OHDSI Community Calls

Everybody is invited to the weekly OHDSI community call, which takes place each Tuesday at 11 am ET. These calls are meant to inform and engage our community through a variety of call formats, including community presentations, workgroup updates, breakout sessions, publication announcements, newcomer-focused sessions, and more. The upcoming schedule is available to the right.  

Videos, slides and weekly updates from this year’s calls are available below. Presentations from the 20232022 and 2021 community calls are also available. 

Weekly Recordings & Updates

Each community call during “Phenotype Phebruary” features a set of Workgroup 2024 Objectives & Key Result (OKR) announcements, as well an update from that week’s Phenotype Phebruary activities and findings. Workgroups that presented during this call were Themis, Healthcare Systems, Generative AI and Foundational Models, Oncology, Vaccine Vocabulary, Patient-Level Prediction (PLP), ATLAS, Open-Source Community, Psychiatry, and Natural Language Processing (NLP). The Phenotype Phebruary update, led by Anna Ostropolets and Jamie Weaver, reflected on findings from the first two weeks, as well as early research and critical questions around the Week 3 phenotype, major depressive disorder. 

Community Updates

• Congratulations to the team of Martin Boeker, Daniela Zöller, Romina Blasini, Philipp Macho, Sven Helfer, Max Behrens, Hans-Ulrich Prokosch and Christian Gulden on the publication of Effectiveness of IT-supported patient recruitment: study protocol for an interrupted time series study at ten German university hospitals in Trials

• Congratulations to the team of Moshe Zisser and Dvir Aran on the publication of Transformer-based time-to-event prediction for chronic kidney disease deterioration in JAMIA.

• The 2024 OHDSI Global Symposium will be held Oct. 22-24 at the Hyatt Regency Hotel in New Brunswick, NJ. The tentative symposium format will feature tutorials and workshops on Oct. 22, the main conference on Oct. 23, and workgroup activities on Oct. 24. Registration has not opened yet.

• Registration is now OPEN for the 2024 OHDSI Europe Symposium, which will be held June 1-3 in Rotterdam, Netherlands. There will be tutorials and workshops June 1-2 at the Erasmus University Medical Center, and the main conference will be held Monday, June 3, on the Steam Ship Rotterdam. Please visit the event homepage for more information and registration details.

• Henrik John recently announced a new network study that he is leading with Chungsoo Kim, Jenna Reps and Egill Fridgeirsson on “Deep Learning Comparison.” The aim is to assess the value of deep learning methods over conventional methods for the development of clinical prediction models. The specific diseases under consideration are dementia in individuals over 55, lung cancer in those over 45, and bipolar disorder in patients misdiagnosed with major depressive disorder. If you would like to join this effort, please read this forum post for more information and reach out to the study leads by March 1.

• James Weaver, an Associate Director of Observational Health Data Analytics at Janssen Research and Development, will speak during a panel session on Current Approaches for Distributed Analysis on Thursday, March 14 (1 pm ET) during a Health Data Research Network Canada event. This will be a virtual conversation; more information and a registration link are available here.

• Under the leadership of Azza Shoaibi, Anna Ostropolets, Gowtham Rao and James Weaver, Phenotype Phebruary 2024 focuses on assessing consistency in phenotype definition components, phenotype representation structure, and phenotype validation methods. The month-long activity empowers OHDSI collaborators to engage with each other while advancing the science of phenotyping and gaining education and training around phenotype development and evaluation. You can check out the event homepage here.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Challenges and opportunities in adopting OMOP-CDM in Brazilian healthcare: a report from Hospital Israelita Albert Einstein (Maria Abrahao)
Tuesday — Developing a pregnancy algorithm in ATLAS: Applying start date offset (Rupa Makadia)
Wednesday — Creating parsimonious patient-level prediction models using feature selection (Aniek Markus)
Thursday — From Complexity to Clarity: Reproducible and Scalable Phenotype Development and application of LLM in a support role (Asieh Golozar)
Friday — Establishing and Operating the OHDSI Dentistry Workgroup: A Model for Other Disciplines (Danielle Boyce)

Job Openings

• Alex Asiimwe shared three openings at Gilead that could be of interest to OHDSI collaborators. There are openings for a Director, RWE – Data Science, a Director, Data Acquisition, and a Senior Director, Head of Data Office. You can learn more about each position and apply using the links above.

