Rui Duan, Jiayi Tong, Arielle Marks-Anglin, Jiang Bian, Zhaoyi Chen, Talita Duarte-Salles, Sergio Fernández-Bertolín, Thomas Falconer, Chungsoo Kim, Rae Woong Park, Stephen Pfohl, Nigam Shah, Andrew Williams, Hua Xu, Yujia Zhou, Ebbing Lautenbach, Jalpa Doshi, Rachel Werner, David Asch, and Yong Chen on the publication of DLMM as a lossless one-shot algorithm for collaborative multi-site distributed linear mixed models in Nature Communications.

• Congratulations to the team of Seok Kim, Ji-In Bang, Dachung Boo, Borham Kim, In Young Choi, SooJeong Ko, Ie Ryung Yoo, Kwangsoo Kim, Junmo Kim, YoungHwan Joo, Hyun Gee Ryoo, Jin Chul Paeng, Jung Mi Park, Woncheol Jang, Byungwon Kim, Yangha Chung, Dongyoon Yang, Sooyoung Yoo, and Ho-Young Lee on the publication of Second primary malignancy risk in thyroid cancer and matched patients with and without radioiodine therapy analysis from the observational health data sciences and informatics in European Journal of Nuclear Medicine and Molecular Imaging.

• Both the presentations and slides from the recent community call session on Reproducibility are now available here. This session was led by Anna Ostropolets, Martijn Schemie and Asieh Golozar, and focused on the OHDSI2021 Reproducibility Challenge, how to design reproducible studies, and the Reproducibility Service at the Roux Institute.

• The April edition of the OHDSI Newsletter is now available, and it includes reports on the CDM Workshop, DevCon, and the OHDSI2022 Tutorial, as well as other community updates, links to publications and presentations, and plenty more. If you aren’t already subscribing to the newsletter, you can do so here.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage. 

Slides

Community Updates

Video

The March 29 OHDSI Community Call focused on reproducibility, and three leaders in the community shared presentations on this topic. 

– The 2021 OHDSI Reproducibility Challenge (Anna Ostropolets)
– Developing Reproducible Studies (Martijn Schuemie)
– The OHDSI Reproducibility Service (Asieh Golozar)

Community Updates

• Congratulations to the team of Yuan Lu, Mui Van Zandt, Yun Liu, Jing Li, Xialin Wang, Yong Chen, Zhengfeng Chen, Jaehyeong Cho, Sreemanee Raaj Dorajoo, Mengling Feng, Min-Huei Hsu, Jason C. Hsu, Usman Iqbal, Jitendra Jonnagaddala, Yu-Chuan Li, Siaw-Teng Liaw, Hong-Seok Lim, Kee Yuan Ngiam, Phung-Anh Nguyen, Rae Woong Park, Nicole Pratt, Christian Reich, Sang Youl Rhee, Selva Muthu Kumaran Sathappan, Seo Jeong Shin, Hui Xing Tan, Seng Chan You, Xin Zhang, Harlan M. Krumholz, Marc A. Suchard, and Hua Xu on the publication of Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort in JAMA Network Open.

This is an especially exciting paper, as it is the first to come out of the OHDSI Asia-Pacific (APAC) Workgroup. The APAC team leads a bi-weekly community call, and each is recorded. Last week’s session included a presentation from Christian Reich about the FHIR-OMOP partnership. You can see that recording and get both the link and themes for upcoming calls at the APAC homepage.

• Congratulations to both Aki Nishimura and Marc Suchard on the publication of Prior-preconditioned conjugate gradient method for accelerated Gibbs sampling in ‘large n & large p’ Bayesian sparse regression in the Journal of the American Statistical Association.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. The full agenda has been added. You can register for the event now.

• The recent presentation on “The OHDSI Vocabulary Journey” from Michael Kallfelz, Christian Reich and Patrick Ryan, including both the video and slides from the community call, as well as the introduction from the Vocabulary chapter in the Book of OHDSI, is available here.

• The OMOP CDM Workshop that was held earlier this month has been put together into a single video tutorial, which you can find here. This page also has all the slides from the workshop, as well as the CDM introductory text from the Book of OHDSI.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Reproducibility Challenge | Designing Reproducible Studies | OHDSI Reproducibility Service | Community Updates

Video Presentations

Reproducibility Challenge (Anna Ostropolets)

Designing Reproducible Studies (Martijn Schuemie)

The OHDSI Reproducibility Service (Asieh Golozar)

The March 22 OHDSI Community Call provided an in-depth look at the OHDSI vocabulary, from how it is developed, to how it can be utilized, and where it should grow from here. Three leaders from the vocabulary workgroup joined to present a trio of topics for this session (see below). 