• Linying Zhang shared openings for both a Postdoc and a Senior Data Analyst at the Washington University School of Medicine in St. Louis. Successful candidates will work on causal machine learning and responsible AI for reliable real-world evidence generation. Interested applicants should send a CV and cover letter to linyingz@wustl.edu.

• Nathan Hall introduced a summer internship at Johnson & Johnson for an Epidemiology UX/Web Design Intern. This internship provides a unique opportunity to merge design principles with epidemiological research, contributing to the advancement of real-world evidence applications. In this role, you will have the opportunity to blend your passion for user experience (UX) and web design with the field of epidemiology, contributing to impactful projects that enhance our ability to derive insights from health data. More information and an application link are available here.

• There is an opening for an Epidemiology Graduate Intern at Johnson & Johnson. Among the responsibilities for this remote position are assisting in managing epidemiologic studies and literature reviews to characterize incidence, prevalence, risk factors, and associated comorbidities and treatment patterns for lung, head, and neck cancers across interventional oncology, contributing to the development of protocols for analyzing real-world data cohorts, such as SEER Medicare, and conducting quantitative analyses using both public and private data sources. More information and an application link are available here.

The University of North Carolina Chapel Hill CTSA is hiring a Research Informatics Specialist. This is a remote position (US only, with mostly East Coast hours). This person will join a skilled and highly collaborative team of data analysts, software developers, and data scientists within our CTSA. The core purpose of this position is to support the All of Us Center for Linkage and Acquisition of Data project. We are looking for folks with SQL and health care and/or claims data experience, especially OMOP.

There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM.

Slides

Phenotype PhebruaryWorkgroup OKRs + Community Updates

Videos

Workgroup Updates (Themis, Healthcare Systems, Generative AI and Analytics in Healthcare (GAIA), Oncology, Vaccine Vocabulary, Patient-Level Prediction, ATLAS, Open Source Community, Psychiatry, and NLP)

Phenotype Phebruary Update #3

Each community call during “Phenotype Phebruary” features a set of Workgroup 2024 Objectives & Key Result (OKR) announcements, as well an update from that week’s Phenotype Phebruary activities and findings. Workgroups that presented during this call were Common Data Model, Network Data Quality, Asia-Pacific (APAC), Industry, Eye Care & Vision Research, and Surgery & Perioperative Medicine. The Phenotype Phebruary update focused on the findings from the Week 1 phenotype, Alzheimer’s Disease, as well as early research and critical questions around the Week 2 phenotype, non-small cell and small cell lung cancer.

Community Updates

• Congratulations to the team of Xinyuan Zhang, Yixue Feng, Fang Li, Jin Ding, Danyal Tahseen, Ezekiel Hinojosa, Yong Chen, and Cui Tao on the publication of Evaluating MedDRA-to-ICD terminology mappings in BMC Medical Informatics and Decision Making

• Congratulations to the team of Tathagata Bhattacharjee, Sylvia Kiwuwa-Muyingo, Chifundo Kanjala, Molulaqhooa L Maoyi, David Amadi, Michael Ochola, Damazo Kadengye, Arofan Gregory, Agnes Kiragga, Amelia Taylor, Jay Greenfield, Emma Slaymaker, Jim Todd, and the INSPIRE Network on the publication of INSPIRE datahub: a pan-African integrated suite of services for harmonising longitudinal population health data using OHDSI tools in Frontiers in Digital Health.

• Registration is now OPEN for the 2024 OHDSI Europe Symposium, which will be held June 1-3 in Rotterdam, Netherlands. There will be tutorials and workshops June 1-2 at the Erasmus University Medical Center, and the main conference will be held Monday, June 3, on the Steam Ship Rotterdam. Please visit the event homepage for more information and registration details.

• If you are interested in joining the Scientific Review Committee for the 2024 Global Symposium, you can sign up now. The first meeting for the Scientific Review Committee will be held March 7.

• Henrik John recently announced a new network study that he is leading with Chungsoo Kim, Jenna Reps and Egill Fridgeirsson on “Deep Learning Comparison.” The aim is to assess the value of deep learning methods over conventional methods for the development of clinical prediction models. The specific diseases under consideration are dementia in individuals over 55, lung cancer in those over 45, and bipolar disorder in patients misdiagnosed with major depressive disorder. If you would like to join this effort, please read this forum post for more information and reach out to the study leads by March 1.

• James Weaver, an Associate Director of Observational Health Data Analytics at Janssen Research and Development, will speak during a panel session on Current Approaches for Distributed Analysis on Thursday, March 14 (1 pm ET) during a Health Data Research Network Canada event. This will be a virtual conversation; more information and a registration link are available here.

• Under the leadership of Azza Shoaibi, Anna Ostropolets, Gowtham Rao and James Weaver, Phenotype Phebruary 2024 focuses on assessing consistency in phenotype definition components, phenotype representation structure, and phenotype validation methods. The month-long activity empowers OHDSI collaborators to engage with each other while advancing the science of phenotyping and gaining education and training around phenotype development and evaluation. You can check out the event homepage here.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Toward a General-Purpose Geography-Focused OHDSI Infrastructure (Kyle Zollo-Venecek)
Tuesday — The Development and Validation of an Individual-Level Socioeconomic Deprivation Index (ISDI) with OMOP in the NIH’s All of Us Data Network (Nripendra Acharya)
Wednesday — Incorporating measurement values into patient-level prediction with missing entries: a feasibility study (Xiaoyu Wang)
Thursday — The Use of the Julia Programming Language for Global Health Informatics and Observational Health Research (Jacob Zelko)
Friday — Analyzing a Tabloid Headline with Real-World Data: A Summer Intern’s Investigation (Delia Harms)

Job Openings

• Alex Asiimwe shared three openings at Gilead that could be of interest to OHDSI collaborators. There are openings for a Director, RWE – Data Science, a Director, Data Acquisition, and a Senior Director, Head of Data Office. You can learn more about each position and apply using the links above.

• Linying Zhang shared openings for both a Postdoc and a Senior Data Analyst at the Washington University School of Medicine in St. Louis. Successful candidates will work on causal machine learning and responsible AI for reliable real-world evidence generation. Interested applicants should send a CV and cover letter to linyingz@wustl.edu.

• Nathan Hall introduced a summer internship at Johnson & Johnson for an Epidemiology UX/Web Design Intern. This internship provides a unique opportunity to merge design principles with epidemiological research, contributing to the advancement of real-world evidence applications. In this role, you will have the opportunity to blend your passion for user experience (UX) and web design with the field of epidemiology, contributing to impactful projects that enhance our ability to derive insights from health data. More information and an application link are available here.

The University of North Carolina Chapel Hill CTSA is hiring a Research Informatics Specialist. This is a remote position (US only, with mostly East Coast hours). This person will join a skilled and highly collaborative team of data analysts, software developers, and data scientists within our CTSA. The core purpose of this position is to support the All of Us Center for Linkage and Acquisition of Data project. We are looking for folks with SQL and health care and/or claims data experience, especially OMOP. 

There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM.

Slides

Phenotype Phebruary Update | Workgroup OKRs + Community Updates

Videos

Workgroup Updates (Common Data Model, Network Data Quality, Asia-Pacific (APAC), Industry, Eye Care & Vision Research, and Surgery & Perioperative Medicine)

Phenotype Phebruary Update #2

Each community call during “Phenotype Phebruary” features a set of Workgroup 2024 Objectives & Key Result (OKR) announcements, as well an update from that week’s Phenotype Phebruary activities and findings; the Week 1 phenotype focus was Alzheimer’s Disease. Workgroups that presented during this call were Methods Research, HADES, Perinatal and Reproductive Health, Registry, and the Steering Group.

Community Updates

• If you are interested in joining the Scientific Review Committee for the 2024 Global Symposium, you can sign up now. The first meeting for the Scientific Review Committee will be held March 7.