– A peek into the OHDSI vocabulary engine room (Michael Kallfelz)
– Fun things you can learn with the OHDSI standardized vocabularies (Patrick Ryan)
– Time for reflection • Where are we? Where should we be? (Christian Reich)

Community Updates

• Congratulations to the team of JungHyun Byun, Dong Yun Lee, Chang-Won Jeong, Yerim Kim, Hak Young Rhee, Ki Won Moon, Jeongwon Heo, Yoonki Hong, Woo Jin Kim, Seung-Joo Nam, Hoon Sung Choi, Ji In Park, In Kook Chun, So Hyeon Bak, Kyoungyul Lee, Gi Hwan Byeon, Kyoung Lae Kim, Jeong-Ah Kim, Young Joo Park, Jeong Hyun Kim, Eun ju Lee, Sang-Ah Lee, Sung Ok Kwon, Sang-Won Park, Payam Hosseinzadeh Kasani, Jung-Kyeom Kim, Yeshin Kim, Seongheon Kim and Jae-Won Jang on the publication of Analysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer’s dementia using OMOP CDM in Scientific Reports.

• Congratulations to the team of Kristin Kostka, Talita Duarte-Salles, Albert Prats-Uribe, Anthony G Sena, Andrea Pistillo, Sara Khalid, Lana YH Lai, Asieh Golozar, Thamir M Alshammari, Dalia M Dawoud, Fredrik Nyberg, Adam B Wilcox, Alan Andryc, Andrew Williams, Anna Ostropolets, Carlos Areia, Chi Young Jung, Christopher A Harle, Christian G Reich, Clair Blacketer, Daniel R Morales, David A Dorr, Edward Burn, Elena Roel, Eng Hooi Tan, Evan Minty, Frank DeFalco, Gabriel de Maeztu, Gigi Lipori, Hiba Alghoul, Hong Zhu, Jason A Thomas, Jiang Bian, Jimyung Park, Jordi Martínez Roldán, Jose D Posada, Juan M Banda, Juan P Horcajada, Julianna Kohler, Karishma Shah, Karthik Natarajan, Kristine E Lynch, Li Liu, Lisa M Schilling, Martina Recalde, Matthew Spotnitz, Mengchun Gong, Michael E Matheny, Neus Valveny, Nicole G Weiskopf, Nigam Shah, Osaid Alser, Paula Casajust, Rae Woong Park, Robert Schuff, Sarah Seager, Scott L DuVall, Seng Chan You, Seokyoung Song, Sergio Fernández-Bertolín, Stephen Fortin, Tanja Magoc, Thomas Falconer, Vignesh Subbian, Vojtech Huser, Waheed-Ul-Rahman Ahmed, William Carter, Yin Guan, Yankuic Galvan, Xing He, Peter R Rijnbeek, George Hripcsak, Patrick B Ryan, Marc A Suchard, and Daniel Prieto-Alhambra on the publication of Unraveling COVID-19: A Large-Scale Characterization of 4.5 Million COVID-19 Cases Using CHARYBDIS in Clinical Epidemiology.

• We are thrilled to announce that registration for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center, is now open!

The main conference will be held Friday, Oct. 14, while a full-day tutorial will be held Saturday, Oct. 15. Other community activities, mainly focused on OHDSI workgroups, will be held both Oct. 15 and Oct. 16. The OHDSI2022 homepage has more information, as well as registration links to both the conference and the tutorial (these are separate events and each requires its own registration), information on the collaborator showcase, hotel room blocks, and plenty more.

Direct registration is available for both the main conference and the full-day tutorial. Please continue to check our symposium homepage and our social platforms, and join the weekly OHDSI community calls, for more information.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 12 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• The OMOP CDM Workshop that was held over the last two OHDSI Community Calls has been put together into a single video tutorial, which you can find here. This page also has all the slides from the workshop, as well as the CDM introductory text from the Book of OHDSI.