• Collaborators from both the Columbia University Department of Biomedical Informatics and the Johnson & Johnson Observational Health Data Analytics held a three-day studyathon this past weekend with a focus on women’s health initiatives, specifically endometriosis and polycystic ovary syndrome.

• Kerry Goetz is the Associate Director for the National Eye Institute’s Office of Data Science and Health Informatics at the US National Institutes of Health. In this capacity she is responsible for advancing data management and sharing strategies to make NEI data FAIR (Fully AI-Ready & Findable, Accessible, Interoperable, and Reusable). Kerry co-leads the Eye Care and Vision Research Observational Health Data Sciences and Informatics Working Group. She discusses her career journey, evidence gaps around vision research, how OHDSI impacts her PhD journey, and more in the latest collaborator spotlight.

The latest edition of The Journey newsletter is now available. It includes details on Phenotype Phebruary, reflections on where OHDSI can go together in 2024, the latest OHDSI videocast, and more community updates. It also includes links to 17 published studies that came out of the OHDSI community in January. If you don’t receive the monthly newsletter in your email, you can subscribe here.

• February community calls will focus on both Phenotype Phebruary updates and 2024 OKR announcements by our various workgroups. All workgroup leads/representatives should sign up for one of the upcoming community calls using this link.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — FinOMOP – a population-based data network (Javier Gracia-Tabuenca)
Tuesday — Operational Definition of Adrenal diseases: Enhancing Precision and Reproducibility in Observational Data (Suhyun Kim)
Wednesday — Impact of concomitant use of proton pump inhibitors and clopidogrel on cardiovascular adverse outcomes – A multicenter study using common data model (Seonji Kim)
Thursday — Leveraging the OMOP Common Data Model to Support Distributed Health Equity Research (Sarah Gasman)
Friday — Validating a clinical informatics consulting service using negative control reference sets (Michael Jackson)

HADES Development Updates

• Martijn Schuemie announced the release of CohortMethod 5.2.1. The most important changes are updating the Capr function calls in the vignettes (the old code was no longer working), and CohortMethod now asks if you want to delete old files when you call runCmAnalyses() using an existing folder but different analysis settings than before.

• Ger Inberg announced the release of FeatureExtraction 3.4.0. It contains mainly bugfixes and furthermore the ‘cohortId’ argument in exported functions has been deprecated, one should use ‘cohortIds’ instead.

Job Openings

• Alex Asiimwe shared three openings at Gilead that could be of interest to OHDSI collaborators. There are openings for a Director, RWE – Data Science, a Director, Data Acquisition, and a Senior Director, Head of Data Office. You can learn more about each position and apply using the links above.

• Linying Zhang shared openings for both a Postdoc and a Senior Data Analyst at the Washington University School of Medicine in St. Louis. Successful candidates will work on causal machine learning and responsible AI for reliable real-world evidence generation. Interested applicants should send a CV and cover letter to linyingz@wustl.edu.

• Nathan Hall introduced a summer internship at Johnson & Johnson for an Epidemiology UX/Web Design Intern. This internship provides a unique opportunity to merge design principles with epidemiological research, contributing to the advancement of real-world evidence applications. In this role, you will have the opportunity to blend your passion for user experience (UX) and web design with the field of epidemiology, contributing to impactful projects that enhance our ability to derive insights from health data. More information and an application link are available here.

The University of North Carolina Chapel Hill CTSA is hiring a Research Informatics Specialist. This is a remote position (US only, with mostly East Coast hours). This person will join a skilled and highly collaborative team of data analysts, software developers, and data scientists within our CTSA. The core purpose of this position is to support the All of Us Center for Linkage and Acquisition of Data project. We are looking for folks with SQL and health care and/or claims data experience, especially OMOP.

There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM.