• The next APAC Community Call will be held this Wednesday/Thursday based on your time zone. Christian Reich will present on the OMOP/FHIR collaboration during this call. You can access these calls by joining the Asia-Pacific (APAC) Workgroup in Teams.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

OHDSI Vocabulary Journey | Community Updates

Video Presentation

Clair Blacketer and members of the CDM Workgroup put together the second of a two-part CDM Workshop session during the March 15 OHDSI Community Call. Following an introduction by Clair, there were specific talks on the following topics:

• Vocabulary Mapping and Usagi (Melanie Philofsky)
• Data Quality (Clair Blacketer)
• ACHILLES (Anthony Molinaro)
• Putting It All Together (Frank DeFalco) 

Part 1 of this workshop was held during the March 8 Community Call; you can watch that video here: https://youtu.be/y7CXONEMLoI.

Community Updates

• Congratulations to the team of Matthew Spotnitz, Anna Ostropolets, Victor G. Castanob, Karthik Natarajan, Genna Waldman, Michael Argenziano, Ruth Ottman, George Hripcsak, Hyunmi Choi, and Brett Youngerman for the publication of Patient characteristics and antiseizure medication pathways in newly diagnosed epilepsy: Feasibility and pilot results using the common data model in a single-center electronic medical record database recently in Epilepsy & Behavior.

• The 2022 OHDSI Symposium will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center in Bethesda, Md. The main symposium will be held Friday, Oct. 14, while the next two weekend will include community activities. More information about the weekend, including registration and the collaborator showcase, will be shared when available.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 12 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Phenotype Phebruary may have ended, but the conversations still continue in the OHDSI forums. All of the “phun phacts” that were shared during our community calls have been put together in a single video, so you can learn about all 29 phenotypes discussed during the month. All daily threads can be found on the Phenotype Phebruary homepage.

• Our colleagues within EHDEN are opening their fourth and final call for SMEs to apply for training and certification on converting health data from various formats to the OMOP common data model. Currently, EHDEN has 47 SMEs across 19 European nations working on the EHDEN data network, which includes 140 data partners across 16 countries. You can see the fill list of EHDEN-certified SMEs, as well the EHDEN data partner network.

• Dani Prieto-Alhambra recently shared that his team at Oxford is accepting applications for an IT System Manager and Database Administrator. The deadline for application is April 11, 2022. For more registration and to apply, please visit the Job Details page.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

CDM Workshop | Community Updates

Video

CDM Workshop (Clair Blacketer, Melanie Philofsky, Anthony Molinaro and Frank DeFalco)

The March 8 OHDSI community call featured Part 1 of our two-week OMOP CDM Workshop. We were excited to have four representatives from our Common Data Model Workgroup lead this session:  

• Clair Blacketer, Associate Director, Janssen Research & Development
• Frank DeFalco, Director, Observational Health Data Analytics, Janssen Research & Development
• Kristin Kostka, Director of the OHDSI Center, Roux Institute, Northeastern University
• Maxim Moinat, Data Engineer/Software Developer, The Hyve

Prior to the CDM Workshop, Paul Nagy presented the newly developed Engine of Impact Project (EOI), a dashboard that allows for regular monitoring of the health and progress of the OHDSI community. Videos/slides for both the CDM Workshop and EOI Project are below.

Community Updates

• The 2022 OHDSI Symposium will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center in Bethesda, Md. The main symposium will be held Friday, Oct. 14, while the next two weekend will include community activities. More information about the weekend, including registration and the collaborator showcase, will be shared when available.

• The latest edition of The Journey newsletter is now available. This edition includes a full review of Phenotype Phebruary, a look at the DARWIN EU announcement by the European Medicines Agency, publications and presentations, and much more. If you don’t get The Journey in your email, please subscribe here.

• 2021 OHDSI Titan Award winner Maxim Moinat was profiled in our latest Collaborator Spotlight. Learn more about Maxim’s background, his work with open-source tools, EHDEN, the upcoming DARWIN EU initiative, and much more.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• If you missed Nicole Pratt’s CBER BEST Seminar on “Evaluating Use of Methods for Adverse Event Under Surveillance for Vaccines,” you can watch it now.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

CDM Workshop | EOI Project | Community Updates

Videos

CDM Workshop (Clair Blacketer, Frank DeFalco, Kristin Kostka, Maxim Moinat)

Engine of Impact Project (Paul Nagy)

The March 1 OHDSI community call included final reflections on Phenotype Phebruary, and then hosted breakout discussions on what is happening around the three main OHDSI focuses of characterization, estimation and prediction, and how do we as a community collaborate to accomplish our 2022 OKRs. 