Slides

Phenotype Phebruary Update | Workgroup OKRs + Community Updates

Videos

Workgroup Updates (Methods Research, HADES, Perinatal and Reproductive Health, Registry, Steering Group)

Phenotype Phebruary Update #1

The third installment of Phenotype Phebruary is approaching, and the leadership team provided an overview of the initiative, its importance in research, and how this version of Phenotype Phebruary will take place in the OHDSI community. This talk also included a “Phenotype 101” session, as well as a community vote on four phenotypes to be focused on during the month. The selections were Alzheimer’s, pulmonary hypertension, major depression disorder and prostate cancer. This session was led by:

• Azza Shoaibi – Director, Observational Health Data Analytics, Janssen Research and Development 
• Jamie Weaver – Associate Director, Observational Health Data Analytics, Janssen Research and Development
• Anna Ostropolets – Associate Director, Observational Health Data Analytics, Janssen Research and Development

Patrick Ryan and Asieh Golozar also provided comments. You can sign up to take part in Phenotype Phebruary, and you can follow updates via the OHDSI forums.

Community Updates

• Congratulations to the team of Soobeen Seol, Jimyung Park, Chungsoo Kim, Dong Yun Lee, and Rae Woong Park on the publication of RHEA: Real-World Observational Health Data Exploration Application in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Sujin Gan, Chungsoo Kim, Dong Yun Lee, and Rae Woong Park on the publication of Prediction Models for Readmission Using Home Healthcare Notes and OMOP-CDM in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Scott L. DuVall, Craig G. Parker, Amanda R. Shields, Patrick R. Alba, Julie A. Lynch, Michael E. Matheny, and Aaron W.C. Kamauu on the publication of Toward Real-World Reproducibility: Verifying Value Sets for Clinical Research in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Piper Ranallo, Bronwyn Southwell, Christopher Tignanelli, Steven G. Johnson, Richard Krueger, Tess Sevareid-Groth, Adam Carvel, and Genevieve B. Melton on the publication of Promoting Learning Health System Cycles by Optimizing EHR Data Clinical Concept Encoding Processes in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of ChulHyoung Park, Sang Jun Park, Da Yun Lee, Seng Chan You, Kihwang Lee, and Rae Woong Park on the publication of Multi-Institutional Collaborative Research Using Ophthalmic Medical Image Data Standardized by Radiology Common Data Model (R-CDM) in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Seol Whan Oh, Soo Jeong Ko, Yun Seon Im, Surin Jung, Bo Yeon Choi, Jae Yoon Kim, Sunghyeon Park, Wona Choi, and In Young Choi on the publication of Development of Integrated Data Quality Management System for Observational Medical Outcomes Partnership Common Data Model in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Martijn Schuemie, Jenna Reps, Adam Black, Frank Defalco, Lee Evans, Egill Fridgeirsson, James P. Gilbert, Chris Knoll, Martin Lavallee, Gowtham A. Rao, Peter Rijnbeek, Katy Sadowski, Anthony Sena, Joel Swerdel, Ross D. Williams, and Marc Suchard on the publication of Health-Analytics Data to Evidence Suite (HADES): Open-Source Software for Observational Research in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Jiyun Cha, Eun Kyoung Ahn, Young-Heum Yoon, and Man Young Park on the publication of Feasibility of Applying the OMOP Common Data Model to Traditional Eastern Asian Medicine Dataset in Volume 310 of Studies in Health Technology and Informatics.

• Congratulations to the team of Najia Ahmadi, Quang Vu Nguyen, Martin Sedlmayr, and Markus Wolfien on the publication of A comparative patient-level prediction study in OMOP CDM: applicative potential and insights from synthetic data in Scientific Reports.

• February community calls will focus on both Phenotype Phebruary updates and 2024 OKR announcements by our various workgroups. All workgroup leads/representatives should sign up for one of the upcoming community calls using this link.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Transforming the Optum® Enriched Oncology module to OMOP CDM (Dmitry Dymshyts)
Tuesday — Community Contribution to the OHDSI Vocabularies: moving towards collaborative shared resource (Oleg Zhuk)
Wednesday — Evaluating confounding adjustment when sample size is small (Martijn Schuemie)
Thursday — Using a Continuous Quality Improvement (CQI) Approach for Gap Analysis of OHDSI/ATLAS as An Enterprise Self-Service Analytics Platform by Academic Medical Centers (Selvin Soby)
Friday — Risk of aortic aneurysm or dissection following exposure to fluoroquinolone antibiotics (Jack Jenetzki)

HADES Development Updates

• Martijn Schuemie announced the release of SelfControlledCaseSeries 5.1.1. This contains a fix of a minor bug introduced in 5.1.0.