• Patrick Ryan will led the final update on Phenotype Phebruary, which you can join in the daily conversations at the OHDSI forums or at the event homepage
• Anthony Sena and Aniek Markus moderated a conversation in work around Characterization
• Marc Suchard moderated a conversation in work around Estimation
• Jenna Reps and Ross Williams moderated a conversation in work around Prediction

Community Updates

• As announced at our last community call, the 2022 OHDSI U.S. Symposium will be held Oct. 14-16, with the main symposium set for Oct. 14. We will have more information on the event in the coming weeks, but please save those dates for #OHDSI2022.

• Phenotype Phebruary completed its final week, and it has been amazing to watch the activity ongoing on so many threads discussing different phenotypes developments & evaluation. Each daily post is linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Asieh Golozar, Rupa Makadia, Jill Hardin, Erica Voss, Tiffany Callahan, Juan Banda, Anna Ostropolets, Claudia Pulgarin, Marcela Rivera, and David Vizcaya for leading these discussions

Feb. 21 • Prostate Cancer
Feb. 22 • HIV
Feb. 23 • Hidradenitis Suppurativa
Feb. 24 • Anaphylaxis
Feb. 25 • Depression
Feb. 26 • Non-Small-Cell Lung Cancer
Feb. 27 • Drug-Induced Liver Injury
Feb. 28 • Severe Visual Impairment and Blindness
Bonus • Acute Kidney Injury

• Congratulations to the team of Edward Burn, Xintong Li, Kristin Kostka, Henry Morgan Stewart, Christian Reich, Sarah Seager, Talita Duarte-Salles, Sergio Fernandez-Bertolin, María Aragón, Carlen Reyes, Eugenia Martinez-Hernandez, Edelmira Marti, Antonella Delmestri, Katia Verhamme, Peter Rijnbeek, Scott Horban, Daniel Morales, and Daniel Prieto-Alhambra on the recent publication of Background rates of five thrombosis with thrombocytopenia syndromes of special interest for COVID-19 vaccine safety surveillance: Incidence between 2017 and 2019 and patient profiles from 38.6 million people in six European countries in Pharmacoepidemiology and Drug Safety.

• Congratulations to the team of Emily Pfaff, Melissa Haendel, Kristin Kostka, Adam Lee, Emily Niehaus, Matvey Palchuk, Kellie Walters, and Christopher Chute on the recent publication of Ensuring a safe(r) harbor: Excising personally identifiable information from structured electronic health record data in the Journal of Clinical and Translational Science.

• Clair Blacketer led Part 2 of a CDM Workshop for the Asia-Pacific (APAC) community as part of the most recent APAC Community Call (see video here). Clair will lead a two-part workshop on the global community call over the next two weeks.

• Curious about the Objectives & Key Results (OKRs) set by our various workgroups. These were presented at a recent meeting between workgroup leads, and they have been posted to the new OHDSI Workgroups page. If you want to join any of our workgroups, please fill out this form.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase wraps up this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: OMOP-CDM ETLs with Dask and Prefect
Tuesday: Learning under constraints with EXPLORE
Wednesday: Estimating Model Performance on External Datasets from Their Limited Statistical Characteristics: Application to 3-Year Surgery Risk in Ulcerative Colitis

Slides

Phenotype Phebruary Report | Prediction Breakout | Community Updates

Videos

Phenotype Phebruary Final Report (Patrick Ryan)

Characterization Discussion (moderated by Aniek Markus and Anthony Sena)

Estimation Discussion (moderated by Marc Suchard)

Prediction Discussion (moderated by Jenna Reps and Ross Williams)

The Feb. 22 OHDSI community call featured a trio of presentations:

Community Updates

• Phenotype Phebruary is heading into the final week, and we currently have 20 interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Azza Shoaibi, Gowtham Rao, Adam Black and Evan Minty for leading these discussions

Feb. 14 • Hypertension (Video Description)
Feb. 15 • Acute Myocardial Infarction
Feb. 16 • Heart Failure
Feb. 17 • Cardiomyopathy
Feb. 18 • Multiple Sclerosis
Feb. 19 • Triple Negative Breast Cancer
Feb. 20 • Pulmonary Hypertension
Feb. 21 • Prostate Cancer

• The next CBER Best Seminar will be provided by a veteran collaborator within the OHDSI community. Nicole Pratt (Professor, University of South Australia) will present on “Evaluating Use of Methods for Adverse Event Under Surveillance For Vaccines” at 11 am ET this Wednesday, Feb. 23. This seminar is free and open to the public; you can register here.