Job Openings

• Linying Zhang shared openings for both a Postdoc and a Senior Data Analyst at the Washington University School of Medicine in St. Louis. Successful candidates will work on causal machine learning and responsible AI for reliable real-world evidence generation. Interested applicants should send a CV and cover letter to linyingz@wustl.edu.

The University of North Carolina Chapel Hill CTSA is hiring a Research Informatics Specialist. This is a remote position (US only, with mostly East Coast hours). This person will join a skilled and highly collaborative team of data analysts, software developers, and data scientists within our CTSA. The core purpose of this position is to support the All of Us Center for Linkage and Acquisition of Data project. We are looking for folks with SQL and health care and/or claims data experience, especially OMOP.

• There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM.

Slides

Introduction to Phenotype Phebruary | Community Updates

Video Presentation

The Jan. 23 community call looked at the recent UK Study-A-Thon, held last November at Saint Hilda’s College. The event focused on the use of fluoroquinolones across geographies and over time, as well as on the epidemiology and characterization of rectal prolapse and rectopexy. At the end of an intense week, the team generated three draft manuscripts almost ready for submission, and at least four conference abstracts were in the making.

Community Updates

• Congratulations to the team of Xu Zuo, Yujia Zhou, Jon Duke, George Hripcsak, Nigam Shah, Juan Banda, Ruth Reeves, Timothy Miller, Lemuel Waitman, Karthik Natarajan, and Hua Xu on the publication of Standardizing Multi-site Clinical Note Titles to LOINC Document Ontology: A Transformer-based Approach in the AMIA Annual Symposium Proceedings.

• Congratulations to the team of Huzaifa Khan, Abu Saleh Mohammad Mosa, Vyshnavi Paka, Md Kamruz Zaman Rana, Vasanthi Mandhadi, Soliman Islam, Hua Xu, James C McClay, Sraboni Sarker, Praveen Rao, and Lemuel Waitman on the publication of Mapping Clinical Documents to the Logical Observation Identifiers, Names and Codes (LOINC) Document Ontology using Electronic Health Record Systems Structured Metadata in the AMIA Annual Symposium Proceedings.

• Congratulations to the team of Joel Swerdel and Mitchell Conover on the publication of Comparing broad and narrow phenotype algorithms: differences in performance characteristics and immortal time incurred in the Journal of Pharmacy & Pharmaceutical Sciences.

• Registration is open for the 2024 Oxford Summer School: Real world evidence using the OMOP Common Data Model, which will be held June 17-21, 2024 at the University of Oxford. The Real World Evidence Summer School will provide participants with the tools and concepts necessary to plan and execute Real World Evidence studies, with a focus on the use of the OMOP common data model. Learn more about the program here.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Mapping of Critical Care EHR Flowsheet data to the OMOP CDM via SSSOM (Polina Talapova)
Tuesday — Paving the way to estimate daily dose in OMOP CDM for Drug Utilisation Studies in DARWIN EU® (Theresa Burkard)
Wednesday — Generating Synthetic Electronic Health Records in OMOP using GPT (Chao Peng)
Thursday — Comparing concepts extracted from clinical Dutch text to conditions in the structured data (Tom Seinen)
Friday — Finding a constrained number of predictor phenotypes for multiple outcome prediction (Jenna Repa) 

Job Openings

The University of North Carolina Chapel Hill CTSA is hiring a Research Informatics Specialist. This is a remote position (US only, with mostly East Coast hours). This person will join a skilled and highly collaborative team of data analysts, software developers, and data scientists within our CTSA. The core purpose of this position is to support the All of Us Center for Linkage and Acquisition of Data project. We are looking for folks with SQL and health care and/or claims data experience, especially OMOP.

• There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM.