• The next Asia-Pacific (APAC) Community Call will be held Wednesday, March 23 at 10 pm ET. Clair Blacketer will provide part 2 of the first CDM Workshop of 2022. If you missed the first part, you can watch that recording here.

• Curious about the Objectives & Key Results (OKRs) set by our various workgroups? These were presented at a recent meeting between workgroup leads, and they have been posted to the new OHDSI Workgroups page. If you want to join any of our workgroups, please fill out this form.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage. 

• Our collaborators at Janssen Research & Development recently posted a new position for Manager, Observational Health Data Analytics. You can find a job description and application link here.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Attention based deep neural networks in patient level prediction
Tuesday: REDCap2OMOP: A platform for ETLing REDCap projects into the OMOP CDM
Wednesday: Trends in the development and validation of patient-level prediction models using electronic health record data: a systematic review
Thursday: Short-term mortality in patients undergoing colorectal cancer surgery: A prediction study
Friday: Proof-of-concept model targeting patient-level prediction of 90-day mortality after colorectal cancer surgery kickstarts OHDSI journey

Slides

ATLAS WG | Medical Imaging WG | Phenotype Phebruary | Community Updates

Video Presentations

ATLAS WG (Anthony Sena)

Medical Imaging WG (Paul Nagy)

Phenotype Phebruary (Patrick Ryan)

The Feb. 8 OHDSI community call featured a trio of presentations:

Community Updates

• Congratulations to Peter Rijnbeek and all of our collaborators at the Erasmus University Medical Center for being awarded a contract to establish the Coordination Center for the Data Analysis and Real World Interrogation Network (DARWIN EU). As noted in this EHDEN press release, “DARWIN EU will be able to leverage the extensive work done within the European Health Data and Evidence Network (EHDEN) project funded by the Innovative Medicines Initiative (IMI), and the Observational Health Data Sciences and Informatics (OHDSI) community.”

• Phenotype Phebruary has begun, and we have six interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Azza Shoaibi, Gowtham Rao, Joel Swerdel, Allan Wu and Patrick Ryan for leading these discussions.

Feb 7 • Neutropenia
Feb 8 • Kidney Stones
Feb 9 • Delirium
Feb 10 • Systemic Lupus Erythematosus
Feb 11 • Suicide Attempts
Feb 12 • Parkinson’s Disease and Parkinsonism
Feb 13 • Attention Deficit Hyperactivity Disorder
Feb 14 • Hypertension

• The next CBER Best Seminar will be provided by a veteran collaborator within the OHDSI community. Nicole Pratt (Professor, University of South Australia) will present on “Evaluating Use of Methods for Adverse Event Under Surveillance For Vaccines” at 11 am ET on Wednesday, Feb. 23. This seminar is free and open to the public; you can register here. 

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Scaling OHDSI open-source community projects, lessons learned by Oncology Work group
Tuesday: CemConnector: A RESTFul application programing interface and client library for the Common Evidence Model (CEM)
Wednesday: Disease Progression Modeling Workbench 360
Thursday: Evaluating Patient Count Vs Hospitalization Risk for Common Clinical Trial Eligibility Criteria: A Case Study for Relapsed/Refractory Lymphoma/Leukemia
Friday: Representation of investigational drugs in the OMOP CDM

Slides

CDM Workgroup | Data Quality Workgroup | Phenotype Phebruary Report | Community Updates

Video Presentations

CDM Workgroup Update (Clair Blacketer)

Data Quality Workgroup Update (Clair Blacketer)

Phenotype Phebruary Report #2 (Patrick Ryan)

The Feb. 8 OHDSI community call featured a trio of presentations:

Community Updates

• Phenotype Phebruary has begun, and we have six interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations.

Feb. 1 • Type 2 Diabetes Mellitus
Feb. 2 • Type 1 Diabetes Mellitus
Feb. 3 • Atrial Fibrillation
Feb. 4 • Multiple Myeloma
Feb. 5 • Alzheimer’s Disease
Feb. 6 • Hemorrhagic Events
Feb. 7 • Neutropenia

• The February 2022 edition of The Journey newsletter is now available. If you don’t the newsletter in your email, please subscribe here. What will you find in the latest edition of The Journey?

• Community Updates
• Extracting OHDSI Concepts from Clinical Narratives for COVID Presentation
• OHDSI Goals for 2022
• Recent Publications
• MORE! 

• Longtime OHDSI collaborator Jon Duke will lead a discussion on saying goodbye to manual registries with the creation of interoperable EHR based clinical registries during the next Grand Rounds at Johns Hopkins, led by Paul Nagy. This leverages the forefront of the OHDSI and FHIR communities committed to open standards and open science. This free session takes place Thursday at 12 pm ET, and you can register here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Diagnostic Accuracy of Code-Based Algorithms to Identify Urinary Tract Infection in U.S. Administrative Claims Databases
Tuesday: Assessing impact on change in incidence on calibration performance across external validation
Wednesday: A journey through VA’s uptake of the OMOP common data model
Thursday: Medication dosage and exposure duration in OMOP CDM: mapping challenges
Friday: There & Back Again: Using Julia to Augment OHDSI R Packages

Slides

Healthcare Systems | Open Source Community | Phenotype Phebruary | Community Updates

Video Presentations

Healthcare Systems Special Interest Group Update (Melanie Philofsky)

Open Source Community Workgroup Introduction Announcement (Adam Black)

Phenotype Phebruary Report #1 (Patrick Ryan)

Patrick Ryan introduced a community-wide activity around developing and evaluating at least 28 phenotypes across the 28 days of February. This presentation includes a discussion on the importance of phenotypes, a closer look at OHDSI tools that can be used in developing and evaluating them, a plan for executing this initiative across the community, and a jump into the Day 1 phenotype: Type 2 Diabetes Mellitus.

Community Updates

• Congratulations to the team of Ross D. Williams, Aniek F. Markus, Cynthia Yang, Talita Duarte-Salles, Scott L. DuVall, Thomas Falconer, Jitendra Jonnagaddala, Chungsoo Kim, Yeunsook Rho, Andrew E. Williams, Amanda Alberga Machado, Min Ho An, María Aragón, Carlos Areia, Edward Burn, Young Hwa Choi, Iannis Drakos, Maria Tereza Fernandes Abrahão, Sergio Fernández-Bertolín, George Hripcsak, Benjamin Skov Kaas-Hansen, Prasanna L. Kandukuri, Jan A. Kors, Kristin Kostka, Siaw-Teng Liaw, Kristine E. Lynch, Gerardo Machnicki, Michael E. Matheny, Daniel Morales, Fredrik Nyberg, Rae Woong Park, Albert Prats-Uribe, Nicole Pratt, Gowtham Rao, Christian G. Reich, Marcela Rivera, Tom Seinen, Azza Shoaibi, Matthew E. Spotnitz, Ewout W. Steyerberg, Marc A. Suchard, Seng Chan You, Lin Zhang, Lili Zhou, Patrick B. Ryan, Daniel Prieto-Alhambra, Jenna M. Reps and Peter R. Rijnbeek on the publication of “Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network” in BMC Medical Research Methodology.

• Congratulations to the team of Seung-Hwa Lee, Jungchan Park, Rae Woong Park, Seo Jeong Shin, Jinseob Kim, Ji Dong Sung, Dae Jung Kim, and Kwangmo Yang on the publication of “Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Cancer: A Population-Based Cohort Study Using a Common Data Model” in Diagnostics. 

• The most recent Asia-Pacific (APAC) Community Call was held last week, and it featured a CDM Workshop led by Clair Blacketer. This was the first of several planned CDM Workshops for 2022, and video of this session is now available. You can also find a written Q&A from the workshop on our APAC Community page.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Securing OHDSI on AWS for HIPAA and Research Data Management Compliance
Tuesday: Identification of treatment intent from the actual time-to-treatment distribution in prostate cancer patients
Wednesday: The concept of anchoring in observational study design and its influence
Thursday: Summarizing current evidence for the PIONEER study-a-thon: Systematic Literature Review of prostate cancer patients managed with watchful waiting
Friday: LAISDAR – A federated data network to support COVID-19 research in Rwanda

Slides

Presentation | Community Updates

Video

During our Jan. 18 community call, Dr. Hongfang Liu (Mayo Clinic) and Dr. Christopher Chute (Johns Hopkins University) led a session on Extracting OHDSI Concepts from Clinical Narratives for COVID. Following the presentation (approximately 33 minutes), there is a Q&A session. 