Slides

MHRA and the use of RWE | Use of systemic fluoroquinolones in primary care and hospital settings in the UK: a drug utilisation study | Rectopexy & the search for devices | Community Updates

Video Presentation

0:00 – Daniel Prieto-Alhambra – Professor of Pharmaco- and Device Epidemiology, University of Oxford (Introduction)
1:28 – Katherine Donegan – Head of Epidemiology, MHRA (MHRA and the use of RWE)
13:40 – Annika Jodicke – Senior Researcher in Pharmacoepidemiology, University of Oxford (Use of systemic fluoroquinolones in primary care and hospital settings in the UK: a drug utilisation study)
28:52 – Jennifer Lane – NIHR Clinical Lecturer in Trauma and Orthopaedic Surgery, Barts Bone and Joint Health, Queen Mary University of London (Rectopexy & the search for devices)

The Jan. 16 community call featured multiple unrecorded breakout session meant to stimulate future collaboration opportunities throughout the community. The video below highlights the updates shared at the beginning of the call, including a brief presentation on a recent community publication, Real-World Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents.

Community Updates

• Congratulations to the team of Qiong Wu, Jiayi Tong, Bingyu Zhang, Dazheng Zhang, Jiajie Chen, Yuqing Lei, Yiwen Lu, Yudong Wang, Lu Li, Yishan Shen, Jie Xu, L. Charles Bailey, Jiang Bian, Dimitri A. Christakis, Megan L. Fitzgerald, Kathryn Hirabayashi, Ravi Jhaveri, Alka Khaitan, Tianchen Lyu, Suchitra Rao, Hanieh Razzaghi, Hayden T. Schwenk, Fei Wang, Margot I. Gage Witvliet, Eric J. Tchetgen Tchetgen, Jeffrey S. Morris, Christopher B. Forrest, and Yong Chen on the publication of Real-World Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents in Annals of Internal Medicine.

• Congratulations to the team of Martí Català, Núria Mercadé-Besora, Raivo Kolde, Nhung T H Trinh, Elena Roel, Edward Burn, Trishna Rathod-Mistry, Kristin Kostka, Wai Yi Man, Antonella Delmestri, Prof Hedvig M E Nordeng, Anneli Uusküla, Talita Duarte-Salles, Daniel Prieto-Alhambra, and Annika M Jödicke on the publication of The effectiveness of COVID-19 vaccines to prevent long COVID symptoms: staggered cohort study of data from the UK, Spain, and Estonia in The Lancet Respiratory Medicine.

Anna Ostropolets will lead the next edition of the CBER Best Seminar Seminar series, which will be held Wednesday, Jan. 17, at 11 am ET. Anna will lead a session entitled “KEEPER: Standardized structured data from electronic health records as an alternative to chart review for case adjudication and phenotype evaluation” which will be virtual and available to anybody. More information and the registration link are available here.

• Chungsoo Kim is a PhD candidate in the Department of Biomedical Informatics at Ajou University College of Medicine. Since joining OHDSI in 2019, he has participated in and led several research projects at OHDSI. He currently participates in OHDSI working groups, including PatientLevelPrediction and the APAC group. He also served as a tutorial instructor for the 2019 OHDSI Korea International Symposium. Chungsoo discusses his research focuses, his involvement in the OHDSI community, the growth of OHDSI around the Asia-Pacific region, and plenty more in the latest Collaborator Spotlight.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Development of psychiatric common data model (P-CDM) leveraging psychiatric scales (Dong Yun Lee)

Tuesday — Integrating large language models and real-world evidence into an automated drug indication taxonomy development workflow (Yilu Fang)

Wednesday — Making OHDSI Tooling accessible to Researchers and Students in a HIPAA Compliant Platform (Hannah Morgan-Cooper)

Thursday — Trend in Prescription Pattern in Heart Failure Medications (Septi Melisa)

Friday — PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide Multi-Institutional Multimorbidity Analysis (Siwei Zhang)

Job Openings

• There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM. 

Slides

Community Updates

Video Presentation

Happy New Year! Patrick Ryan led the first community call of the year for a discussion on what OHDSI can achieve together in 2024. You can watch the recording or check out the slides below. 

Community Updates

• Congratulations to the team of Yoon Jin Choi, Tae Jun Kim, Chang Seok Bang, Yong Kang Lee, Moon Won Lee, Su Youn Nam, Woon Geon Shin, and Seung In Seo on the publication of Changing trends and characteristics of peptic ulcer disease: A multicenter study from 2010 to 2019 in Korea in the World Journal of Gastroenterology.