Community Updates

• Congratulations to co-authors ChulHyoung Park, Seng Chan You, Hokyun Jeon, Chang Won Jeong, Jin Wook Choi, and Rae Woong Park on the publication of “Development and Validation of the Radiology Common Data Model (R-CDM) for the International Standardization of Medical Imaging Data” which was recently published in the Yonsei Medical Journal.

• Congratulations to co-authors Xiangmin Ji, Guimei Cui, Chengzhen Xu, Jie Hou, Yunfei Zhang, and Yan Ren on the publication of “Combining a Pharmacological Network Model with a Bayesian Signal Detection Algorithm to Improve the Detection of Adverse Drug Events” recently in Frontiers in Pharmacology.

• Congratulations to the team of Seung-Hwa Lee, Jungchan Park, Rae Woong Park, Seo Jeong Shin, Jinseob Kim, Ji Dong Sung, Dae Jung Kim, and Kwangmo Yang on the publication of “Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Cancer: A Population-Based Cohort Study Using a Common Data Model” in Diagnostics.

• Our friends in the EHDEN Project recently highlighted its many successes over the first three years of its five-year project, including harmonizing more than 500 million health records across 27 countries, developing 14 courses (and counting) in the EHDEN Academy, and plenty more. You can read that report here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• Our Janssen collaborators recently announced an opening for two summer interns for its 2022 Observational Health Data Analytics Internship Program. Learn more about this opportunity and apply using that link.

• The #OHDSISocialShowcase continues on Wednesday this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: The VISIT_DETAIL: A Vehicle for Standard Visits
Tuesday: Leveraging APHRODITE to identify bias in statistical phenotyping algorithms
Wednesday: From type 2 diabetes diagnosis to developing complications: a multi-country approach to understanding patients journey
Thursday: Distributed Counterfactual Modeling Approach for Investigating Hospital-Associated Racial Disparities in COVID-19 Mortality
Friday: Design of a framework to detect temporal clinical event trajectories from health data standardized to the OMOP CDM

Slides

Presentation | Community Updates

Video

During our Jan. 18 community call, workgroups came together in GatherTown to discuss Objectives and Key Results (OKRs) to set for 2022. These OKRs will be evaluated quarterly at both the global community level, as well as within the individual workgroups, to measure the success our community is having, and where we need to put greater attention moving forward.

That session was not recorded; it followed our weekly community updates, which are available below.

Community Updates

• Congratulations to co-authors Daniel Morales, Anna Ostropolets, Lana Lai, Anthony Sena, Scott Duvall, Marc Suchard, Katia Verhamme,Peter Rjinbeek, Jose Posada, Waheed Ahmed, Thamer Alshammary, Heba Alghoul, Osaid Alser, Carlos Areia, Clair Blacketer, Ed Burn, Paula Casajust, Seng You, Dalia Dawoud, Asieh Golozar, Menchung Gong, Jitendra Jonnagaddala, Kristine Lynch, Michael Matheny, Evan Minty, Fredrik Nyberg, Albert Uribe, Martina Recalde, Christian Reich, Martijn Scheumie, Karishma Shah, Nigam Shah, Lisa Schilling, David Vizcaya, Lin Zhang, George Hripcsak, Patrick Ryan, Daniel Prieto-Alhambra, Talita Durate-Salles, and Kristin Kostka on the publication of “Characteristics and outcomes of COVID-19 patients with and without asthma from the United States, South Korea, and Europe” which was recently published in the Journal of Asthma.

• Congratulations to Seng Chan You and Harlan Krumholz, who recently published this commentary in Circulation: The Evolution of Evidence-Based Medicine: When the Magic of the Randomized Clinical Trial Meets Real-World Data.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The latest edition of “The Journey” OHDSI newsletter is now available, and it looked back at 12 highlights from the OHDSI community in 2021. If you aren’t receiving this newsletter each month, you can subscribe here. 

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Wednesday: REDHot OMOP: Facilitating Semantic Interoperability in REDCap with FHIR and the OMOP CDM
Thursday: Imputation of Continuous Measurements in Large Healthcare Databases: Comparing the Performance of Imputation Algorithms
Friday: An EUMAEUS investigation: how much can be gained in vaccine safety surveillance by including second dose data?