• Congratulations to the team of Pierre Heudel, Hugo Crochet, Thierry Durand, Philippe Zrounba, and JeanYves Blay on the publication of From data strategy to implementation to advance cancer research and cancer care: A French comprehensive cancer center experience in PLOS Digital Health.

• Congratulations to the team of Cynthia Yang, Egill Fridgeirsson, Jan Kors, Jenna Reps and Peter Rijnbeek on the publication of Impact of random oversampling and random undersampling on the performance of prediction models developed using observational health data in the Journal of Big Data.

• Congratulations to the team of Christian Reich, Anna Ostropolets, Patrick Ryan, Peter Rijnbeek, Martijn Schuemie, Alexander Davydov, Dmitry Dymshyts, and George Hripcsak on the publication of OHDSI Standardized Vocabularies-a large-scale centralized reference ontology for international data harmonization in JAMIA.

• Congratulations to the team of Qiong Wu, Jiayi Tong, Bingyu Zhang, Dazheng Zhang, Jiajie Chen, Yuqing Lei, Yiwen Lu, Yudong Wang, Lu Li, Yishan Shen, Jie Xu, L. Charles Bailey, Jiang Bian, Dimitri A. Christakis, Megan L. Fitzgerald, Kathryn Hirabayashi, Ravi Jhaveri, Alka Khaitan, Tianchen Lyu, Suchitra Rao, Hanieh Razzaghi, Hayden T. Schwenk, Fei Wang, Margot I. Gage Witvliet, Eric J. Tchetgen Tchetgen, Jeffrey S. Morris, Christopher B. Forrest, and Yong Chen on the publication of Real-World Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents in Annals of Internal Medicine.

• Chungsoo Kim is a PhD candidate in the Department of Biomedical Informatics at Ajou University College of Medicine. Since joining OHDSI in 2019, he has participated in and led several research projects at OHDSI. He currently participates in OHDSI working groups, including PatientLevelPrediction and the APAC group. He also served as a tutorial instructor for the 2019 OHDSI Korea International Symposium. Chungsoo discusses his research focuses, his involvement in the OHDSI community, the growth of OHDSI around the Asia-Pacific region, and plenty more in the latest Collaborator Spotlight.

• The latest edition of the OHDSI newsletter is now available, and it includes the December video presentations of the year in review and OHDSI’s first 10 years. It also features community updates, December publications and presentations, and plenty more.

• Research from the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — A Toxin Vocabulary for the OMOP CDM Park (Maksym Trofymenko)
Tuesday — Developing a perinatal expansion table for the OMOP common data model (Alicia Abellan)
Wednesday — External validation using clinical domain knowledge from the SNOMED medical terms hierarchy (Henrik John)
Thursday — Estimating the comparative risk of kidney failure associated with intravitreal anti-vascular endothelial growth factor (anti-VEGF) exposure in patients with blinding diseases (Cindy Cai)
Friday — Characteristics and outcomes of over a million inflammatory bowel disease subjects in seven countries: a multinational cohort study (Chen Yanover)

HADES Development Updates

• Martiijn Schuemie announced the releases of CohortMethod 5.2.0 and EmpiricalCalibration 3.1.2. The CohortMethod release focuses on generalizability, by comparing the population after all adjustments (e.g. PS matching) to the population before all adjustments, and report any characteristics that have changed. The choice of population to consider for generalizability is now driven by your analysis choices. For example, if you use PS matching, (implying ATT), generalizability will be computed for the target (treated) population.

• Egill Fridgeirsson announced the release of DeepPatientLevelPrediction 2.0.3. This bugfix release only includes one change which was necessary because one of my dependencies introduced a breaking change (polars) which broke some functionality in the package.

• Joel Swerdel announced the release of PheValuator 2.2.11. This adds the capability to include multiple visits per subject in the evaluation cohort.

Job Openings

• There is an opening for a Data Steward position at the EBMT. Among the responsibilities is the design, implementation and testing of new data collection processes including data collection forms (DCFs) development, as well as the mapping of new items from DCFs to the OMOP CDM.

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