Patrick Ryan led the first OHDSI Community Call of 2022 with a presentation about what OHDSI can accomplish together this year. While the community listed and voted upon several objectives, Patrick discussed his hope to develop a system to generate evidence that characterizes disease and treatment utilization, estimates the effects of medical interventions, and predicts outcomes of patients within a network of observational health databases.

Other aspects of the discussion included a look at OHDSI workgroups and how they can continue moving forward, 2021 achievements, and more. Both video of the presentation and Patrick’s slides are available below.

Community Updates

• Congratulations to co-authors Nicolas Paris, Antoine Lamer and Adrien Parrot on the study “Transformation and Evaluation of the MIMIC Database in the OMOP Common Data Model: Development and Usability Study” which was published in JMIR Medical Informatics on Dec. 14.

• Congratulations to co-authors Sooin Choi, Soo Jeong Choi, Jin Kuk Kim, Ki Chang Nam, Suehyun Lee, Ju Han Kim and You Kyoung Lee on the study “Preliminary feasibility assessment of CDM-based active surveillance using current status of medical device data in medical records and OMOP-CDM” which was published in Scientific Reports on Dec. 15.

• Congratulations to co-authors Anastasiya Nestsiarovich, Jenna Reps, Michael Matheny, Scott DuVall, Kristine Lynch, Maura Beaton, Xinzhuo Jiang, Matthew Spotnitz, Stephen Pfohl, Nigam Shah, Carmen Olga Torre, Christian Reich, Dong Yun Lee, Sang Joon Son, Seng Chan You, Rae Woong Park, Patrick Ryan & Christophe Lambert on the study “Predictors of diagnostic transition from major depressive disorder to bipolar disorder: a retrospective observational network study” which was published in Translational Psychiatry on Dec. 20.

• Congratulations to co-authors Carlen Reyes, Andrea Pistillo, Sergio Fernández-Bertolín, Martina Recalde, Elena Roel, Diana Puente, Anthony Sena, Clair Blacketer, Lana Lai, Thamir Alshammari, Waheed-UI-Rahman Ahmed, Osaid Alser, Heba Alghoul, Carlos Areia, Dalia Dawoud, Albert Prats-Uribe, Neus Valveny, Gabriel de Maeztu, Luisa Sorlí Redó, Jordi Martinez Roldan, Inmaculada Lopez Montesinos, Lisa M Schilling, Asieh Golozar, Christian Reich, Jose Posada, Nigam Shah, Seng Chan You, Kristine Lynch, Scott DuVall, Michael Matheny, Fredrik Nyberg, Anna Ostropolets, George Hripcsak, Peter Rijnbeek, Marc Suchard, Patrick Ryan, Kristin Kostka, and Talita Duarte-Salles on the study “Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study” which was published in BMJ Open on Dec. 22.

• Congratulations to co-authors Jenna Reps, Patrick Ryan, and Peter Rijnbeek on the study “Investigating the impact of development and internal validation design when training prognostic models using a retrospective cohort in big US observational healthcare data” which was published in BMJ Open on Dec. 24.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The latest edition of “The Journey” OHDSI newsletter is now available, and it looked back at 12 highlights from the OHDSI community in 2021. If you aren’t receiving this newsletter each month, you can subscribe here.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: CohortIncidence: A Standardized Framework for Characterizing Incidence Using OMOP Common Data Model and OHDSI tools
Tuesday: Beyond Clinical: Integrating Research Assay Data into the Observational Health Data Sciences and Informatics Common Data Model (OHDSI CDM) through the Surgical Critical Care Initiative (SC2i)
Wednesday: Comparing Data Quality Dashboard results from consecutive ETL iterations: three new utilities
Thursday: Empirical Assessment of Alternative Methods for Identifying Seasonality in Observational Healthcare Data
Friday: ATLAS with a BigQuery backend running Execution Engine – a Software demo

OPENINGS

• Janssen R&D recently posted an “Associate Director, Observational Health Data Analytics” position in its world-class epidemiology department.

• The Bouvé College of Health Sciences and The Roux Institute at Northeastern University seek candidates for two full-time tenure-track Assistant Professor positions in the emerging area of health/healthcare data science. The successful candidate will have primary responsibility for working with the OHDSI Center at the Roux Institute, focusing on education, research and community support of the global Open Source OHDSI initiative. For more information, please reach out to Brianne Olivieri-Mui, Assistant Professor, Department of Health Sciences, at B.mui@northeastern.edu. 

Slides

Main Presentation (Ryan) | Community Updates

Video